SCHEDULE 14A

                                 (Rule 14a-101)

                    INFORMATION REQUIRED IN PROXY STATEMENTS

                            SCHEDULE 14A INFORMATION

           PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES
                      EXCHANGE ACT OF 1934 (AMENDMENT NO. )

  Filed  by  the  Registrant  [ X ]
  Filed  by a  Party  other  than  the Registrant [   ]

  Check the appropriate box:

     [   ]  Preliminary Proxy Statement

     [   ]  Confidential, For Use of the Commission Only (as Permitted
            by Rule 14a-6(e)(2))

     [ X ]  Definitive Proxy Statement

     [   ]  Definitive Additional Materials

     [   ]  Soliciting Material Under Rule 14a-12


                              UNITED-GUARDIAN, INC.
             -----------------------------------------------------
                (Name of Registrant as specified in Its Charter)

 -----------------------------------------------------------------------
 (Name of Person(s) Filing Proxy Statement, if Other Than the Registrant)

Payment of Filing Fee (Check the appropriate box):

     [X]  No fee required.

     [ ]  Fee computed on table below per Exchange Act Rules 14a-6(i)(1) and
          0-11.

            (1)  Title of each class of securities to which transaction
                 applies:

            ---------------------------------------------------------------

            (2)  Aggregate number of securities to which transaction applies:

            ---------------------------------------------------------------

            (3)   Per  unit  price  or other  underlying  value  of  transaction
                  computed  pursuant  to  Exchange  Act Rule 0-11 (set forth the



                                        1

                  amount on which the filing fee is calculated  and state how it
                  was determined):

            ---------------------------------------------------------------

            (4)   Proposed maximum aggregate value of transaction:

            ---------------------------------------------------------------

            (5)   Total fee paid:

            ---------------------------------------------------------------

     [ ] Fee paid previously with preliminary materials.

     [ ] Check box if any  part of the fee is  offset as  provided  by  Exchange
         Act Rule  0-11(a)(2)  and identify the filing for which the  offsetting
         fee was paid  previously.  Identify the previous filing by registration
         statement number, or the form or schedule and the date of its filing.

            (1)  Amount Previously Paid:

            ---------------------------------------------------------------

            (2)  Form, Schedule or Registration Statement No.:

            ---------------------------------------------------------------

            (3)  Filing Party:

            ---------------------------------------------------------------

            (4)  Date Filed:

            ---------------------------------------------------------------






















                                        2

                              UNITED-GUARDIAN, INC.
           230 Marcus Boulevard - P.O. Box 18050 - Hauppauge, NY 11788

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS

                             -----------------------
                             To Be Held May 17, 2006
                             -----------------------


To the Stockholders of UNITED-GUARDIAN, INC.:

     You are hereby  notified  that the annual  meeting of the  stockholders  of
UNITED-GUARDIAN,  INC., a Delaware corporation (the "Company"),  will be held at
the Sheraton Long Island Hotel,  110  Vanderbilt  Motor Parkway,  Smithtown,  NY
11788 on  Wednesday,  May 17, 2006 at 10:00 A.M.  local time,  for the following
purposes:

     1.   To elect  nine (9)  directors  to serve  until the next  annual
          meeting  of  the   stockholders   and  until  their  respective
          successors are elected and qualified;

     2.   To ratify the selection by the Company of Eisner LLP as its
          independent certified public accountants for the fiscal year
          ending December 31, 2006; and

     3.   To transact  such other matters as may properly come before the
          meeting or any adjournment thereof.

     Only  stockholders of record at the close of business on March 31, 2006 are
entitled to notice of and to vote at the meeting.

                                        By order of the Board of Directors
                                        Robert S. Rubinger, Secretary

Dated: April 19, 2006



                                RETURN OF PROXIES

          A Proxy and  Business  Reply  Envelope are enclosed for your
          use if you do  not plan to  attend  the  Annual  Meeting  in
          person.  We urge each  stockholder  who is  unable to attend
          the Annual Meeting to vote promptly by signing and returning
          his or her proxy,  regardless of  the number of shares held.








                                        3

                              UNITED-GUARDIAN, INC.
           230 Marcus Boulevard - P.O. Box 18050 - Hauppauge, NY 11788
                                 (631) 273-0900

                                 Proxy Statement
                                 ---------------

     The   enclosed   proxy  is   solicited   by  the  Board  of   Directors  of
UNITED-GUARDIAN,  INC.  (the  "Company")  for  use  at  the  Annual  Meeting  of
Stockholders  (the "Annual  Meeting") to be held at 10:00 A.M.,  local time,  on
Wednesday, May 17, 2006, at the Sheraton Long Island Hotel, 110 Vanderbilt Motor
Parkway,  Smithtown,  NY 11788, and at any adjournments thereof. A proxy granted
hereunder  is  revocable  at any time before it is voted by (a) a duly  executed
proxy bearing a later date,  (b) written  notice to the Secretary of the Company
received  by the  Company at any time  before  such proxy is voted at the Annual
Meeting, or (c) revocation in person at the Annual Meeting.

     It is  anticipated  that  the  mailing  of  this  Proxy  Statement  and the
accompanying Proxy to Stockholders will commence on or about April 19, 2006.

