UNITED STATES

                       SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                  SCHEDULE 14A
                Proxy Statement pursuant to Section 14(a) of the
                         Securities Exchange Act of 1934

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      14a-6(e)(2))
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|_|   Soliciting Material Under Rule 14a-12

                             SIGA TECHNOLOGIES, INC.
                (Name of Registrant as Specified in Its Charter)

                                       N/A
    (Name of Person(s) Filing Proxy Statement, if other than the Registrant)

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                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170
                                 (212) 672-9100

April 27, 2007

Dear Stockholder:

      You are cordially invited to attend our 2007 Annual Meeting of
Stockholders on May 30, 2007, at 10:00 a.m. (local time), at the offices of
Kramer Levin Naftalis & Frankel LLP, 1177 Avenue of the Americas, 29th Floor,
New York, New York 10036. On the following pages you will find the formal notice
of annual meeting and proxy statement.

      To ensure that you are represented at the Annual Meeting, whether or not
you plan to attend the meeting in person, please read carefully the accompanying
proxy statement, which describes the matters to be voted upon, and please
complete, date, sign and return the enclosed proxy card promptly.

      I hope that you will attend the meeting and I look forward to seeing you
there.

                                    Sincerely,

                                    /s/ Eric A. Rose
                                    ----------------
                                    Eric A. Rose, M.D.
                                    Chief Executive Officer
                                    and Chairman of the Board



                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170

                    NOTICE OF ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON MAY 30, 2007

      NOTICE IS HEREBY GIVEN that the Annual Meeting of Stockholders (the
"Annual Meeting") of SIGA Technologies, Inc., a Delaware corporation ("SIGA"),
will be held on Wednesday, May 30, 2007, at 10:00 a.m. (local time), at the
offices of Kramer Levin Naftalis & Frankel LLP, 1177 Avenue of the Americas,
29th Floor, New York, New York 10036, and at any adjournment.

      At the Annual Meeting, SIGA's stockholders will be voting on proposals to
do the following:

      1.    To elect ten directors to the Board of Directors of SIGA;

      2.    To ratify the appointment of PricewaterhouseCoopers LLP as the
            independent registered public accounting firm of SIGA for the fiscal
            year ending December 31, 2007; and

      3.    To transact such other business as may properly come before the
            Annual Meeting or at any adjournment or postponement thereof.

      Stockholders of record at the close of business on April 25, 2007 are
entitled to notice of, and to vote at, the Annual Meeting or any adjournment or
postponement thereof. A list of such stockholders will be available at the
Annual Meeting and for any purpose related to the Annual Meeting, during the ten
days prior to the Annual Meeting, at SIGA's office, during ordinary business
hours.

      All stockholders are cordially invited to attend the Annual Meeting. If
you do not expect to be present at the Annual Meeting, you are requested to fill
in, date and sign the enclosed proxy and mail it promptly in the enclosed
envelope to make sure that your shares are represented at the Annual Meeting. In
the event you decide to attend the Annual Meeting in person, you may, if you
desire, revoke your proxy and vote your shares in person.

                             YOUR VOTE IS IMPORTANT

   IF YOU ARE UNABLE TO BE PRESENT PERSONALLY, PLEASE MARK, SIGN AND DATE THE
 ENCLOSED PROXY, WHICH IS BEING SOLICITED BY THE BOARD OF DIRECTORS, AND RETURN
                     IT PROMPTLY IN THE ENCLOSED ENVELOPE.

                             By Order of the Board of Directors,


                             /s/ Thomas N. Konatich
                             ----------------------
                             Thomas N. Konatich
                             Secretary
New York, New York
April 27, 2007



                             SIGA Technologies, Inc.
                         420 Lexington Avenue, Suite 408
                            New York, New York 10170

                                 --------------
                                 PROXY STATEMENT
                         ANNUAL MEETING OF STOCKHOLDERS
                                  MAY 30, 2007

                                 --------------

      This proxy statement is furnished to  stockholders  of SIGA  Technologies,
Inc.   ("SIGA")  in  connection  with  the  solicitation  of  proxies,   in  the
accompanying  form, by the Board of Directors of SIGA (the "Board of Directors")
for use in voting at the Annual Meeting of Stockholders  (the "Annual  Meeting")
to be held at the offices of Kramer Levin Naftalis & Frankel LLP, 1177 Avenue of
the Americas, 29th Floor, New York, New York 10036, on Wednesday,  May 30, 2007,
at 10:00 a.m., and at any adjournment or postponement thereof.

      This proxy statement and the  accompanying  form of proxy, are first being
mailed to stockholders on or about April 27, 2007.

                   VOTING RIGHTS AND SOLICITATION OF PROXIES

Purpose of the Annual Meeting

      The  specific  proposals  to be  considered  and acted  upon at the Annual
Meeting  are  summarized  in  the  accompanying  Notice  of  Annual  Meeting  of
Stockholders. Each proposal is described in more detail in this proxy statement.

Record Date and Outstanding Shares

      The Board of  Directors  has fixed the close of business on April 25, 2007
as the record date (the "Record  Date") for the  determination  of  stockholders
entitled to notice of, and to vote at, the Annual Meeting.  Only stockholders of
record at the close of  business  on the Record Date will be entitled to vote at
the Annual Meeting or any and all adjournments or postponements  thereof.  As of
the Record Date,  SIGA had issued and  outstanding  33,014,410  shares of common
stock, par value $.0001 per share ("Common Stock").

Voting at the Annual Meeting

      Each share of Common Stock outstanding on the Record Date will be entitled
to one vote on each matter submitted to a vote of the  stockholders.  Cumulative
voting by stockholders is not permitted.

      The presence,  in person or by proxy,  of the holders of a majority of the
votes  entitled  to be cast by the  stockholders  entitled to vote at the Annual
Meeting is necessary to constitute a quorum.  Abstentions and broker "non-votes"
are  counted as present  and  entitled to vote for  purposes  of  determining  a
quorum.  A  broker  "non-vote"  occurs  when  a  nominee  holding  shares  for a
beneficial owner does not vote on a particular proposal because the nominee does
not  have  discretionary  voting  power  for  that  particular  item and has not
received instructions from the beneficial owner.

      For the election of directors,  a plurality of the votes cast is required.
Abstentions  and broker  "non-votes"  are not  considered for the purpose of the
election of directors.

      For the ratification of the appointment of  PricewaterhouseCoopers  LLP as
the independent  registered  public  accounting firm of SIGA for the fiscal year
ending December 31, 2007, the affirmative  vote of a majority of the total votes


                                       1


cast on such  proposal in person or by proxy at the Annual  Meeting is required.
Abstentions and broker  "non-votes" for such proposal are not considered to have
been voted on the proposal.

Revocability and Voting of Proxies

      Any person signing a proxy in the form  accompanying  this proxy statement
has the power to revoke it prior to the Annual  Meeting or at the Annual Meeting
prior to the vote  pursuant  to the proxy.  A proxy may be revoked by any of the
following methods:

o  by  writing a letter  delivered  to Thomas N.  Konatich,  Secretary  of SIGA,
   stating that the proxy is revoked;

o  by submitting another proxy with a later date; or

o  by attending the Annual Meeting and voting in person.

      Please note, however, that if a stockholder's shares are held of record by
a  broker,  bank or other  nominee  and that  stockholder  wishes to vote at the
Annual Meeting,  the stockholder  must bring to the Annual Meeting a letter from
the broker,  bank or other  nominee  confirming  that  stockholder's  beneficial
ownership of the shares.

      Unless we receive specific instructions to the contrary or unless such
proxy is revoked, shares represented by each properly executed proxy will be
voted: (i) FOR the election of each of SIGA's nominees as a director; (ii) FOR
the ratification of the appointment of PricewaterhouseCoopers LLP as the
independent registered public accounting firm of SIGA for the fiscal year ending
December 31, 2007; and (iii) with respect to any other matters that may properly
come before the Annual Meeting, at the discretion of the proxy holders. SIGA
does not presently anticipate that any other business will be presented for
action at the Annual Meeting.

Solicitation

      SIGA  will  pay the  costs  of  soliciting  proxies.  SIGA  may  reimburse
brokerage firms and other persons  representing  beneficial owners of shares for
their  expenses  in  forwarding  solicitation  material  to  beneficial  owners.
Directors, officers and regular employees may also solicit proxies by telephone,
facsimile  or other means or in person.  They will not  receive  any  additional
payments for the solicitation.


                                       2


                                 PROPOSAL NO. 1

                             ELECTION OF DIRECTORS

      Ten directors are to be elected at the Annual Meeting to hold office until
the next Annual Meeting of  Stockholders  and until their  successors  have been
duly elected and qualified.  Unless otherwise instructed, the proxy holders will
vote the proxies  received by them FOR the election of the ten persons  named in
the table  below as  directors  of SIGA.  Proxies  cannot be voted for a greater
number of persons  than the nominees  named.  In the event that any of the below
listed  nominees for director  should  become  unavailable  for election for any
presently  unforeseen  reason,  the persons named in the accompanying proxy form
have the right to use their discretion to vote for a substitute.

      THE BOARD OF DIRECTORS  RECOMMENDS  THAT THE  STOCKHOLDERS  VOTE "FOR" THE
ELECTION  (ITEM 1 OF THE  ENCLOSED  PROXY  CARD) OF DR.  ROSE,  MR.  ANTAL,  MR.
CONSTANCE,  MR. FASMAN,  DR. HAMMER,  DR. MJALLI, DR. OZ, MR. SAVAS, MS. SLOTKIN
AND DR. WEINER AS DIRECTORS.

