SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported) May 13, 2003 Progenics Pharmaceuticals, Inc. (Exact name of registrant as specified in its charter) Delaware 000-23143 13-3379479 (State or other jurisdiction (Commission (IRS Employer of incorporation) File Number) Identification No.) 777 Old Saw Mill River Road, Tarrytown, New York 10591 (Address of principal executive offices) (Zip Code) Registrant's telephone number, including area code (914) 789-2800 (Former name or former address, if changed since last report.) Item 7. Financial Statements and Exhibits (c) Exhibits Exhibit 99.1 Description Press Release dated May 13, 2003 (filed herewith). Item 9. Regulation FD Disclosure. On May 13, 2003, Progenics Pharmaceuticals, Inc. issued a press release announcing the initiation of a phase 2 clinical trial of its investigational drug methylnaltrexone for the treatment of post-operative ileus, a paralysis of the gastrointestinal tract that often occurs after surgery. The press release also published new phase 1 clinical trial data that shows that methylnaltrexone stimulates gastrointestinal mobility in absence of opioids. A copy of the press release is attached as Exhibit 99.1. The information furnished pursuant to Item 9 in this Form 8-K shall not be deemed to be "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934 or otherwise subject to the liabilities of that Section, unless we specifically incorporate it by reference in a document filed under the Securities Act of 1933 or the Securities Exchange Act of 1934. We undertake no duty or obligation to publicly update or revise the information furnished pursuant to Item 9 in this Form 8-K. SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. PROGENICS PHARMACEUTICALS, INC. By: /s/ PHILIP K. YACHMETZ ----------------------- Philip K. Yachmetz Vice President, General Counsel and Secretary Date: May 13, 2003