FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * SULLIVAN PATRICK J   2. Issuer Name and Ticker or Trading Symbol HOLOGIC INC [HOLX] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Executive Chairman (Last) (First) (Middle) 35 CROSBY DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 11/14/2007 (Street) BEDFORD, MA 01730 4. If Amendment, Date Original Filed(Month/Day/Year) 11/16/2007 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock (1) 11/14/2007   M   23,339 A $ 31.62 152,403 D   Common Stock (2) 11/14/2007   M   36,661 A $ 31.82 189,064 D   Common Stock (3) 11/14/2007   S   60,000 D $ 63.1245 129,064 D   Common Stock (2) 11/15/2007   M   60,000 A $ 31.82 189,064 D   Common Stock (3) 11/15/2007   S   60,000 D $ 64.2275 129,064 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Nonqualified Stock Option (2)

$ 31.82

11/15/2007

M

60,000

10/22/2007

01/10/2012

Common Stock

60,000

(4)

284,664

D

Nonqualified Stock Option (1)

$ 31.62

11/14/2007

M

23,339

10/22/2007

02/09/2011

Common Stock

23,339

(4)

73,727

D

Nonqualified Stock Option (2)

$ 31.82

11/14/2007

M

36,661

10/22/2007

01/10/2012

Common Stock

36,661

(4)

344,644

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
SULLIVAN PATRICK J 35 CROSBY DRIVE BEDFORD, MA 01730	X		Executive Chairman

Signatures

/S/ Mark J. Casey, Attorney-in-Fact For: Patrick J. Sullivan		01/15/2008
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Originally issued under Cytyc Corporation's 2004 Omnibus Stock Plan in transactions exempt from Section 16 under Rule 16b-3.
(2)	Originally issued under Cytyc Corporation's 1995 Stock Plan in transactions exempt from Section 16 under 16b-3.
(3)	The sale reported on this Form 4 was made pursuant to a written trading plan adopted in accordance with SEC Rule 10b-5 on September 14, 2007.
(4)	Price not applicable to this transaction.

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