Director Nominee Information

      The following table sets forth  biographical  information of each director
nominee,  including their ages, data on their business backgrounds and the names
of public  companies  and other  selected  entities for which they also serve as
directors:




         Name                                   Age      Position
         ----                                   ---      --------
                                                   
         Eric A. Rose, M.D.                     54       Chief Executive Officer and Chairman of the Board
         James J. Antal*                        55       Director
         Thomas E. Constance*                   69       Director
         Steven L. Fasman*                      44       Director
         Scott M. Hammer, M.D. *                59       Director
         Adnan M. Mjalli, Ph.D.                 42       Director
         Mehmet C. Oz, M.D. *                   44       Director
         Paul G. Savas*                         44       Director
         Judy S. Slotkin*                       54       Director
         Michael A.  Weiner, M.D. *             60       Director


*     Determined  by the Board of Directors to be  independent  pursuant to Rule
      4200 of the NASD Marketplace Rules.

      Eric A. Rose,  M.D.  was elected  Chairman of the Board of SIGA at a Board
meeting on January 25,  2007.  On March 1, 2007,  Dr. Rose became the  Company's
Chief  Executive  Officer  after taking a leave from his position as Chairman of
the  Department  of Surgery and  Surgeon-in-Chief  of the Columbia  Presbyterian
Center of New York  Presbyterian  Hospital,  a position he has held since August
1994.  Dr. Rose has served as a director of SIGA since April 19, 2001 and served
as Interim  Chief  Executive  Officer of SIGA from April 19, 2001 until June 22,
2001.  Dr. Rose is a past President of the  International  Society for Heart and
Lung Transplantation.  Dr. Rose was recently appointed as Morris & Rose Milstein
Professor  of  Surgery  at  Columbia  University's  College  of  Physicians  and
Surgeons'  Department  of Surgery.  Dr.  Rose is a director  of  Nephros,  Inc.,
PharmaCore, Inc., TransTech Pharma, Inc. and Keryx Biopharmaceuticals,  Inc. Dr.
Rose also holds a position  of  Executive  Vice  President  - Life  Sciences  at
MacAndrews & Forbes Holdings Inc., a SIGA shareholder,  and is a former director
of Nexell  Therapeutics  Inc.  (f/k/a  VimRx).  Dr.  Rose is a graduate  of both
Columbia College and Columbia University College of Physicians & Surgeons.

      James J. Antal has served as a director of SIGA since  November  2004. Mr.
Antal has been an active  consultant and founding  investor in several  Southern
California based emerging  companies since his retirement from Experian in 2002.
He has served as Chief  Financial  Advisor  to Black  Mountain  Gold  Coffee Co.
(2003-2005),  and as Chief  Financial  Officer of Pathway  Data,  Inc.  (2005 to
present).  Mr. Antal joined the Board of Directors and serves as the Chairman of
the audit committee for Cleveland Bio Labs, effective upon the completion of the
Cleveland Bio Labs IPO,  which  occurred in July,  2006. Mr. Antal was the Chief
Financial Officer and Chief Investment Officer from 1996 to 2002 for Experian, a
$1.6 billion global information  services  subsidiary of UK-based GUS plc. Prior
to the GUS acquisition of Experian (the former TRW Inc.  Information Systems and
Services  businesses),  Mr. Antal held various  finance  positions with TRW from
1978 to 1996,  including  Senior VP of Finance for TRW  Information  Systems and
Services and TRW Inc. Corporate Director of


                                       3


Financial  Reporting  and  Accounting.  He earned  his  undergraduate  degree in
accounting from The Ohio State University in 1973, and became a certified public
accountant  (Ohio) in 1974. He engaged in active  practice as a CPA with Ernst &
Ernst until 1978.  Mr.  Antal has served as a director  of First  American  Real
Estate Solutions, an Experian joint venture with First American Financial Corp.

      Thomas E. Constance has served as a director of SIGA since April 19, 2001.
Mr.  Constance is Chairman and, since 1994, a partner of Kramer Levin Naftalis &
Frankel  LLP, a law firm in New York City,  which SIGA has  retained  to provide
legal services.  Mr.  Constance  serves as a Trustee of the M.D. Sass Foundation
and St. Vincent's Services. He also serves on the Advisory Board of Directors of
Barington Capital, L.P.

      Steven L. Fasman has been Senior Vice President-Law at MacAndrews & Forbes
Holdings  Inc.  since 2004.  Prior to that, he served as Vice  President-Law  at
MacAndrews & Forbes from  1998-2003  and Senior  Counsel at  MacAndrews & Forbes
from 1992-1997.  From 1987 to 1992, he was associated with Paul, Weiss, Rifkind,
Wharton & Garrison.  Mr. Fasman was  recommended to the Nominating and Corporate
Governance  Committee for inclusion as a director-nominee by the Chief Executive
Officer.

      Dr.  Hammer is the  Harold C. Neu  Professor  of  Medicine,  Professor  of
Epidemiology  and Chief of the Division of  Infectious  Diseases at the Columbia
University  Medical  Center  (CUMC),  a  position  he has held since  1999.  Dr.
Hammer's  major  investigative  interest is the treatment and  prevention of HIV
disease.  He is an investigator in the National  Institutes of Health  sponsored
AIDS Clinical  Trials Group (ACTG),  a multicenter  organization  which performs
clinical  trials  designed to improve the  understanding  and  treatment  of HIV
infection and its complications. As an ACTG investigator, Dr. Hammer chaired the
two largest national trials of antiretroviral  therapy carried out by that group
in the 1990's,  studies which contributed to the current standard of care of HIV
infection.  In  addition  to his  interest  in the  treatment  of  persons  with
established  HIV  infection,  Dr.  Hammer  is an  investigator  in the  National
Institutes of Health  sponsored HIV Vaccine Trials Network (HVTN), a multicenter
organization whose mission is to develop an effective preventive HIV vaccine. He
is Chair of the AIDS Vaccine  Research  Working Group, an advisory  committee to
the  Division of AIDS,  NIAID.  He is a former Chair of the  Antiviral  Products
Advisory  Committee of the Food and Drug  Administration and currently serves on
the Editorial Board of the New England Journal of Medicine.  Dr. Hammer is Chair
of the International  AIDS Society-USA's  Antiretroviral  Guidelines Panel, is a
member of the Governing Council of the International  AIDS Society,  is a member
of the World Health  Organization's  Strategic and Technical  Advisory Committee
for HIV/AIDS,  serves as Co-Chair of the Steering  Committee of the WHO's Global
HIV  Drug  Resistance  Surveillance  Program,  and  continues  in  his  role  as
Guidelines  Development Group Chair of the WHO's  Antiretroviral  Guidelines for
Resource  Limited  Settings.  He has  served  as a member  of the  International
Advisory  Committees  of  the  Swiss  HIV  Cohort  Study,  the  French  National
Association  for AIDS Research and the HIV-NAT  (Netherlands-Australia-Thailand)
Collaborative  Research  Network.  In his  role  as  Chief  of the  Division  of
Infectious Diseases at CUMC, he is dedicated to fellow and faculty growth and to
the development of state-of-the-art  infection surveillance at the institutional
and regional levels to improve and protect the public health.

      Adnan M.  Mjalli,  Ph.D.  has served as a director  of SIGA since  January
2004. Dr. Mjalli founded TransTech Pharma, Inc., a privately held drug discovery
company  in High  Point,  North  Carolina,  in 1999 and has since  served as its
President,  Chairman of the Board and Chief Executive Officer. He also serves as
Chairman  of the  Board of  PharmaCore,  Inc.  where  he  previously  served  as
President and CEO from December of 1998 to November  2000.  Dr. Mjalli  obtained
his Ph.D. in medicinal  chemistry in 1989 from the University of Exeter, UK. His
postdoctoral  work was  carried out at the  University  of  Rochester.  Prior to
founding   TransTech   Pharma,   he  held  various   positions   of   increasing
responsibility in research and senior management at several  pharmaceutical  and
biotechnology companies, including Merck & Co., Inc.

      Mehmet C. Oz, M.D.  has served as a director of SIGA since April 19, 2001.
Dr. Oz has been a Cardiac Surgeon at Columbia University  Presbyterian  Hospital
since 1993 and a  Professor  of Surgery  and Vice  Chairman  for  Cardiovascular
Services of the  Department of Surgery there since July 2001. Dr. Oz directs the
following  programs  at New  York  University  Presbyterian  Hospital,  Columbia
University:  the Cardiovascular  Institute,  the complementary medicine program,
the clinical  profusion program and clinical trials of new surgical  technology.
Dr. Oz received his undergraduate  degree from Harvard  University in 1982, and,
in  1986,  he  received  a joint  M.D./M.B.A.  degree  from  the  University  of
Pennsylvania Medical School and the Wharton School of Business.

      Paul G. Savas has served as a director  of SIGA since  January  2004.  Mr.
Savas has been an Executive  Vice  President  of Finance at  MacAndrews & Forbes
Holdings,  Inc.  and its  affiliates  since May 2006.  Prior to that,  Mr. Savas


                                       4


served in various positions at MacAndrews & Forbes and its affiliates, including
as Senior Vice  President  of Finance  from  October  2002 until May 2006,  Vice
President  from 1998 until 2002,  and  Director of  Corporate  Finance from 1994
until 1998. Mr. Savas is a director of Rev Holdings LLC,  Clarke American Corp.,
TransTech Pharma, Inc. and PharmaCore, Inc.

      Judy S. Slotkin has served as a director of SIGA since  November 2004. Ms.
Slotkin was Co-Head of the Finance  Committee of the Modern  Africa Fund, a $120
million  private  equity fund,  from 1998 until 2003.  Ms.  Slotkin was formerly
Department  Head  in the  Corporate  Finance  Division  of  Citigroup  (Citibank
Investment Bank) where she was responsible for various  businesses and the first
head of the group's  Capital  Markets  Desk.  Prior to that,  Ms.  Slotkin  held
various positions in the Citigroup (Citibank)  commercial bank. Ms. Slotkin is a
director of Nephros,  Inc.