                             SOLICITATION OF PROXIES

     The  persons  named as proxies  are Dr.  Alfred R.  Globus  and  Kenneth H.
Globus.

     All shares represented by properly executed,  unrevoked proxies received in
proper  form  and in time  for  use at the  Annual  Meeting  will  be  voted  in
accordance  with the  directions  specified  thereon and otherwise in accordance
with the judgment of the persons  designated  as proxies.  Any proxy on which no
direction is  specified  will be voted in the favor of the nominees to the Board
of Directors  listed in this Proxy Statement and in favor of the ratification of
Eisner LLP as the Company's  independent  certified  public  accountants for the
fiscal year ending December 31, 2006.

     The cost of preparing, assembling and mailing the Notice of Annual Meeting,
Proxy Statement,  proxy card and other materials enclosed,  will be borne by the
Company.  In  addition  to the  solicitation  of  proxies  by use of the  mails,
officers and employees of the Company may solicit proxies by telephone, telegram
or personal interview.  They will not receive additional  compensation for their
effort. The Company will request brokerage houses and other custodians, nominees
and  fiduciaries to forward  soliciting  materials to the  beneficial  owners of
stock held of record by such persons,  and will reimburse such persons for their
expenses in  forwarding  soliciting  material.  The Company does not  anticipate
paying any compensation to any other party for the solicitation of proxies.

                  VOTING SECURITIES AND PRINCIPAL STOCKHOLDERS
                  --------------------------------------------

Outstanding Shares And Voting Rights
------------------------------------

     Only holders of record of the Company's  Common  Stock,  par value $.10 per
share  ("Common  Stock"),  at the close of business on March 31,  2006,  will be
entitled  to notice of and to vote at the  Annual  Meeting.  On March 31,  2006,
there were 4,942,139 shares of Common Stock outstanding.  Each outstanding share
of Common  Stock is entitled to one vote on all matters  submitted  to a vote of
the stockholders at the Annual Meeting,  which vote may be given in person or by
proxy. There are no cumulative voting rights.


                                        4

     The nine (9) nominees for director  receiving the greatest  number of votes
cast by the holders of Common Stock will be elected directors.

     The affirmative vote of the holders of a majority of shares of Common Stock
present,  in person or by proxy,  and eligible to vote at the Annual  Meeting is
necessary  for the  approval  of the  proposal  to ratify the  selection  by the
Company of Eisner LLP as the Company's  independent  certified public accountant
for the fiscal year ending December 31, 2006.

     Under Delaware law, shares as to which a stockholder  abstains or withholds
authority  to vote and  shares as to which a broker  indicates  that it does not
have  discretionary  authority to vote ("broker  non-votes")  will be treated as
present at the Annual Meeting for the purposes of determining a quorum.  Proxies
marked  "Withhold  Authority"  with  respect  to the  election  of  one or  more
directors  will not be  counted  in  determining  who are the nine  persons  who
received the  greatest  number of votes in the  election of  directors.  Proxies
marked "Abstain" with respect to the ratification of the selection of Eisner LLP
as the Company's  independent  certified  public  accountant for the fiscal year
ending December 31, 2006, will have the effect of a vote against ratification.

     THE BOARD OF DIRECTORS RECOMMENDS A VOTE "FOR" THE ELECTION OF THE NOMINEES
NAMED.  PROXIES  WILL BE VOTED "FOR" THE  ELECTION OF THE  NOMINEES  NAMED IF NO
DIRECTION IS GIVEN IN THE PROXIES.

Principal Stockholders
----------------------

     The  following  table sets forth the shares of the  Company's  Common Stock
(the only class of stock  issued and  outstanding)  owned  beneficially  by each
person  who,  as of  March  1,  2006,  is known  by the  Company  to have  owned
beneficially more than 5% of the outstanding Common Stock.

Name and Address                             Amount and Nature        Percent
of Beneficial Owner                         of Beneficial Owner       of Class
-------------------                         -------------------      ----------

Dr. Alfred R. Globus   .......................  1,306,484 (1)           26.4%
26-53 210th Street
Bayside, NY 11360

Kenneth H. Globus   ..........................    765,553 (2)           15.5%
19 McCulloch Dr.
Dix Hills, NY 11746

Irwin Uran   .................................    556,339               11.3%
9903 Santa Monica Blvd., #843
Beverly Hills, CA 90212

Banque Carnegie Luxembourg S.A.       |
Carnegie Fund Management Company S.A. |
Centre Europe, 5, Place de la Gare    |
L-1616 Luxembourg City, Luxembourg    |
         &                             ........   269,600 (3)            5.5%
D Carnegie & Co AB                    |
Carnegie Investment Bank AB           |
Vastra Tradgardsgatan 15              |
SE-103 38, Stockholm, Sweden          |


     (1)  Includes  1,267,240  shares  held  directly  and  39,244  shares  held
beneficially  as follows:  14,966 shares owned by the Foundation for Science and
Theology Inc., of which Dr. Globus is President and Director; 23,500 shares held
by his wife; 658 shares controlled as Executor of the estate of Florence Globus;
and 120 shares held as legal guardian for his son.

