UPDATE 4-Shire, Takeda reach breakthrough in $64 bln deal talks
April 24, 2018 at 19:57 PM EDT
LONDON/NEW YORK, April 24 (Reuters) - London-listed drugmaker Shire Plc said on Tuesday it was willing to recommend to its shareholders a deal with Takeda Pharmaceutical Co, after the Japanese company sweetened its acquisition offer to 46 billion pounds ($64 billion).