      Michael A.  Weiner,  M.D. has served as a director of SIGA since April 19,
2001. Dr. Weiner is the Hettinger Professor of Pediatrics at Columbia University
College of Physicians  and Surgeons  since 1996. Dr. Weiner is also the Director
of  Pediatric  Oncology  at New York  Presbyterian  Hospital.  Dr.  Weiner was a
director of Nexell Therapeutics,  Inc. (f/k/a VimRx) from March 1996 to February
1999. Dr. Weiner is a 1972 graduate of the New York State Health Sciences Center
at Syracuse and was a post  graduate  student at New York  University  and Johns
Hopkins University.

Meetings of the Board of Directors

      The Board of Directors of SIGA held eleven  meetings  during 2006.  During
2006, one director,  Dr. Mehmet C. Oz,  attended fewer than 75% of the aggregate
of the meetings of the Board of Directors  and  committees  thereof,  upon which
such  director  served  during the  period  for which he has been a director  or
committee  member.  In  addition,  actions  were taken  during 2006 by unanimous
written consent of the directors.

      Those members of the Board of Directors who are  independent as defined by
Rule 4200 of the NASD Marketplace Rules (the  "Independent  Directors") are also
required,  pursuant  to  Rule  4350(c)(2)  of the  NASD  Marketplace  Rules,  to
regularly convene executive  sessions where only such Independent  Directors are
present. Such meetings may be in conjunction with  regularly-scheduled  meetings
of the  Board of  Directors.  Each  member  of the  Board of  Directors  is also
expected to attend the annual meeting of stockholders of SIGA.  Seven members of
the Board of Directors attended SIGA's 2006 annual meeting of stockholders.

Committees of the Board of Directors

      The Board of  Directors  currently  has,  and  appoints  the  members  of,
standing Audit, Compensation and Nominating and Corporate Governance Committees.
Each member of the Audit,  Compensation and Nominating and Corporate  Governance
Committees is an Independent  Director.  Each of these  committees has a written
charter  approved by the Board of the  Directors  in March 2004.  A copy of each
charter  is  posted on  SIGA's  website  at  www.siga.com  under the  "Corporate
Governance" section.

      Audit  Committee.  The  Audit  Committee,   which  currently  consists  of
directors Paul G. Savas,  Judy S. Slotkin and James J. Antal,  held ten meetings
during 2006. The Board of Directors has  determined  that each of the members of
the Audit  Committee  is  "independent"  under the  applicable  laws,  rules and
regulations.  The Company has determined  that Mr. Savas is an "Audit  Committee
financial  expert"  within the  meaning of  Regulation  S-K  promulgated  by the
Securities  and  Exchange  Commission  (the  "SEC").  The  purpose  of the Audit
Committee is to assist the Board of Directors in the  oversight of the integrity
of the financial statements of SIGA, SIGA's compliance with legal and regulatory
matters, the independent  registered public accounting firm's qualifications and
independence,  and the  performance  of  SIGA's  independent  registered  public
accounting  firm. The primary  responsibilities  of the Audit  Committee are set
forth in its charter,  and include various matters with respect to the oversight
of SIGA's accounting and financial reporting process and audits of the financial
statements of SIGA on behalf of the Board of Directors. The Audit Committee also
selects the independent  registered public accounting firm to conduct the annual
audit of the financial  statements of SIGA;  reviews the proposed  scope of such
audit;  reviews  accounting and financial  controls of SIGA with the independent
registered  public  accounting  firm and our  financial  accounting  staff;  and
reviews and approves  transactions between us and our directors,  officers,  and
their  affiliates.  A copy of the Audit Committee charter is available on SIGA's
website at www.siga.com under the "Corporate  Governance" section.  Also see the
section of this proxy statement entitled "Report of the Audit Committee."


                                       5


      Compensation  Committee.  The  Compensation  Committee,   which  currently
consists of directors  Donald G.  Drapkin,  Paul G. Savas and Michael A. Weiner,
held one meeting during 2006. The Board of Directors has determined that each of
the members of the Compensation Committee is "independent" within the meaning of
the NASDAQ listing  standards.  The  Compensation  Committee  functions  include
reviewing  and  approving  the  compensation  and benefits for SIGA's  executive
officers,  administering  SIGA's stock plans and making  recommendations  to the
Board of Directors regarding these matters. A copy of the Compensation Committee
charter is  available on SIGA's  website at  www.siga.com  under the  "Corporate
Governance"  section.  Also see the  section  of this proxy  statement  entitled
"Compensation Discussion and Analysis."

      Nominating  and  Corporate  Governance   Committee.   The  Nominating  and
Corporate  Governance  Committee (the "Nominating  Committee"),  which currently
consists of directors Judy S. Slotkin, James J. Antal and Michael A. Weiner, was
formed in March 2004 and held three  meetings in 2006. On December 19, 2006, the
Board of  Directors  elected  Dr.  Weiner to replace  Mehmet C. Oz. The Board of
Directors has determined that each of the members of the Nominating Committee is
"independent" within the meaning of the NASDAQ listing standards. The Nominating
Committee is  responsible  for  searching for and  recommending  to the Board of
Directors potential nominees for director positions,  making  recommendations to
the  Board of  Directors  regarding  the size and  composition  of the  Board of
Directors and its committees,  monitoring the Board of Director's  effectiveness
and developing  and  implementing  SIGA's  corporate  governance  procedures and
policies. A copy of the Nominating and Corporate Governance Committee charter is
available on SIGA's website at  www.siga.com  under the  "Corporate  Governance"
section.

      In  selecting  candidates  for the  Board  of  Directors,  the  Nominating
Committee  begins by  determining  whether the incumbent  directors  whose terms
expire at the  annual  meeting  of  stockholders  desire  and are  qualified  to
continue  their service on the Board of Directors.  SIGA is of the view that the
continuing service of qualified  incumbents promotes stability and continuity of
the board,  giving SIGA the benefit of the  familiarity  and insight into SIGA's
affairs  that  its  directors  have  accumulated  during  their  tenure,   while
contributing  to the Board of Director's  ability to work as a collective  body.
Accordingly,  it is the  policy  of the  Nominating  Committee,  absent  special
circumstances, to nominate qualified incumbent directors who continue to satisfy
the  Nominating  Committee's  criteria for membership on the Board of Directors,
whom  the  Nominating   Committee  believes  will  continue  to  make  important
contributions to the Board of Directors and who consent to stand for re-election
and, if  re-elected,  to continue  their service on the Board of  Directors.  If
there are positions on the Board of Directors for which the Nominating Committee
will not be re-nominating an incumbent director, or if there is a vacancy on the
Board of Directors,  the Nominating  Committee will solicit  recommendations for
nominees from persons whom the  Nominating  Committee  believes are likely to be
familiar with qualified candidates,  including members of the Board of Directors
and management of SIGA. The Nominating  Committee may also engage a professional
search firm to assist in the identification of qualified candidates, but did not
do so in 2006. As to each  recommended  candidate that the Nominating  Committee
believes merits serious consideration,  the Nominating Committee will collect as
much  information,  including  without  limitation,  soliciting views from other
directors  and SIGA's  management  and having one or more  Nominating  Committee
members  interview  each such  candidate,  regarding  each candidate as it deems
necessary or appropriate  in order to make an informed  decision with respect to
such candidate.  Based on all available information and relevant considerations,
the Nominating  Committee will select,  for each  directorship  to be filled,  a
candidate  who,  in the view of the  Nominating  Committee,  is most  suited for
membership  on the  Board of  Directors.  In  making  its  selection,  SIGA will
evaluate  candidates  proposed by  stockholders  under  criteria  similar to the
evaluation  of other  candidates,  except  that  the  Nominating  Committee  may
consider,  as one of the factors in its  evaluation of  stockholder  recommended
nominees, the size and duration of the interest of the recommending  stockholder
or stockholder group in the equity of SIGA. This  consideration may also include
how long the  recommending  stockholder  intends to continue  holding its equity
interest in SIGA.

      The  Nominating  Committee has adopted a policy with regard to the minimum
qualifications  that must be met by a Nomination  Committee-recommended  nominee
for a position on SIGA's Board of  Directors,  which policy is described in this
paragraph.  The Nominating  Committee generally requires that all candidates for
the Board of Directors be of high personal integrity and ethical character.  The
Nominating Committee requires that candidates not have any interests that would,
in the view of the Nominating Committee, materially impair his or her ability to
(i) exercise  independent  judgment or (ii)  otherwise  discharge  the fiduciary
duties owed as a director to SIGA and its stockholders.  In addition, candidates
must be able to represent  fairly and equally all  stockholders  of SIGA without
favoring or advancing any particular  stockholder or other constituency of SIGA.
Candidates must have demonstrated achievement in one or more fields of business,
professional,   governmental,  communal,  scientific  or  educational  endeavor.
Candidates  are  expected  to have  sound  judgment  and a general  appreciation
regarding major issues facing public  companies of a size and operational  scope
similar  to  SIGA,  including  contemporary   governance  concerns,   regulatory
obligations of a public issuer,  strategic business  planning,  competition in a
global economy,  and basic concepts of corporate  finance.  Candidates must also
have, and be


                                       6


prepared  to  devote,  adequate  time to the  Board  and its  committees.  It is
expected  that,  taking into  account  their  other  business  and  professional
commitments,  including  their  service on the boards of other  companies,  each
candidate  will be available to attend  meetings of the Board and any committees
on  which  the  candidate  will  serve,  as well as  SIGA's  annual  meeting  of
stockholders.  SIGA also  requires  that at least a  majority  of the  directors
serving at any time on the Board are independent,  as defined under the rules of
the NASDAQ  stock  market and that at least three of the  directors  satisfy the
financial  literacy  requirements  required  for service on the Audit  Committee
under the rules of the NASDAQ stock market.