     (2)  Includes   510,853  shares  held  directly  and  255,300  shares  held
beneficially as follows: 199,900 shares as Trustee; 54,800 shares held by wife.

     (3)  Represents  shares held by Carnegie  Fund  Management  Company S.A., a
wholly owned  subsidiary of Banque Carnegie  Luxembourg  S.A., which is a wholly
owned subsidiary of Carnegie Investment Bank AB, which in turn is a wholly owned
subsidiary of D Carnegie & Co. AB. Carnegie Investment Bank AB is the Investment
Manager for Carnegie Fund Management Company S.A.



                                        5

Security Ownership Of Management
--------------------------------

     The following  information is furnished with respect to ownership of shares
of Common Stock, par value $.10 per share, as of March 1, 2006, by each Director
and by all  Directors  and  Officers  of the  Company  as a group (13  persons).
Ownership  of shares  by the  persons  named  below  includes  sole  voting  and
investment power held by such persons.

               Name                        Number of Shares     Percent of Class
         --------------------              ----------------     ----------------
         Dr. Alfred R. Globus                1,306,484 (1)           26.4%
         Henry P. Globus                           940                 *
         Charles W. Castanza                     6,705                 *
         Robert S. Rubinger                      5,137                 *
         Kenneth H. Globus                     765,553 (2)           15.5%
         Lawrence F. Maietta                     4,000                 *
         Arthur M. Dresner                       9,000                 *
         Andrew A. Boccone                           0                 *
         Christopher W. Nolan, Sr.                   0                 *
         Joseph J. Vernice                      11,526                 *
         All other officers (3 persons)          2,920 (3)             *

         All officers and directors
         as a group (13 persons)             2,112,265 (1)(2)(3)     42.7%


      *  Less than one percent (1%)

     (1) Includes   1,267,240  shares  held  directly  and  39,244  shares  held
         beneficially  as follows:  14,966  shares owned by the  Foundation  for
         Science  and  Theology  Inc.,  of which  Dr.  Globus is  President  and
         Director;  23,500  shares held by his wife;  658 shares  controlled  as
         Executor of the estate of Florence Globus; and 120 shares held as legal
         guardian for his son.

     (2) Includes   510,853   shares  held  directly  and  255,300  shares  held
         beneficially as follows:  199,900 shares as Trustee; 54,800 shares held
         by wife.

     (3) Includes currently  exercisable  options to purchase 2600 shares by two
         officers who are not Directors.


                        DIRECTORS AND EXECUTIVE OFFICERS
                        --------------------------------

Nominees For Election As Directors
----------------------------------

     Nine  directors are to be elected to serve until the next Annual Meeting of
Stockholders  and until their  successors  have been elected and qualified.  Set
forth in the table below are the names of all nominees  designated by management
for election as  directors,  the  principal  occupation  or  employment  of each
nominee for the past five years, his present  positions with the Company and the
year he was first elected a director.





                                        6

                                                                      Year First
Name and Position                  Principal Occupation During         Elected a
with the Company             Age       the Past Five Years             Director
---------------              ---   -------------------------           ---------

Dr. Alfred R. Globus         85     From July 1988 to date,                 1942
C.E.O. and Director                 Chairman of the Board
                                    and C.E.O. of the Company.
                                    For more than 5  years prior
                                    thereto, Chairman of the Board
                                    and President. From February 1982
                                    to November 1997 Chief Financial
                                    Officer of the Company.

Henry P. Globus              83     From July 1988 to date,                 1947
Director                            business consultant. For more
                                    than  five  years  prior
                                    thereto, Executive Vice President
                                    of the Company.

Charles W. Castanza          73     From March 2000 to date, Senior         1982
Senior Vice President               Vice President of the Company.
                                    From   April  1986  to  March
                                    2000, Vice President of the Company.
                                    For more than five years prior thereto,
                                    Operations  Manager of Chemicals &
                                    Pharmaceuticals for the Company.

Robert S. Rubinger           63     From July 1988 to date, Executive       1982
Executive Vice President,           Vice President and Secretary. For
Secretary, and Director             more than five years prior thereto,
                                    Vice President and Secretary of the
                                    Company. Treasurer of the Company
                                    from May, 1994 to May, 2004.

Kenneth H. Globus            54     From July 1988 to date, President       1984
President, Chief                    and General Counsel of the Company.
Financial Officer                   For more  than 5 years  prior
and Director                        thereto,  Vice  President and
                                    General    Counsel   of   the
                                    Company. Chief Financial Officer
                                    since November 1997.

Lawrence F. Maietta          48     Partner in the accounting firm of       1994
Director                            Bonamassa, Maietta & Cartelli, LLP,
                                    Brooklyn,  NY, since October 1991.
                                    For more than 5 years prior  thereto,
                                    partner in the accounting  firm  of
                                    Wilfred  Wyler  &  Co. Controller of
                                    the Company from October 1991 to
                                    November 1997.

Arthur M. Dresner            64     Partner in the law firm of Reed         1997
Director                            Smith LLP, New York, NY since
                                    January  2003 and engaged as "Of


                                        7

                                    Counsel" to that firm from June 1998
                                    to January 2003. Attorney in private
                                    practice and independent business
                                    consultant since January 1997. For
                                    more  than 5  years  prior  thereto,
                                    a Vice President in  corporate
                                    development and general management of
                                    International Specialty Products Inc.,
                                    Wayne, N.J.

