New York, USA – September 30, 2022 – Creative Bioarray, one of the world’s leading biotechnology products and services providers, has been working hand-in-hand with scientists to provide the most cutting-edge and innovative research tools for life science research. Creative Bioarray remains a leading supplier of innovative, high-quality life science reagents to customers around the world, including pharmaceutical companies, universities, and research institutions, to advance life science research and enable new discoveries. Recently, Creative Bioarray announced the release of a broad range of iPSC reprogramming kits to accelerate stem cell research.
Creative Bioarray provides the fastest integration-free method for iPSC reprogramming, designed to meet customers’ project- and assay-specific requirements for cell identity and function. iPSCs are scalable from one million to one billion cells and can be delivered on a predictable schedule. The derivation of iPSCs has sparked widespread enthusiasm for the development of new models of human disease, enhanced drug discovery platforms, and wider use of autologous cell therapy. The advent of reprogramming technologies has enabled disease-specific iPSCs to be used in established directed differentiation protocols. Improvements in reprogramming methods have increased the efficiency of iPSC derivation and the quality of iPSC lines in use. Uncorrected cells differentiated from patient-derived iPSCs have been used for drug screening. Currently, a small number of drug candidates identified in iPSC-based systems are being studied in human trials.
For the creation of iPSCs, the expression of reprogramming factors as mRNAs is a zero-footprint technique available. A single RNA strand comprising OCT-4, KLF-4, SOX-2 and GLIS1 enables extremely efficient reprogramming via a single transfection step without the need for any viral intermediates or host genome integration.
Creative Bioarray’s advanced generative technology can be used to transform skin, blood and urine samples. The resulting iPSCs have low transgene persistence, increased chromosomal stability, and reduced clonal variation. It also reduces the risk of tumorigenesis and abnormal karyotype due to reduced copy number variation due to RNA reprogramming. Creative Bioarray is committed to providing customers with best-in-class iPSC reprogramming services that will greatly contribute to the success of iPSC programs.
Creative Bioarray offers a wide range of kits and related reagents, including QualiStem® Episomal iPSC Reprogramming kit, QualiStem® RNA iPSC Reprogramming kit, QualiStem® Retrovirus iPSC Reprogramming kit and QualiStem® Lentivirus iPSC Reprogramming kit etc.
“We ensure efficient iPSC cell derivation from different cells through advanced technologies, including delivery of reprogramming factors via mRNA.” said Hannah Cole, the marketing director of Creative Bioarray, she also added, “We offer our clients tailored iPSC reprogramming services, as well as optional differentiation strategies (ready-to-use cell resources and flexible, efficient and iterative custom solutions to meet specific application and program needs).”
About Creative Bioarray
Creative Bioarray is dedicated to offering customers innovative biotechnology products and services for research use to greatly enhance and drive innovation and standards in science. As a well-recognized industry leader with more than 10 years of experience and in-house expert support, Creative Bioarray has already countenanced research all around the world.