      The  Nominating  Committee  has  adopted  a  policy  with  regard  to  the
consideration of director candidates  recommended by stockholders,  the material
elements  of which  policy  are  described  in this  paragraph.  The  Nominating
Committee will consider recommendations for nomination for director submitted by
holders  of  SIGA's  shares  entitled  to  vote  generally  in the  election  of
directors.   The  Nominating   Committee  will  give   consideration   to  these
recommendations  for positions on the Board where the  Nominating  Committee has
not  determined  to  re-nominate  a  qualified  incumbent  director.  While  the
Nominating  Committee  has not  established  a minimum  number of shares  that a
stockholder  must  own in order  to  present  a  nominating  recommendation  for
consideration, or a minimum length of time during which the stockholder must own
its shares, the Nominating Committee may take into account the size and duration
of a  recommending  stockholder's  ownership  interest in SIGA.  The  Nominating
Committee  may also  consider  whether  the  stockholder  making the  nominating
recommendation   intends  to   maintain  an   ownership   interest  in  SIGA  of
substantially  the  same  size as at its  interest  at the  time of  making  the
recommendation.  The Nominating Committee may refuse to consider recommendations
of nominees  who do not satisfy the  minimum  qualifications  prescribed  by the
Nominating Committee for board candidates.

      The  Nominating  Committee  has  adopted  procedures  to  be  followed  by
stockholders  in  submitting  recommendations  of candidates  for director.  The
procedures  are posted on SIGA's  website at  www.siga.com  under the "Corporate
Governance" section, and described in this paragraph. A stockholder (or group of
stockholders)  wishing  to  submit a  nominating  recommendation  for an  annual
meeting of  stockholders  should try to ensure that it is  received by SIGA,  as
provided herein, not later than 120 calendar days prior to the first anniversary
of the date of the proxy statement for the prior annual meeting of stockholders.
All stockholder nominating  recommendations  should be in writing,  addressed to
"the  Nominating  and  Corporate  Governance  Committee"  care of  SIGA's  Chief
Financial Officer at SIGA's principal headquarters,  420 Lexington Avenue, Suite
408, New York, New York 10170.  Submissions  should be made by mail,  courier or
personal  delivery.  A nominating  recommendation  should be  accompanied by the
following information concerning each recommending stockholder:

   o  The name and address,  including  telephone  number,  of the  recommending
      stockholder;

   o  The number and class of SIGA's shares owned (beneficially or of record) by
      the  recommending  stockholder  and the time  period for which such shares
      have been held;

   o  A statement from the  stockholder as to whether the stockholder has a good
      faith  intention to continue to hold the reported  shares through the date
      of SIGA's next annual meeting of stockholders;

   o  Sufficient  information  about the  proposed  nominee  for the  Nominating
      Committee to make an informed decision regarding the qualifications of the
      proposed nominee;

   o  Any  relationship  between  the  proposed  nominee  and  the  recommending
      stockholder; and

   o  Such other information as the Nominating Committee may reasonably request.

The nominating recommendation must be accompanied by the consent of the proposed
nominee  to be  interviewed  by the  Nominating  Committee,  if  the  Nominating
Committee  chooses to do so in its discretion (and the recommending  stockholder
must  furnish the  nominee's  contact  information  for this  purpose),  and, if
nominated and elected, to serve as a director of SIGA.

Compensation Committee Interlocks and Insider Participation

      None.


                                       7


Code of Ethics

      SIGA has adopted a code of ethics and business conduct that applies to its
officers,  directors and  employees,  including  without  limitation,  our Chief
Executive  Officer,  Chief Financial Officer and Chief Scientific  Officer.  The
Code  of  Ethics  and  Business  Conduct  is  available  on  SIGA's  website  at
www.siga.com under the "Corporate Governance" section.

Stockholder Communications with the Board of Directors

      SIGA  stockholders may send  communications to the Board, any committee of
the Board or an individual director.  The process for so communicating is posted
on SIGA's website at www.siga.com under the "Corporate Governance" section.


                                       8


                          REPORT OF THE AUDIT COMMITTEE

      The members of the Audit  Committee  have been  appointed  by the Board of
Directors.  During the 2006 fiscal year, the Audit Committee consisted solely of
independent  directors,  as defined in Rule  4200(a)(15) of the NASD Marketplace
Rules. The Audit Committee operates under a written charter that was amended and
restated by the Board of  Directors  in March 2004 in order to assure  continued
compliance by SIGA with SEC and NASDAQ rules enacted in response to requirements
of the Sarbanes-Oxley Act.

      The Audit  Committee  assists the Board of  Directors  in  monitoring  the
integrity of SIGA's  financial  statements,  the independent  registered  public
accounting  firm's  qualifications  and  independence,  the  performance  of the
independent  registered  public accounting firm, and the compliance by SIGA with
legal and regulatory requirements. Management is responsible for SIGA's internal
controls and the financial reporting process. The independent  registered public
accounting  firm is responsible  for  performing an independent  audit of SIGA's
financial  statements in accordance with generally  accepted auditing  standards
and for  issuing a report on those  financial  statements.  The Audit  Committee
monitors and oversees these processes.

      In this  context,  the Audit  Committee  has  reviewed and  discussed  the
audited  financial  statements  for  the  year  ended  December  31,  2006  with
management and with  PricewaterhouseCoopers  LLP, SIGA's independent  registered
public    accounting    firm.   The   Audit   Committee   has   discussed   with
PricewaterhouseCoopers  LLP the matters required to be discussed by Statement on
Auditing  Standards No. 61, as amended  (Communications  with Audit Committees),
which includes,  among other items,  matters related to the conduct of the audit
of SIGA's annual financial statements.

      The Audit  Committee  has also  received the written  disclosures  and the
letter from  PricewaterhouseCoopers LLP required by Independence Standards Board
Standard  No.  1  (Independence  Discussions  with  Audit  Committees)  and  has
discussed with  PricewaterhouseCoopers  LLP the issue of their independence from
SIGA and management. In addition, the Audit Committee has considered whether the
provision of non-audit services by the independent  registered public accounting
firm in 2006 is compatible with  maintaining the auditors'  independence and has
concluded that it is.

      Based on its review of the audited  financial  statements  and the various
discussions  noted  above,  the  Audit  Committee  recommended  to the  Board of
Directors  that the audited  financial  statements  be included in SIGA's Annual
Report on Form 10-K for the year ended  December 31, 2006.  The Audit  Committee
has also  recommended,  subject to  stockholder  ratification,  the selection of
SIGA's  independent  registered  public  accounting  firm  for the  year  ending
December 31, 2007.

      The members of the Audit Committee are Paul G. Savas,  Judy S. Slotkin and
James J.  Antal,  none of whom is or,  during the  fiscal  year  2006,  was,  an
employee of SIGA.

                                  Respectfully submitted by the Audit Committee,
                                  Paul G. Savas, Chairman
                                  James J. Antal
                                  Judy S. Slotkin


                                       9


             COMPENSATION COMMITTEE REPORT ON EXECUTIVE COMPENSATION

      The Compensation Committee, comprised of independent directors, has:

(1) reviewed and discussed the Compensation  Discussion and Analysis included in
this proxy statement with management; and

(2) based on the review and discussions  referred to in paragraph (1) above, the
Compensation   Committee   recommended  to  the  Board  of  Directors  that  the
Compensation  Discussion  and  Analysis  be  included  in  the  Company's  proxy
statement relating to the 2007 Annual Meeting of shareholders.

      During the year ended  December 31, 2006, the  Compensation  Committee was
comprised of Donald G. Drapkin,  Paul G. Savas and Mehmet C. Oz. On December 19,
2006, the Board of Directors  elected  Michael A. Weiner to replace Mehmet C. Oz
on the Committee.  The events described in this report occurred after Michael A.
Weiner replaced Mehmet C. Oz on the Compensation Committee.


                        Respectfully submitted by the Compensation Committee,
                        Donald G. Drapkin
                        Paul G. Savas
                        Michael A. Weiner


                                       10


         SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

      The  following  tables  set  forth  certain   information   regarding  the
beneficial  ownership of SIGA's  voting  securities  as of March 15, 2007 of (i)
each person  known to SIGA to  beneficially  own more than 5% of the  applicable
class of voting  securities,  (ii) each  director and director  nominee of SIGA,
(iii) each Named Executive Officer and (iv) all directors and executive officers
of SIGA as a group. As of March 15, 2007, a total of 32,714,394 shares of Common
Stock were  outstanding.  Each share of Common  Stock is entitled to one vote on
matters  on which  holders  of Common  Stock are  eligible  to vote.  The column
entitled  "Percentage of Total Voting Stock Outstanding" shows the percentage of
total voting stock beneficially owned by each listed party.

      The  number  of  shares  beneficially  owned  is  determined  under  rules
promulgated by the Securities and Exchange  Commission,  and the  information is
not necessarily  indicative of beneficial ownership for any other purpose. Under
those rules, beneficial ownership includes any shares as to which the individual
has sole or shared  voting power or  investment  power and also any shares which
the  individual  has the right to  acquire  within  60 days of March  15,  2007,
through the exercise or conversion of any stock  option,  convertible  security,
warrant or other right. Unless otherwise indicated,  each person or entity named
in the table has sole voting  power and  investment  power (or shares that power
with that person's spouse) with respect to all shares of capital stock listed as
owned by that person or entity.

                            Ownership of Common Stock

      The  following  tables  set  forth  certain   information   regarding  the
beneficial  ownership of SIGA's  voting  securities  as of March 15, 2007 of (i)
each person  known to SIGA to  beneficially  own more than 5% of the  applicable
class of voting  securities,  (ii) each  director and director  nominee of SIGA,
(iii) each Named Executive Officer,  and (iv) all directors and officers of SIGA
as a group.  As of March 15, 2007, a total of 32,714,394  shares of common stock
were outstanding.  Each share of common stock is entitled to one vote on matters
on  which  common  stockholders  are  eligible  to  vote.  The  column  entitled
"Percentage  of Total Voting  Stock" shows the  percentage of total voting stock
beneficially owned by each listed party.