Andrew A. Boccone            60     Independent business consultant.        2002
Director                            From 1990 until his retirement
                                    in  2001, President of Kline &
                                    Company, Little Falls, NJ, an
                                    international  business consulting
                                    and market research firm.

Christopher W. Nolan, Sr     41     Managing Director (since March, 2006)   2005
Director                            and Executive Director (2002 to 2006)
                                    in Mergers & Acquisitions ("M&A") for
                                    Rabobank International, New York, NY.
                                    From 2000 to 2002, V. P. in M&A for
                                    Deutsche Bank Securities, Inc., New York,
                                    NY. In 2000, V.P. with Salomon Smith
                                    Barney, New York, NY. From 1992-2000,
                                    V.P., Corporate Development and Investor
                                    Relations for ISP Inc., Wayne, NJ.


     Dr. Alfred R. Globus and Henry P. Globus are brothers. Kenneth H. Globus is
the son of Henry P. Globus and the nephew of Dr. Alfred R. Globus.  There are no
other family relationships between any Director or Officer of the Company.


Executive Officers and Significant Employees
--------------------------------------------

Dr. Alfred R. Globus       85       From July 1988 to date, Chairman of the
C. E. O. and Director               Board and C.E.O. of the Company. For more
                                    than 5 years prior thereto, Chairman of the
                                    Board and President. From February 1982 to
                                    November 1997, Chief Financial Officer of
                                    the Company.

Kenneth H. Globus          54       From July 1988 to date, President and
President, Chief                    General Counsel of the Company. For more
Financial Officer                   than 5 years prior thereto, Vice President
and Director                        and General Counsel of the Company. Chief
                                    Financial Officer since November 1997.




                                        8

Robert S. Rubinger         63       From July 1988 to date, Executive Vice
Executive Vice                      President and Secretary of the Company. For
President, Secretary                more than 5 years prior thereto, Vice
and Director                        President and Secretary. Treasurer of the
                                    Company from May 1994 to May 2004.

Charles W. Castanza        73       From March 2000 to date, Senior Vice
Senior Vice President               President of the Company. From April 1986 to
                                    March 2000, Vice President of the Company.
                                    For more than 5 years prior thereto,
                                    Operations Manager of Chemicals &
                                    Pharmaceuticals of the Company.

Derek Hampson              66       From October 1987 to date, Vice President of
Vice President                      the Company. Since 1971 Manager of the
                                    Company's Eastern Chemical Corp. subsidiary.

Joseph J. Vernice          47       From February 1995 to date, Vice President
Vice President                      of the Company. From November 1991 until
                                    February 1995, Assistant Vice President of
                                    the Company. Since 1988 Manager of Research
                                    & Development and since 1991 Director of
                                    Technical Services of the Company.

Peter A. Hiltunen          47       From July 2002 to date, Vice President of
Vice President                      the Company. From November 1991 until July
                                    2002, Assistant Vice President of the
                                    Company. Since 1982 Production Manager for
                                    the Company.

Cecile M. Brophy           57       From May 2004 to date, Treasurer of the
Treasurer and                       Company. From November, 1997 to date,
Controller                          Controller of the Company.  From May 1994
                                    to November 1997, Accounting Manager for
                                    the Company.


Section 16(a) Beneficial Ownership Reporting Compliance
------------------------------------------------------

     Section 16(a) of the Securities  Exchange Act of 1934 (the "Act")  requires
the Company's  officers,  directors and persons who own more than 10% of a class
of the Company's  equity  securities to file reports of ownership and changes in
ownership  with  the  Securities  and  Exchange  Commission  ("SEC").  Officers,
directors and greater than 10%  stockholders  are required by SEC regulations to
furnish the Company with copies of all Section  16(a) forms they file.  Based on
(i) a review of copies of Forms 3, 4, and 5 and any amendments thereto furnished
to the Company  during and with  respect to the fiscal year ended  December  31,
2005 and (ii) statements signed by each responsible  person regarding his or her
obligation  to file Forms 3, 4, and 5 during the fiscal year ended  December 31,
2005,  the  Company   believes  that  all  persons   subject  to  the  reporting
requirements  pursuant to Section  16(a) filed the required  reports on a timely
basis during and with respect to the fiscal year ended December 31, 2005.




                                        9

Meetings And Compensation
-------------------------

     During the fiscal year ended December 31, 2005, the Board of Directors held
four meetings. All Directors attended all four meetings.

