To Prospectus dated August 9, 2006, as supplemented by the Prospectus Supplement
No. 1 dated September 8, 2006 and the Prospectus Supplement No. 6 dated January 18, 2007

Filed Pursuant to Rule 424(b)(7)
Registration File No. 333-136450

Charles River Laboratories International, Inc.
2.25% Convertible Senior Notes due 2013 and Common Stock Issuable Upon
Conversion of the Notes

Interest payable June 15 and December 15

This prospectus supplement supplements information contained in that certain prospectus supplement No. 6 dated January 18, 2007 to the prospectus supplement No. 1 dated September 8, 2006 to the prospectus dated August 9, 2006 of Charles River Laboratories International, Inc., which we collectively refer to as the “prospectus,” covering resale by selling securityholders of our 2.25% Convertible Senior Notes due 2013 and common stock issuable upon conversion of the notes. This prospectus supplement is not complete without, and may not be delivered or utilized except in connection with, the prospectus, including any amendments or supplements thereto. The terms of the notes are set forth in the prospectus.

See "Risk Factors" beginning on page S-5 of the prospectus supplement No. 1 dated September 8, 2006 for a discussion of certain risks that you should consider in connection with an investment in the notes or in shares of our common stock.

Neither the Securities and Exchange Commission, any state securities commission nor any other United States regulatory authority has approved or disapproved of these securities or determined if this prospectus supplement or the prospectus is truthful or complete. Any representation to the contrary is a criminal offense.






The date of this prospectus supplement is June 6, 2007

The table appearing under the section entitled “Selling Securityholders” on page S-2 of the prospectus supplement No. 6 dated January 18, 2007 is amended by adding the following information below, which is based on information received from the selling securityholders on or prior to June 5, 2007.

    Aggregate Principal            
    Amount of Notes   Percentage of   Number of Shares   Percentage of
    That Are Owned and   Notes   of Common Stock   Common Stock
Name   May Be Sold   Outstanding   that May Be Sold(1)   Outstanding(2)

LibertyView Convertible Arbitrage Fund, LP (3)(4)   $ 600,000   *   12,260                      *
LibertyView Funds, LP (3)(4)   $ 2,000,000   *   40,867                      *
LibertyView Socially Responsible Fund, LP (3)(4)   $ 250,000   *   5,108                      *
Benchmark Select Managers Fund (4)   $ 250,000   *   5,108                      *
Trust D for a Portion of the Assets of Kodak Retirement                
Income Plan (4)   $ 1,900,000   *   38,824                      *


* Less than one percent (1%)

(1) Assumes conversion of all of the holder’s notes at a conversion rate of 20.4337 shares of common stock per $1,000 principal amount of notes. This conversion rate is subject to adjustment, however, as described under “Description of Notes—Conversion rights.” As a result, the number of shares of common stock issuable upon conversion of the notes may increase or decrease in the future.

(2) Calculated based on Rule 13d-3(d)(1)(i) of the Exchange Act, using 67,303,504 shares of common stock outstanding as of May 1, 2007. In calculating this amount for each holder, we treated as outstanding the number of shares of common stock issuable upon conversion of all of that holder’s notes, but we did not assume conversion of any other holder’s notes.

(3) This selling securityholder is an affiliate of a broker-dealer.

(4) LibertyView Convertible, LibertyView Funds, LibertyView Socially Responsible, Benchmark and Trust D have a common investment advisor, Neuberger Berman, LLC, that has voting and dispositive power over the shares held by them, which is exercised by Richard A. Meckler. Since the entities have hired a common investment advisor, these entities are likely to vote together and there may be common investors within the different accounts managed by the same investment advisor. The General Partner of LibertyView Convertible, LibertyView Funds and LibertyView Socially Responsible is Neuberger Berman Asset Management, LLC, which is affiliated with Neuberger Berman, LLC, a registered broker-dealer. The shares were purchased for investment in the ordinary course of business and at the time of purchase, there were no agreements or understandings, directly or indirectly, with any person to distribute the shares. Benchmark and Trust D are not in any way affiliated with a broker-dealer.

Information about other selling securityholders will be set forth in additional prospectus supplements, if required.