                                                                            Percentage of          Percentage of
Name and Address of                              Amount of Beneficial       Common Stock            Total Voting
Beneficial Owner (1)                                Ownership (2)            Outstanding         Stock Outstanding
--------------------                             ---------------------     ----------------     --------------------
                                                                                          
Beneficial Holders

MacAndrews & Forbes Inc. (3)
35 East 62nd Street
New York, NY 10021........................             5,620,771(4)           16.3%                   16.3%

TransTech Pharma, Inc.
4170 Mendenhall Oaks Parkway
High Point, NC 27265......................             5,296,634(5)           15.3%                   15.3%

Bernard L. Kasten Jr., M.D.(19)
8622 Twilight Tear Lane
Cincinnati, OH 45249......................             1,672,360(20)           4.91%                   4.91%

Officers and Directors

Donald G. Drapkin (6) (14)
35 East 62nd Street
New York, NY 10021.........................            1,818,326(7)            5.3%                    5.3%

James J. Antal
30952 Steeplechase Dr.
San Juan Capistrano, CA 94704..............               56,154(8)               *                      *

Judy S. Slotkin (18)
888 Park Avenue
NY, NY 10021...............................               98,849(9)               *                      *



                                       11



                                                                                               
Thomas E. Constance
1177 Avenue of the Americas,
New York, NY 10036..........................            273,467(10)               *                      *

Scott M. Hammer, M.D.
161 Fort Washington Ave.
New York, NY 10032                                       25,000(11)               *                      *

Adnan M. Mjalli, Ph.D. (14)
4170 Mendenhall Oaks Parkway, Suite 110
High Point, NC 27265.........................            45,000(12)               *                      *

Mehmet C. Oz, M.D.
177 Fort Washington Ave
New York, NY 10032...........................           145,000(13)               *                      *

Eric A. Rose, M.D. (14)
35 East 62nd Street
New York, NY 10021...........................           810,090(15)              2.4%                   2.4%

Paul G. Savas (14)
35 East 62nd Street
New York, NY 10021..........................             71,664(16)               *                      *

Michael A. Weiner, M.D.
161 Fort Washington Ave.
New York, NY
10032.........................................         132,500(13)                *                      *

Thomas N. Konatich............................         545,000(17)               1.6%                   1.6%

Dennis E. Hruby, Ph.D. .......................         625,000(17)               1.9%                   1.9%

All Executive Officers and Directors as a
group (twelve persons)........................       4,646,050(21)              12.6%                  12.6%


-------------
*     Less than 1%

(1)   Unless otherwise indicated the address of each beneficial owner identified
      is 420 Lexington Avenue, Suite 408, New York, NY 10170.

(2)   Unless  otherwise  indicated,  each person has sole  investment and voting
      power with respect to the shares indicated.  For purposes of this table, a
      person or group of persons is deemed to have "beneficial ownership" of any
      shares as of a given  date  which  such  person  has the right to  acquire
      within 60 days after such date.  For purposes of computing the  percentage
      of outstanding  shares held by each person or group of persons named above
      on a given date,  any security  which such person or persons has the right
      to acquire within 60 days after such date is deemed to be outstanding  for
      the  purpose of  computing  the  percentage  ownership  of such  person or
      persons,  but is not deemed to be outstanding for the purpose of computing
      the percentage ownership of any other person.

(3)   MacAndrews & Forbes Inc. is a direct wholly-owned subsidiary of MacAndrews
      & Forbes Holdings Inc., a holding company whose sole stockholder is Ronald
      O. Perelman.

(4)   Includes  1,764,206  shares of common  stock  issuable  upon  exercise  of
      warrants.

(5)   Includes  1,824,412  shares of common  stock  issuable  upon  exercise  of
      warrants.

(6)   Mr.  Drapkin  is a  director  and Vice  Chairman  of  MacAndrews  & Forbes
      Holdings  Inc.  and  MacAndrews  & Forbes Inc. and a director of TransTech
      Pharma.

(7)   Includes 1,145,000  shares of common  stock  issuable  upon  exercise  of
      options,  shares of common stock underlying a warrant to purchase up to
      347,826  shares of common  stock and shares of common  stock  underlying a
      warrant to  purchase  up to 30,500  shares of common  stock (the  "Drapkin
      September 2001 Investor  Warrant").  However,  the Drapkin  September 2001
      Investor  Warrant  provides that,  with certain limited  exceptions,  such
      warrant is not exercisable if, as a result of such exercise, the number of
      shares  of  common  stock  beneficially  owned  by  Mr.  Drapkin


                                       12


      and his affiliates  (other than shares of common stock which may be deemed
      beneficially owned through the ownership of the unexercised portion of the
      Drapkin  September  2001  Investor  Warrant)  would  exceed  9.99%  of the
      outstanding  shares of common  stock.  Does not  include  shares of common
      stock that Mr. Drapkin,  as a director and Vice Chairman of Mafco Holdings
      Inc. and  MacAndrews & Forbes or as director of TransTech  Pharma,  may be
      deemed  to  beneficially  own  and  as  to  which  Mr.  Drapkin  disclaims
      beneficial ownership.

(8)   Includes 45,000 shares of common stock issuable upon exercise of options.

(9)   Includes 45,000 shares of common stock issuable upon exercise of options.

(10)  Includes  12,200  shares  issuable  upon  exercise of warrants and 245,000
      shares of common stock issuable upon exercise of options.

(11)  Includes 25,000 shares issuable upon exercise of options.

(12)  Includes  45,000 shares of common stock issuable upon exercise of options.
      Does not include shares of common stock that Dr. Mjalli,  as a director of
      TransTech  Pharma,  may be deemed to beneficially  own and as to which Dr.
      Mjalli disclaims beneficial ownership.

(13)  Includes  12,500  shares  issuable  upon  exercise of warrants and 120,000
      shares issuable upon exercise of options.

(14)  Dr. Rose, Dr. Mjalli, Mr. Drapkin and Mr. Savas are directors of TransTech
      Pharma.

(15)  Includes  88,610 shares of common stock issuable upon exercise of warrants
      and 620,000 shares of common stock issuable upon exercise of options. Does
      not  include  shares of common  stock  that Dr.  Rose,  as a  director  of
      TransTech  Pharma,  may be deemed to beneficially  own and as to which Dr.
      Rose disclaims beneficial ownership.

(16)  Includes  9,303 shares of common stock  issuable upon exercise of warrants
      and 45,000 shares issuable upon exercise of options.

(17)  Neither of Messrs.  Konatich  and Hruby own  shares of common  stock.  All
      shares listed as beneficially owned by each of Messrs.  Konatich and Hruby
      are shares issuable upon exercise of stock options.

(18)  Includes 45,000 shares issuable upon exercise of options and 18,244 shares
      issuable upon exercise of warrants.

(19)  Dr.  Kasten  became our Chief  Executive  Officer in the third  quarter of
      2004. Dr. Kasten resigned as Chief Executive  Officer of SIGA effective as
      of April 30, 2006.

(20)  Includes  1,350 shares of common stock  issuable upon exercise of warrants
      and 1,310,000 shares of common stock issuable upon exercise of options

(21)  See footnotes (6)-(20).


                                       13


                                   MANAGEMENT

Officers

      The  following  table sets forth certain  information  with respect to the
Named Executive Officers of SIGA:



         Name                                   Age      Position
         ----                                   ---      --------
                                                   
         Bernard L. Kasten Jr. M.D. (1)         60       Director, Chief Executive Officer
         Thomas N. Konatich (2)                 61       Vice President, Chief Financial Officer, Secretary and
                                                         Treasurer
         Dennis E. Hruby, Ph.D.                 54       Vice President, Chief Scientific Officer
         Eric A. Rose, M.D.                     54       Chief Executive Officer and Chairman of the Board


      (1)   Dr.  Kasten  became  Chief  Executive  Officer on July 2, 2004.  Dr.
            Kasten resigned as Chief  Executive  Officer of SIGA effective as of
            April 30, 2006. Dr. Kasten was a director of SIGA until December 19,
            2006.

      (2)   Mr.  Konatich was  appointed to serve in an  additional  capacity as
            Acting  Chief  Executive  Officer  effective  May  1,  2006  through
            February 28, 2007.

      Bernard L.  Kasten,  Jr.,  M.D.  has been a director of SIGA since May 23,
2003 and was Chief  Executive  Officer  from the third  quarter of 2004  through
April 30,  2006.  Prior to becoming  Chief  Executive  Officer of SIGA and since
February 2002, Dr. Kasten has been Vice  President,  Medical  Affairs of MedPlus
Inc., a healthcare information technology company and a wholly-owned  subsidiary
of Quest  Diagnostics,  Inc., a  diagnostic  testing,  information  and services
company.  Since 1975,  Dr.  Kasten has been a Diplomat of the American  Board of
Pathology with a sub-specialty  certification 1976 in Medical Microbiology.  Dr.
Kasten's staff  appointments have included service in the Division of Laboratory
Services at The Cleveland Clinic; Associate of Pathology and Laboratory Services
at the  Bethesda  Hospital  Systems  in  Cincinnati,  Ohio and Chief  Laboratory
Officer at Quest  Diagnostics  Incorporated.  Dr. Kasten was a founder of Plexus
Vaccine Inc., a vaccine company of which SIGA acquired  substantially all of the
assets in May 2003.  Dr.  Kasten is also a director of Seracare  Life  Sciences,
Inc. Dr. Kasten is an author of "Infectious Disease Handbook" 5th Edition, 2003,
Lexi-Comp Inc.

      Thomas N. Konatich has served as Vice President,  Chief Financial  Officer
and Treasurer  since April 1, 1998.  He was named  Secretary of SIGA on June 29,
2001. During the periods from October 5, 2001 until July 2, 2004 and May 1, 2006
until February 28, 2007, Mr.  Konatich was our Acting Chief  Executive  Officer.
From November 1996 through March 1998, Mr.  Konatich  served as Chief  Financial
Officer and a director of  Innapharma,  Inc.,  a privately  held  pharmaceutical
development  company.  From 1993 through  November 1996, Mr.  Konatich served as
Vice President and Chief Financial  Officer of Seragen,  Inc., a publicly traded
biopharmaceutical development company. Mr. Konatich has an MBA from the Columbia
Graduate School of Business.