     The Board of Directors  has an Audit  Committee,  established in accordance
with Section 3(a)(58)(A) of the Securities Exchange Act of 1934,  to oversee the
accounting  and  financial  reporting  processes  of the Company and to meet and
review  with  the  Company's independent auditors the plan, scope and results of
its audits.  Members of the Audit Committee are Mssrs. Arthur M. Dresner, Andrew
A. Boccone, and Christopher W. Nolan, Sr. All of the Audit Committee members are
independent as that term is defined in Section 121(A)  of the listing  standards
of the American Stock Exchange. Under newly adopted rules of the American  Stock
Exchange  ("AMEX"),  the Board of Directors is required to make certain findings
about the independence and  qualifications of the members of the Audit Committee
of the Board.  In addition to assessing  the  independence  of the members under
AMEX rules, the Board also considered the requirements of Section  10A(m)(3) and
Rule 10A-3 under the Securities Exchange Act of 1934. As a result of its review,
the  Board  determined  that  all of the  members  of the  Audit  Committee  are
independent. The Board of Directors has determined that the Audit Committee does
not have a member who is a financial expert.  The  reason  for  the absence of a
financial  expert  is  that the  Audit  Committee  did not have one when the new
requirement  became  effective,  and the  Board of Directors determined that the
small size of the Company does not justify recruiting one. Instead,  Lawrence F.
Maietta, a Certified Public Accountant and former member of the Audit Committee,
now acts as an advisor to the Audit Committee. Mr. Maietta is not independent as
that term is defined by the listing standards of the  American  Stock  Exchange.
There were four meetings in the fiscal year ended  December 31, 2005.  Committee
members  and  Mr. Maietta  receive  a  fee of $1,000.00 for the Annual Committee
Meeting and $500 for each quarterly  meeting. The Committee Chairman, Mr. Arthur
M. Dresner,  receives  an additional $500.00 for each meeting and the member who
records  the  minutes  of  each  meeting receives an additional $100.00 for each
meeting.

     The  Board  of  Directors  has  a  Stock  Option   Committee   which  meets
periodically  to grant  options  under the 2004 Stock Option  Plan,  and in past
years under the now expired 1993  Employee  Incentive  Stock Option Plan and the
Non-Statutory  Stock Option Plan for  Directors.  The committee  consists of two
directors.  No fee is paid to such committee members. There were no Stock Option
Committee meetings during the fiscal year ended December 31, 2005.

     The Board of Directors  has a  Compensation  Committee  which was formed in
1999 for the purpose of recommending to the Board the compensation for corporate
officers for the ensuing year. Members of the Compensation Committee are Messrs.
Lawrence F. Maietta, Arthur M. Dresner, and Andrew A. Boccone. Kenneth H. Globus
acts as advisor to the Committee representing management. The Committee held one
meeting in 2005. Committee members receive a fee of $1,000.00 for attending each
meeting.

     The Board does not have a Nominating Committee. The full Board of Directors
fulfills  the role of a nominating  committee.  Final  selections  are made by a
majority of the independent  directors.  It is the position of the Board that it
is  appropriate  for the  Company  not to have a separate  nominating  committee
because the size,  composition and collective  independence of the Board enables
it to  adequately  fulfill the functions of a standing  committee.  The American
Stock  Exchange  does not  require  the  Company to have a  separate  nominating



                                       10

committee  but  does  require  that  board  nominees  be  selected  by  either a
nominating committee comprised solely of independent  directors or by a majority
of the independent directors. Within the meaning of the listing standards of the
American  Stock Exchange  three  directors are now  considered independent. They
are Messrs. Arthur M. Dresner, Andrew A. Boccone, and Christopher W. Nolan, Sr.

     The  Board  identifies   director   candidates  through  a  combination  of
referrals,  including by management,  existing  board members and  stockholders.
Once a  candidate  has been  identified,  the  board  reviews  the  individual's
experience and background,  and may discuss the proposed nominee with the source
of  the  recommendation.   If  the  independent   directors  believe  it  to  be
appropriate,  such directors may meet with the proposed  nominee before making a
final  determination  whether to  include  the  proposed  nominee as a member of
management's  slate of  director  nominees  submitted  to the  stockholders  for
election to the board.The Board will evaluate  stockholder-nominated  candidates
under the same criteria as director-nominated  candidates.  Stockholders wishing
to refer  director  candidates  to the Board  should do so in  writing  and they
should be delivered to the Board c/o Corporate Secretary, United-Guardian, Inc.,
230 Marcus Blvd.,  P.O. Box 18050,  Hauppauge,  NY 11788. The Board of Directors
has adopted a corporate  resolution  with  regard to the  nominating  process as
discussed above.

     In  2005  all of the Directors attended the Annual Meeting of stockholders.
Historically, all of the Directors have attended the Annual Meeting.

Compensation of Directors
-------------------------

     Non-officer directors receive a fee of $1,500.00 for each meeting attended.
All other directors receive $1,000.00 for each meeting.

Audit Committee Report
----------------------

     The  Audit  Committee  of the  Board of  Directors  is  comprised  of three
directors:  Arthur M. Dresner,  Andrew A. Boccone, and Christopher W. Nolan, Sr.
All of the Audit  Committee  members are  independent as that term is defined in
Section 121(A) of the listing standards of the American Stock Exchange.

     The Audit  Committee  assists  the Board of  Directors  in  fulfilling  its
oversight  responsibilities  by reviewing the Company's  consolidated  financial
reports,  its internal  financial  and  accounting  controls,  and its auditing,
accounting and financial reporting processes generally.  In June 2000, the Board
of Directors approved and adopted a written Audit Committee Charter.

     In discharging its oversight  responsibilities regarding the audit process,
the Audit Committee  reviewed and discussed the audited  consolidated  financial
statements of the Company as of and for the year ended  December 31, 2005,  with
Company  management and Eisner LLP  ("Eisner"),  the independent  auditors.  The
Audit  Committee  received  the written  disclosures  and the letter from Eisner
required  by  Independence   Standards   Board  Standard  No.  1,   Independence
Discussions with Audit Committees, (as may be amended or supplemented) discussed
with Eisner any relationships which might impair that firm's independence from


                                        11

management   and  the  Company  and   satisfied   itself  as  to  the  auditors'
independence.  The Audit  Committee  reviewed  and  discussed  with  Eisner  all
communications  required by generally  accepted  auditing  standards,  including
Statement on Auditing Standards No. 61, Communications with Audit Committees, as
amended.

     Based upon these reviews and discussions,  the Audit Committee  recommended
to the Board of Directors  that the  Company's  audited  consolidated  financial
statements  for the year ended  December 31, 2005,  be included in the Company's
Annual  Report on Form  10-KSB for the fiscal year ended  December  31, 2005 for
filing with the Securities and Exchange Commission.

   /s/ Arthur M. Dresner    /s/ Andrew A. Boccone   /s/Christopher W. Nolan, Sr.

     The foregoing Audit  Committee  Report shall not be deemed "filed" with the
Securities and Exchange  Commission or subject to the  liabilities of Section 18
of the Securities Exchange Act of 1934.

Principal Accountant Fees and Services
--------------------------------------

Audit Fees

     The  aggregate  fees  billed by Eisner  LLP for the audit of the  Company's
annual  financial  statements  for  FY-2005  and the  reviews  of the  financial
statements  included  in the  Company's  quarterly  reports  on Form  10-QSB for
FY-2005  were  approximately  $65,600  including  out of  pocket  expenses.  The
aggregate  fees  billed by  Eisner  LLP for the  audit of the  Company's  annual
financial  statements  for  FY-2004 and the review of the  financial  statements
included in the Company's  quarterly  reports on Form 10-QSB during FY-2004 were
approximately $55,500.

Audit-Related Fees

     During FY-2005 Eisner LLP billed the Company $2,972 for fees related to its
review of the Company's  compliance with section 404 of the  Sarbanes-Oxley  Act
("SOX").  During  FY-2004  there  were no fees  billed by  Eisner  LLP that were
related to SOX compliance.  No other fees were billed by Eisner LLP for the last
two fiscal years that were reasonably related to the performance of the audit or
review of the Company's financial statements and not reported under "Audit Fees"
above.

Tax Fees

     There  were no other  fees  billed by Eisner LLP during the last two fiscal
years that related to tax compliance, tax advice, or tax planning.

All Other Fees

     There  were no other  fees  billed by Eisner LLP during the last two fiscal
years for other products and services provided by Eisner LLP.

Pre-approval Policies for Audit Services
----------------------------------------

     The Audit Committee of the Company's Board of Directors meets  periodically
to review and approve the scope of the services to be provided to the Company by
its  independent  accountant,  as well to review and discuss any issues that may
arise during an engagement.  The Audit  Committee is  responsible  for the prior
approval of every engagement of the Company's independent auditors to perform



                                        12

audit and  permissible  non-audit  services  for the Company  (such as quarterly
reviews,  tax matters,  consultation on new accounting and disclosure  standards
and, in future years, reporting on management's internal controls assessment.)

     Before  the  auditors  are  engaged to provide  those  services,  the chief
financial  officer and the controller  will make a  recommendation  to the Audit
Committee regarding each of the services to be performed,  including the fees to
be  charged  for such  services.  At the  request  of the  Audit  Committee  the
independent  auditors and/or management shall  periodically  report to the Audit
Committee  regarding the extent of services  being  provided by the  independent
auditors, and the fees for the services performed to date.


                COMPENSATION OF DIRECTORS AND EXECUTIVE OFFICERS

Summary Compensation Table
--------------------------

     The following  table sets forth for the three years ended December 31, 2005
certain  information  concerning the  compensation  paid or accrued to the Chief
Executive Officer of the Company and the other executive officers of the Company
whose  total  salary  and bonus for the  fiscal  year ended  December  31,  2005
exceeded $100,000.


                             Annual Compensation                  Long-Term Compensation
                      ---------------------------------    ---------------------------------
                                                                 Awards           Payments
                                                           --------------------- -----------

       (a)            (b)       (c)         (d)     (e)      (f)          (g)        (h)       (i)
                                                   Other               Securities              All
Name and                                          Annual   Restricted  Underlying             Other
Principal                                         Compen-    Stock      Options     LTIP      Compen-
Position              Year*   Salary       Bonus  sation    Award(s)    /SARs       Payouts   sation
                                ($)         ($)    ($)       ($)         (#)         ($)       ($)
                                                                       
Alfred R. Globus,     2003    $152,845     3,500   -- 1      --          --          --        --
Chief Executive       2004    $130,005     6,000   -- 1      --          --          --        --
Officer               2005    $135,022     6,500   -- 1      --          --          --        --

Kenneth H. Globus,    2003    $197,550    28,000   -- 1      --          --          --        $4,303 2
President             2004    $202,810    45,000   -- 1      --          --          --        $4,871 2
                      2005    $209,936    50,000   -- 1      --          --          --        $5,380 2