      Dennis E. Hruby,  Ph.D.  has served as Vice  President - Chief  Scientific
Officer since June 2000. From April 1, 1997 through June 2000, Dr. Hruby was our
Vice  President of Research.  From  January 1996 through  March 1997,  Dr. Hruby
served as a senior  scientific  advisor to SIGA.  Dr.  Hruby is a  Professor  of
Microbiology at Oregon State  University,  and from 1990 to 1993 was Director of
the Molecular and Cellular Biology Program and Associate  Director of the Center
for Gene Research and Biotechnology.  Dr. Hruby specializes in virology and cell
biology  research,  and  the use of  viral  and  bacterial  vectors  to  produce
recombinant  vaccines.  He is a member of the American Society of Virology,  the
American  Society  for  Microbiology  and a fellow of the  American  Academy  of
Microbiology.  Dr. Hruby received a Ph.D. in microbiology from the University of
Colorado Medical Center and a B.S. in microbiology from Oregon State University.

                      COMPENSATION DISCUSSION AND ANALYSIS

Overview

      The  Compensation  Committee of the Board of Directors is responsible  for
implementing  the Board's  directives  relating to the compensation of our named
executive  officers,  as well as our other key  employees.  In this regard,  the
Compensation Committee has the responsibility to establish a compensation policy
for  officers  and key  employees  designed  to (i)  attract and retain the best
possible  executive  talent;  (ii) tie  annual  and  long  term  cash and  stock
incentives to  achievement of measurable  corporate and  individual  performance
objectives;  and (iii) provide competitive  compensation to our officers and key
employees  to align  executives'  incentives  with the  creation of  stockholder
value.


                                       14


      As a  general  matter,  the  compensation  policy  for  officers  and  key
employees includes:

            o     base salary,  which is determined on an annual or  semi-annual
                  basis

            o     annual or other time-based cash incentive compensation, and

            o     long-term  incentive  compensation  in  the  forms  of  equity
                  participation awards.

      This  section   discusses   the   principles   underlying   our  executive
compensation  policies,  our decisions to date and the principles that we expect
to use in coming years.

Our Named Executive Officers

      For 2006, our Named Executive Officers and their titles were:



Name                        Title
                         
Dr. Bernard L. Kasten       Chief Executive Officer(1)
Thomas N. Konatich          Acting Chief Executive  Officer(2) & Vice  President, Chief Financial Officer,
                            Secretary and Treasurer
Dr. Dennis E. Hruby         Chief Scientific Officer and Vice President
Dr. Eric A. Rose            Chief Executive Officer(3) and Chairman of the board


      (1)   From July 2, 2004 through April 30, 2006.

      (2)   From May 1, 2006 through February 28, 2007.

      (3)   On March 1,  2007,  Dr.  Eric A. Rose  became  our  Chief  Executive
            Officer.

Our Executive Compensation Decision Process

Overview

      Our  Compensation  Committee  reviews and approves on a periodic basis the
corporate  goals and objectives with respect to the  compensation  for the chief
executive officer and other executive officers.

Role of Executive Officers in Setting Compensation Decisions

      Regarding  most  compensation  matters,  the Chief  Executive  Officer has
historically provided  recommendations to the Compensation  Committee relying on
his personal experience with respect to evaluating the contribution of our other
executive  officers.  We anticipate  that Dr. Eric A. Rose,  currently our Chief
Executive  Officer and  Chairman  of the Board will be involved in  compensation
recommendations,   with  input  from  our  Chief  Financial  Officer  and  Chief
Scientific  Officer,  as it relates to the  compensation of other key employees.
The Compensation Committee considers,  but retains the right to reject or modify
such recommendations.  Although the Chief Executive Officer may attend a portion
of the meetings of the Compensation  Committee,  neither he nor any other member
of  management  may be present  during  executive  sessions of the  Compensation
Committee.  Moreover,  the  Chief  Executive  Officer  may not be  present  when
decisions with respect to his  compensation are made. The Committee has used, on
more than one occasion, a third party compensation consultant.

Compensation Advisors

      The  Compensation  Committee  has the  authority  to  retain  compensation
consultants to advise the Compensation  Committee as it deems necessary to carry
out its duties.

Competitive Market Analysis and Benchmarking

      In reviewing and  recommending  the  compensation  of the Chief  Executive
Officer and other executive officers,  the Compensation  Committee considers the
compensation   awarded  to  officers  of  similarly  situated   companies,   our
performance, the individuals' performance, compensation given to our officers in
past years or any other factor the Compensation Committee deems appropriate.


                                       15


Evaluations

      The Compensation  Committee evaluates at least once a year the performance
of our  officers  and  other  key  employees  in light of goals  and  objectives
established by the Committee and based upon these  evaluations the  Compensation
Committee recommends to the full Board of Directors, the annual compensation for
our officers and key  employees,  including  base salary,  bonus,  incentive and
equity compensation.

Our Compensation Philosophy and Program Objectives

      The  overall  objectives  of the  Company's  compensation  program  are to
attract  and  retain the best  possible  executive  talent,  to  motivate  these
executives to achieve the goals inherent in the Company's business strategy,  to
maximize the link between  executive and stockholder  interests  through a stock
option  plan  and to  recognize  individual  contributions  as well  as  overall
business  results.  To achieve  these  objectives,  the Company has developed an
overall  compensation  strategy  and  specific  compensation  plans  that  tie a
substantial portion of an executive's compensation to performance.

Our Executive Compensation Program

Overview

      The key elements of the Company's  compensation  program  consist of fixed
compensation  in the form of base salary,  and the  discretion to award variable
compensation  in the forms of annual  incentive  compensation  and stock  option
awards.  The  Compensation  Committee's  policies  with respect to each of these
elements are discussed  below.  In addition,  while the elements of compensation
described below are considered separately, the Compensation Committee takes into
account the full compensation  package offered by the Company to the individual,
including  pension  benefits,  insurance  and  other  benefits,  as  well as the
programs described below.

Base Salary

      The compensation  philosophy of the Company is to maintain  executive base
salary at a  competitive  level to enable  the  Company  to  attract  and retain
executives and key employee talent needed to accomplish the Company's  goals. In
determining  the appropriate  base salary levels and, to a lesser extent,  other
compensation  elements,  the  Compensation  Committee  considers  the  scope  of
responsibility, prior experience and past accomplishments, as well as historical
practices  within the Company.  Economic and business  conditions  affecting the
Company  are  also  considered.   The  Compensation   Committee  also  considers
historical levels of salary paid by the Company as well as the provisions in the
various executive's  employment contracts with the Company,  which contracts are
more fully discussed elsewhere in this proxy statement.

      Periodic  adjustments  in base salary may be merit  based with  respect to
individual  performance  or tied to the Company's  financial  condition or other
competitive factors. The Compensation Committee takes into account the effect of
any corporate  transactions that have been consummated  during the relevant year
and, where appropriate, also considers non-financial performance measures. These
include the Company's market share,  scientific developments and improvements in
relations with employees and investors.

      For Mr. Konatich and Dr. Hruby, we paid as base salary in 2006 the amounts
required under their employment agreements.  These amounts were reviewed and set
by our Compensation Committee. These base salary levels reflect our Compensation
Committee's  subjective  judgment,  which  took into  account  each  executive's
respective  position and tenure,  our present needs, the executive's  individual
performance, achievements and prior contributions.

      For Dr.  Kasten,  we paid the amounts  required by various  agreements  to
which we and he are parties and which,  in all  instances,  where  reviewed  and
approved by the Compensation Committee.

Annual Incentive Compensation

      The  Compensation  Committee,  in  its  discretion,   may  establish  cash
incentive  programs and otherwise  award  bonuses to executive  officers and key
employees.  Annual incentive  compensation to our executive  officers is payable
pursuant  to  contractual  provisions  with  certain  executives  which  provide
eligibility  to receive  discretionary  bonuses,  in the sole  discretion of the
Board of Directors  based on the executives  performance,  economic and business
conditions  affecting the Company,  and the financial  condition of the Company.
The Compensation  Committee makes recommendations to the Board of Directors with
respect  to  such  amounts.  In  addition,   Dr.  Hruby  and  Mr.  Konatich  are
contractually  entitled to certain guaranteed cash bonus payments each year. The
annual incentive  compensation earned by the executives with respect to 2006 was
discretionary and determined by the Compensation  Committee. We believe that the
annual  incentive  bonuses  motivate and encourage our executives to fulfill our
objectives and provide us with the opportunity to recognize superior  individual
performance.


                                       16


      For 2006,  both Mr.  Konatich and Dr. Hruby were  eligible for annual cash
bonuses. In the case of Mr. Konatich,  his annual cash bonus was $60,000 and for
Dr. Hruby his annual cash bonus was $62,500.

Long-Term Incentive Awards

      The  Compensation  Committee  believes that  granting  stock options on an
ongoing basis provides  officers and key employees with strong economic interest
in maximizing stock price  appreciation  over the long term. We believe that the
practice of granting  stock options is critical to retaining and  recruiting the
key talent  necessary at all employee  levels to ensure the Company's  continued
success.  This element of  compensation  is governed by the Amended and Restated
1996  Incentive  and  Non-Qualified  Stock Option Plan (the "Option  Plan") that
provides for grants of incentive stock options and  non-qualified  stock options
to our executives,  directors and key employees. The Option Plan is administered
by our  Compensation  Committee,  which  determines  persons to be granted stock
options,  the amount of stock options to be granted to each such person, and the
terms and  conditions  of any stock  options as  permitted  under the Plan.  The
exercise  price of stock  options is set by the  Compensation  Committee and has
been at a price at least  equal to the market  price of the common  stock on the
date of the grant. The options  therefore do not have any value to the executive
unless the market  price of the  common  stock  rises,  which  ensures  that the
interests of our executives are aligned with those of our shareholders.  Through
these  option  grants,  we seek to emphasize  the  importance  of improving  the
performance of our stock price, increasing shareholder value over the long-term.