Robert S. Rubinger,   2003    $127,136     7,500   -- 1      --          --          --        $2,641 2
Executive Vice        2004    $131,134    11,400   -- 1      --          --          --        $2,794 2
President             2005    $138,310    12,000   -- 1      --          --          --        $4,414 2

Charles W. Castanza   2003    $108,434     6,500   -- 1      --          --          --        $2,254 2
Senior Vice President 2004    $111,819     9,750   -- 1      --          --          --        $2,381 2
                      2005    $118,398    10,500   -- 1      --          --          --        $3,783 2

Joseph J. Vernice     2003    $103,736     9,000   -- 1      --          --          --        $2,212 2
Vice President        2004    $105,265    13,500   -- 1      --          --          --        $2,330 2
                      2005    $109,343    15,000   -- 1      --          --          --        $3,662 2


* Year ended on December 31 of such year.

                                        13

     1    The amount of personal benefits received by Alfred R. Globus,  Kenneth
          H.  Globus,  Robert S.  Rubinger,  Charles W.  Castanza  and Joseph J.
          Vernice for these periods did not exceed reporting thresholds.

     2    In the fiscal year ended December 31, 2005,  under its 401(k) Plan for
          all of its employees,  the  Company made a contribution of up to 3% of
          each employee's pay for an employee's elective  deferral of 6% of pay.
          In the fiscal years ended December 31, 2004 and 2003, the Company made
          a  contribution  of  up to 2% of each employee's pay for an employee's
          elective deferral of 4% of pay.  These amounts represent the Company's
          contribution for each year.

Stock Options
-------------

     During the fiscal  year ended  December  31, 2005 the Company did not grant
options to purchase  Common  Stock under the 2004 Stock Option Plan or under the
now expired 1993 Employee  Incentive  Stock Option Plan or  Non-Statutory  Stock
Option Plan for Directors.

     The following table sets forth certain information with respect to exercise
of stock options  during the fiscal year ended December 31, 2005, by the persons
in the Summary Compensation Table above and the value as of December 31, 2005 of
unexercised options.


                                                           Number of Securities        Value of Unexercised
                                                          Underlying Unexercised     in-the-Money Options/SARs
                         Shares Acquired     Value       Options/SARs at FY-End (#)          at FY-End ($)
Name                     on exercise (#)  Realized ($)   Exercisable/Unexercisable   Exercisable/Unexercisable
----                     ---------------  ------------   -------------------------   -------------------------
                                                                                
Alfred R. Globus               -               -                 0/0                        0/0

Kenneth H. Globus            1,000           4,040               0/0                        0/0

Robert S. Rubinger             -               -                 0/0                        0/0

Charles W. Castanza            -               -                 0/0                        0/0

Joseph J. Vernice              -               -                 0/0                        0/0



     The  Company  has  not  adopted  a  Long  Term Incentive Plan for Officers,
Directors or employees.

                             APPOINTMENT OF AUDITORS
                             -----------------------

     The firm of Eisner LLP,  independent  certified public accountants,  of New
York,  N.Y., has been selected by the Audit  Committee of the Board of Directors
to be the  independent  auditors  of the  Company  for the  fiscal  year  ending
December 31, 2006. The selection of such firm is subject to  ratification by the
stockholders  at the Annual Meeting.  Management  believes that the firm is well
qualified and recommends a vote in favor of the ratification.

     Representatives  of Eisner  LLP are  expected  to be  present at the Annual
Meeting and will have an opportunity  to make a statement,  if they desire to do
so, and will be available to respond to appropriate questions.

     THE BOARD OF  DIRECTORS  RECOMMENDS  A VOTE "FOR" THE  RATIFICATION  OF THE
APPOINTMENT OF EISNER LLP TO SERVE AS OUR INDEPENDENT ACCOUNTANTS FOR THE FISCAL
YEAR ENDING DECEMBER 31, 2006.  PROXIES WILL BE VOTED "FOR" THE  RATIFICATION OF
THE APPOINTMENT OF EISNER LLP IF NO DIRECTION IS GIVEN IN THE PROXIES.

                                       14

                          ANNUAL REPORT TO STOCKHOLDERS
                          -----------------------------

     The Annual Report to  Stockholders  for the fiscal year ended  December 31,
2005 accompanies this Proxy Statement.

                              STOCKHOLDER PROPOSALS
                              ---------------------

     Proposals of  stockholders  for possible  consideration  at the 2007 Annual
Meeting  (expected to be held in May 2007) must be received by the  Secretary of
the Company not later than January 15, 2007 to be  considered  for  inclusion in
the proxy  statement for that meeting if  appropriate  for  consideration  under
applicable securities laws. Stockholders who wish to make a proposal at the 2007
Annual  Meeting-other  than one that will be  included  in the  Company's  proxy
materials-must notify the Company no earlier than November 15, 2006 and no later
than March 6, 2007. If a stockholder  who wishes to present a proposal  fails to
notify the Company by March 6, 2007,  the  stockholder  would not be entitled to
present the proposal at the meeting. If, however,  notwithstanding the foregoing
procedure, the proposal is brought before the meeting, then under the Securities
and Exchange  Commission's  proxy rules the proxies solicited by management with
respect to the 2007 Annual Meeting will confer  discretionary  voting  authority
with respect to the stockholder's proposal on the persons selected by management
to vote proxies. If a stockholder makes a timely  notification,  the proxies may
still exercise  discretionary  voting authority under  circumstances  consistent
with the Securities and Exchange Commission's proxy rules.