      Both Incentive  Options and Nonqualified  Options may be granted under the
Option Plan.  An Incentive  Option is intended to qualify as an incentive  stock
option  within the meaning of Section 422 of the Internal  Revenue Code of 1986,
as amended (the "Code").  As such,  any Incentive  Option granted under the Plan
will have an exercise  price of not less than 100% of the fair  market  value of
the  shares on the date on which  such  option is  granted.  With  respect to an
Incentive  Option  granted  to an  employee  who owns more than 10% of the total
combined  voting  stock of SIGA or of any  parent  or  subsidiary  of SIGA,  the
exercise price for such option must be at least 110% of the fair market value of
the shares subject to the option on the date the option is granted.

      In determining the size of an option grant to a named  executive  officer,
the  Compensation  Committee  considers  not only  competitive  market  factors,
changes  in   responsibility   and  the  executive   officers'   achievement  of
pre-established  goals,  but  also  the  number,  term and  vesting  of  options
previously granted to the officer. The Compensation  Committee may also consider
the total compensation package or changes made thereto, when determining whether
to make an option award.

      During the year ended December 31, 2006 the Compensation Committee did not
authorize awards of options to the officers of the Company.

Additional Benefits and Perquisites

      Our officers and key employees are entitled to  participate in the benefit
plans which are generally available to all employees,  including health, dental,
life, and accidental  disability.  For each of these benefit plans,  the Company
makes contributions to the premiums paid to the plans. The Company also offers a
401(k)  defined  contribution  plan,  however,  the  Company  does  not make any
contribution  to the 401(k) plan. In each case, we provide these benefits to our
executive officers on the same basis as our other employees.

Severance and Change-in-Control Agreements

      Finally, we also provide some of our executive officers with severance and
change-in-control  arrangements in their employment  contracts.  We believe that
severance  and  change  of  control  packages  are a  common  characteristic  of
compensation  for key  executive  officers.  They are  intended  to provide  our
executive officers with a sense of security in making the commitment to dedicate
their  professional  career to our  success.  Due to our size  relative to other
public  companies  and our  operating  history,  we believe that  severance  and
change-in-control  arrangements  are  necessary  to help us  attract  and retain
necessary  skilled  and  qualified  executive  officers  to continue to grow our
business. As described elsewhere in this proxy statement, Dr. Kasten, our former
Chief  Executive  Officer,  entered  into an  arrangement  with the  Company  in
connection with his resignation.

Our Compensation Policies

Section 162(m) Policy

      The  Compensation  Committee  attempts  to ensure  full  deductibility  of
compensation  notwithstanding  the  limitation on the  deductibility  of certain
compensation  in excess of one million dollars under Section 162(m) of the Code.


                                       17


The  Company's  stock  options are  designed  so as to cause  stock  options and
bonuses  granted  there under to be exempt  from the  limitations  contained  in
Section 162(m) of the Code.

Common Share Ownership Requirements

      While  we have not  adopted  a  formal  written  policy  on  common  share
ownership  requirements,  part of our  compensation  philosophy  involves common
share ownership by our executive  officers,  because we believe that it helps to
align  their  financial  interests  with  those  of our  shareholders.  We  also
recognize,  on the other hand,  that our executive  officers cannot acquire more
than 10% of our common shares without  triggering  adverse tax consequences.  In
addition,  we expect our  executive  officers to abide by the  provisions of our
2004 Policy on Confidential Information and Insider Trading.

Timing of Awards

      Our Compensation  Committee has the authority to issue equity awards under
our Amended and Restated 1996 Incentive and Non-Qualified Option Plan. We expect
that the  Compensation  Committee  will continue  making  ongoing  annual option
awards to our executive officers and key employees.  The Compensation  Committee
strives  to ensure  that any  award is made in such a manner  to avoid  even the
appearance of manipulation because of its award date.


                                       18


Summary Compensation Table

      The  following  table sets forth the total  compensation  of the Company's
Named Executive  Officers for the fiscal year ended December 31, 2006. The Named
Executive  Officers are the Company's Chief Executive  Officer,  Chief Financial
Officer,  Chief Scientific  Officer and the three other most highly  compensated
officers whose total compensation exceeded $100,000.

                           Summary Compensation Table



                                                                                             Change in
                                                                                           Pension Value
                                                                                                and
                                                                               Non-Equity   Nonqualified
                                                                               Inventive      Deferred         All
                                                           Stock    Option        Plan      Compensation      Other
                                      Salary      Bonus    Awards   Awards    Compensation    Earnings     Compensation     Total
Name and Principal Position    Year     ($)        ($)       ($)      ($)          ($)           ($)            ($)          ($)
                               ----   ------     -------   ------  ---------  ------------  ------------   ------------   ---------
                                                                                               
Bernard L. Kasten, M.D.        2006    83,333         --      --          --        --            --         94,792         178,125
Chief Executive Officer (1)    2005   250,000         --      --          --        --            --             --         250,000
                               2004   113,636         --      --   2,556,000        --            --             --       2,669,636

Thomas N. Konatich             2006   233,333    117,500      --          --        --            --             --         350,833
Chief Financial Officer (2)    2005   230,000     35,000      --          --        --            --             --         265,000
                               2004   218,485     50,000      --      86,865        --            --             --         355,350

Dennis E. Hruby, Ph.D.         2006   229,166    174,500      --          --        --            --             --         403,666
Chief Scientific Officer       2005   225,000    112,500      --          --        --            --             --         337,500
                               2004   213,363     63,000      --     119,910        --            --             --         396,273

Eric A. Rose, M.D.             2006        --         --      --          --        --            --             --              --
Chief Executive Officer (3)    2005        --         --      --          --        --            --             --              --
                               2004        --         --      --          --        --            --             --              --


(1)  Dr. Kasten became Chief Executive Officer on July 2, 2004. His annual
     salary was $250,000. Dr. Kasten resigned as Chief Executive Officer of SIGA
     effective as of April 30, 2006.

(2)  Mr. Konatich was appointed to serve in an additional capacity as Acting
     Chief Executive Officer effective from May 1, 2006 through February 28,
     2007.

(3)  Dr. Rose became Chief Executive Officer on March 1, 2007.

Salary

      The amounts  reported in the "Salary" column above represent base salaries
paid to each of the Named Executive Officers for the fiscal year ended 2006.

Bonus

      The  amounts  reported  in the  "Bonus"  column  above for the year  ended
December 31,  2006,  include  bonus which was paid in 2006 and bonus  accrued as
compensation for 2006 and paid in 2007.

Option Awards

      As of January 1, 1996,  we adopted our 1996  Incentive  and  Non-Qualified
Stock Option Plan. An amendment and  restatement  of such plan, as amended,  was
adopted on May 3, 2001 and was further refined by the Board of Directors on June
29, 2001 (the "Plan").  The Plan was approved by our  stockholders  at an annual
meeting on August 15,  2001,  and amended on January 8, 2004,  to  increase  the
maximum  number of shares of common stock  available for issuance under the Plan
to 10,000,000.  Stock options may be granted to key employees,  consultants  and
outside directors pursuant to the Plan. The Plan was amended again at our annual
meeting on May 26,  2005,  when our  stockholders  voted to increase the maximum
number of shares of common  stock  available  for  issuance  under the Plan from
10,000,000 to 11,000,000.


                                       19


      The Plan is administered by our  Compensation  Committee which  determines
persons to be granted stock  options,  the amount of stock options to be granted
to each such  person,  and the  terms and  conditions  of any stock  options  as
permitted under the Plan. The members of the Compensation  Committee are Michael
A. Weiner,  M.D.,  Paul G. Savas and Donald G. Drapkin.  See  "Committees of the
Board of Directors" above for more information.

      Both Incentive  Options and Nonqualified  Options may be granted under the
Plan.  An Incentive  Option is intended to qualify as an incentive  stock option
within the  meaning of Section  422 of the  Internal  Revenue  Code of 1986,  as
amended (the "Code").  Any Incentive  Option granted under the Plan will have an
exercise  price of not less than 100% of the fair market  value of the shares on
the date on which such option is granted.  With respect to an  Incentive  Option
granted to an employee who owns more than 10% of the total combined voting stock
of SIGA or of any parent or  subsidiary  of SIGA,  the  exercise  price for such
option must be at least 110% of the fair market  value of the shares  subject to
the option on the date the option is granted.

      The Plan,  as amended,  provides  for the  granting of options to purchase
11,000,000  shares of common stock, of which 7,546,145  options were outstanding
as of December 31, 2006.


                                       20


All Other Compensation

      The amount reported in the "All Other Compensation" reflects payments made
to Dr. Kasten under his Separation  Agreement with the Company,  dated March 31,
2006.

Grants of Plan Based Awards

      No options or other grants of plan based  awards were  granted  during the
year ended December 31, 2006 to any named executive officer in their capacity as
such; however, Dr. Eric A. Rose, who became our Chief Executive Officer on March
1, 2007,  received an award of an option to purchase 10,000 shares of our common
stock on December  19, 2006,  in his capacity as a director of SIGA.  Please see
the section entitled  "Directors'  Compensation"  below for a description of Dr.
Rose's option award.

Employment Agreements

      We currently have  employment  agreements  with Dr. Rose, Mr. Konatich and
Dr. Hruby.  These agreements became effective as of March 1, 2007 in the case of
Dr.  Rose and January 22, 2007 in the case of Mr.  Konatich  and Dr.  Hruby.  In
fiscal  year  2006,  Mr.  Konatich  and Dr.  Hruby  were  employed  under  prior
employment  agreements  (which the current  agreements  amend and  restate).  In
addition,  we had an  employment  agreement  with  our  former  Chief  Executive
Officer, Dr. Bernard L. Kasten, during his term of employment.