Stockholder Communications with the Board
-----------------------------------------

     The Board of Directors has adopted the following procedure for stockholders
to  send   communications   to  the  Board.   Stockholders   who  wish  to  send
communications   to  directors  should  refer  to  the  Company's   website  at:
www.u-g.com and direct those  communications to Mr. Arthur M. Dresner,  Chairman
of the Audit Committee, whose email address is posted there.

                                 OTHER BUSINESS
                                 --------------

     Management of the Company knows of no business  other than that referred to
in the  foregoing  Notice of Annual  Meeting and Proxy  Statement  that may come
before the Annual Meeting.

                                       By order of the Board of Directors
                                       Robert S. Rubinger, Secretary
Dated:  April 19, 2006

                          UNITED-GUARDIAN, INC.

        THE COMPANY  WILL  FURNISH,  WITHOUT  CHARGE,  A COPY OF ITS
        ANNUAL  REPORT ON FORM  10-KSB  FOR THE  FISCAL  YEAR  ENDED
        DECEMBER  31,  2005,   INCLUDING  FINANCIAL  STATEMENTS  AND
        FINANCIAL STATEMENT  SCHEDULES,  BUT EXCLUDING EXHIBITS,  TO
        EACH   STOCKHOLDER   WHO  REQUESTS  THE  10-KSB  IN  WRITING
        ADDRESSED  TO  ROBERT  S.  RUBINGER,   CORPORATE  SECRETARY,
        UNITED-GUARDIAN,  INC., P.O. BOX 18050, HAUPPAUGE,  NEW YORK
        11788.
                                        15

-------------------------------------------------------------------------------
                          UNITED-GUARDIAN, INC.
         230 Marcus Blvd. - P. 0. Box 18050 - Hauppauge, NY 11788

        THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF DIRECTORS

     The undersigned hereby appoints Dr. Alfred R. Globus and Kenneth H. Globus,
and each of them, as proxies, each with the power to appoint his substitute, and
hereby  authorizes  them to represent  and to vote, as designated on the reverse
side, all the shares of common stock of United-Guardian,  Inc. held of record by
the  undersigned on March 31, 2006 at the annual meeting of  stockholders  to be
held on  Wednesday,  May 17, 2006,  10:00 a.m.  local time at the Sheraton  Long
Island Hotel,  110  Vanderbilt  Motor Parkway,  Smithtown,  N.Y.  11788,  or any
adjournment thereof.

        Please mark, sign, date and return the proxy card promptly, using
                              the enclosed envelope

       (Continued, and to be marked, dated and signed, on the other side)
--------------------------------------------------------------------------------
                                     PROXY

THIS PROXY,  WHEN PROPERLY  EXECUTED,  WILL BE VOTED IN THE MANNER DIRECTED
HEREIN BY THE UNDERSIGNED STOCKHOLDER.  IF NO DIRECTION IS MADE, THIS PROXY
WILL BE VOTED FOR PROPOSALS 1 AND 2.

1.    ELECTION OF DIRECTORS.
                                      _                                       _
       FOR all nominees listed below |_|      WITHHOLD AUTHORITY to vote for |_|
        (except as marked to the               all nominees listed below
         contrary below)

           (INSTRUCTION: TO WITHHOLD AUTHORITY TO VOTE FOR ANY INDIVIDUAL
             NOMINEE, STRIKE A LINE THROUGH THE NOMINEE'S NAME BELOW.)

     Dr. Alfred R. Globus   Charles W. Castanza    Arthur M. Dresner
     Henry P. Globus        Robert S. Rubinger     Lawrence F. Maietta
     Kenneth H. Globus      Andrew A. Boccone      Christopher W. Nolan, Sr.

2.    PROPOSAL  TO APPROVE  THE  APPOINTMENT  OF EISNER  LLP AS THE  INDEPENDENT
      PUBLIC  ACCOUNTANTS OF THE COMPANY FOR THE FISCAL YEAR ENDING DECEMBER 31,
      2006.
                         _                  _                 _
                    FOR |_|        AGAINST |_|       ABSTAIN |_|

      In their  discretion,  the proxies  are  authorized  to vote upon  matters
      incident to the conduct of the meeting and upon such other business (which
      the Board of Directors  did not know,  prior to making this  solicitation,
      would come before the meeting) as may properly  come before the meeting or
      any adjournment thereof.
                                                     Company ID:
                                                     Proxy Number:
                                                     Account Number:

Signature:____________________  Signature:______________________ Dated:_________

     Please sign exactly as name appears  hereon.  When shares are held by joint
tenants,  both should sign. When signing as attorney,  executor,  administrator,
trustee or guardian,  please give full title.  If a corporation,  please sign in
full corporate name by president or other authorized  officer.  If a partnership
please sign in partnership name by authorized person.