      We have included below descriptions of the current  employment  agreements
and those in effect as of  December  31,  2006.  As we believe  that the current
agreements  are  the  most  relevant  for  an   understanding   of  the  current
arrangements  with our named  executive  officers,  we have included them first.
However,  we follow the  current  descriptions  with  descriptions  of the prior
agreements in place as of December 31, 2006, so that the relevant information is
available  for those  matters in this proxy  statement  that are  required to be
disclosed as of December 31, 2006.

Eric A. Rose - Chief Executive Officer

      On January 31, 2007, we entered into an employment agreement with Dr. Eric
A.  Rose,  M.D.,  pursuant  to which he  became  our  Chief  Executive  Officer,
effective as of March 1, 2007. The employment  agreement expires on February 29,
2008, and, unless either party provides thirty (30) days notice prior to the end
of the term,  shall  automatically  renew for  additional  one (1) year  periods
thereafter. Pursuant to the employment agreement, we agree to pay to Dr. Rose an
annual base salary of $400,000, subject to any cost of living adjustments as may
be approved by our Board.  Dr. Rose is also eligible to receive  bonus  payments
(in either  cash or stock  options)  as may be approved by the Board in its sole
discretion.  We may terminate his employment  agreement (with or without cause),
provided  that upon any  termination  by us without  cause  (including,  without
limitation,  termination without cause upon a change in control), or termination
by Dr. Rose for


                                       21


good reason,  we will be obligated to continue to pay Dr. Rose's base salary for
one year, and all stock options and other  stock-based  grants to Dr. Rose shall
immediately  and  irrevocably  vest  and  become  exercisable  upon  the date of
termination  and shall remain  exercisable for a period of not less than one (1)
year from the date of termination.  Further detail on our severance  obligations
to Dr. Rose,  including the definitions of "cause," "good reason" and "change in
control"  is  set  forth  below  under  the  heading  "Potential  Payments  Upon
Termination or Change-in-Control."

Thomas N. Konatich - Chief Financial Officer

      On January 22, 2007,  we entered  into an amended and restated  employment
agreement with Thomas N. Konatich,  our Chief Financial Officer,  which replaced
his prior  employment  agreement  (which agreement is described in the following
paragraph).  Mr.  Konatich  also  serves as our Vice  President,  Secretary  and
Treasurer,  and from May 1, 2006 through  February 28, 2007 served as our Acting
Chief Executive Officer. The current employment agreement expires on January 22,
2009, and, unless either party provides thirty (30) days notice prior to the end
of the term,  shall  automatically  renew for  additional  one (1) year  periods
thereafter.  Pursuant  to  the  employment  agreement,  we  agree  to pay to Mr.
Konatich  an annual  base  salary  of  $250,000,  subject  to any cost of living
adjustments  as may be  approved  by our  Board,  and an  annual  cash  bonus of
$60,000. Mr. Konatich is also eligible to receive such additional bonus payments
(in either  cash or stock  options)  as may be approved by our Board in its sole
discretion.  We may terminate his employment  agreement (with or without cause),
provided  that upon any  termination  by us without  cause  (including,  without
limitation,  termination without cause upon a change in control), or termination
by Mr.  Konatich  for good  reason,  we will be obligated to continue to pay Mr.
Konatich's  base  salary  for two (2)  years,  and all stock  options  and other
stock-based  grants to Mr. Konatich shall  immediately and irrevocably  vest and
become exercisable upon the date of termination and shall remain exercisable for
a period of not less than one (1) year from the date of termination.

      Previously,  Mr.  Konatich  was  employed  by  SIGA  under  an  employment
agreement  dated April 1, 1998,  as amended on January 19, 2000,  as amended and
restated on October 6, 2000, as amended on each of January 31, 2002, November 5,
2002, July 29, 2004 and February 1, 2006. Mr.  Konatich  received an annual base
salary of $230,000 and received a one-time  payment of $50,000 for prior service
as Acting Chief Executive  Officer (which duties concluded on July 2, 2004). Mr.
Konatich  served  as the  Company's  Chief  Executive  Officer  from May 1, 2006
through February 28, 2007. His employment  agreement  provided for an additional
bonus  payment at the  discretion  of the Board of  Directors  and not to exceed
twenty five percent (25%) of his annual base salary amount.  He received options
to  purchase  95,000  shares of common  stock,  at $4.44 on April 1,  1998.  The
options  vested on a pro rata  basis on the  first,  second,  third  and  fourth
anniversaries  of the agreement.  On January 19, 2000, he received an additional
grant to purchase 100,000 shares at an exercise price of $2.00 per share.  These
options  vested on a pro rata basis each quarter  through  January 19, 2002.  On
January 31, 2002, Mr. Konatich was granted an Incentive Stock Option to purchase
50,000 shares at an exercise  price of $3.94 per share.  Such options  vested in
eight equal quarterly  installments  beginning on April 20, 2002. On November 5,
2002,  Mr.  Konatich was granted an Incentive  Stock Option to purchase  150,000
shares at an exercise  price of $2.50 per share.  75,000 of these options vested
immediately  and 75,000  options  vested on September 1, 2003. On July 29, 2004,
Mr. Konatich was granted an Incentive Stock Option to purchase 150,000 shares at
an  exercise  price  of  $1.40  per  share.   75,000  of  these  options  vested
immediately,  with the remaining 75,000 options vesting on a pro rata basis from
January 1, 2005 through  December 31, 2005,  with no provision for  acceleration
under any  circumstances.  Mr. Konatich was also eligible to receive  additional
stock options and bonuses at the discretion of the Board of Directors.  SIGA was
permitted to terminate the  employment  agreement with or without cause (as such
term  was  defined  in  his  employment  agreement),   provided  that  upon  any
termination without cause, SIGA would have been obligated to continue to pay Mr.
Konatich's  salary and all other amounts due under the employment  agreement for
the remainder of the term.  If Mr.  Konatich had  terminated  due to a change of
control (as such term was defined in his employment agreement),  SIGA would have
been required to pay Mr.  Konatich a change in control  amount (as such term was
defined in his  employment  agreement)  plus his accrued and unpaid base salary,
and, upon the first event  constituting  a change of control,  all stock options
and  other  stock-based  grants  to Mr.  Konatich  would  have  immediately  and
irrevocably vested and become exercisable upon the date of such event.

      Further detail on our severance obligations to Mr. Konatich, including the
definitions  in his current  employment  agreement of "cause," "good reason" and
"change in control" is set forth  below  under the heading  "Potential  Payments
Upon Termination or Change-in-Control."

Dr. Dennis E. Hruby - Chief Scientific Officer

      On January 22, 2007,  we entered  into an amended and restated  employment
agreement with Dr. Dennis E. Hruby, our Chief Scientific  Officer which replaced
his prior  employment  agreement  (which agreement is described in the following
paragraph).  The  current  employment  agreement  expires on January  22,  2010.
Pursuant to the  employment  agreement,  we agree to pay to Dr.  Hruby an annual
base salary of  $250,000,  subject to any cost of living  adjustments  as may be
approved  by our Board,  and an annual  cash  bonus of no less than  twenty-five
percent (25%) and no more than fifty  percent (50%) of Dr.  Hruby's base salary.
Dr. Hruby is also eligible to receive such additional  bonus payments (in either


                                       22


cash or stock  options) as may be approved by our Board in its sole  discretion.
We may terminate his employment agreement (with or without cause), provided that
upon  any  termination  by us  without  cause  (including,  without  limitation,
termination without cause upon a change in control), or termination by Dr. Hruby
for good reason, we will be obligated to continue to pay Dr. Hruby's base salary
for two years, and all stock options and other  stock-based  grants to Dr. Hruby
shall  immediately and irrevocably vest and become  exercisable upon the date of
termination  and shall remain  exercisable for a period of not less than two (2)
years from the date of termination.

      Previously,  we employed Dr.  Hruby under an  employment  agreement  dated
January 1, 1998, as amended on each of June 16, 2000,  January 31, 2002, October
3, 2002 and July 29,  2004.  This  employment  agreement  would have  expired on
December 31, 2007, had the new employment  agreement  (discussed above) not been
entered  into.  Dr. Hruby  received a base salary of $225,000 per year,  and his
employment  agreement  also  provided  for  additional  bonus  payments  at  the
discretion  of the Board of Directors  and not to exceed fifty  percent (50%) of
his base salary amount.  Dr. Hruby received options to purchase 10,000 shares of
common stock at an exercise price of $5.00 per share on April 1, 1997 and 40,000
shares of common stock at an exercise price of $4.63 per share on April 1, 1998.
The options became exercisable on a pro rata basis on the first,  second,  third
and fourth  anniversaries of the employment  agreement.  Under the June 16, 2000
amendment,  Dr. Hruby was granted  options to purchase  125,000 shares of SIGA's
common stock at $2.00 per share.  The options  vested ratably over the remaining
term of the amendment.  The January 31, 2002 amendment  changed the terms of the
lock-up  agreed to in the June 16, 2000  amendment to the  employment  agreement
limiting  Hruby's ability to sell SIGA stock. On January 31, 2002, Dr. Hruby was
granted an Incentive Stock Option to purchase 50,000 shares at an exercise price
of $3.94 per  share.  Such  options  vested in four  equal  annual  installments
beginning  on August 15,  2002.  As part of the October 3, 2002  amendment,  Dr.
Hruby was granted an option to purchase 300,000 shares of common stock.  Options
with respect to 75,000  shares  vested upon the signing of the  amendment and an
additional  75,000 vested on a pro rata basis on September 1 of each 2003,  2004
and 2005.  The options  have an  exercise  price of $2.50 per share.  Dr.  Hruby
surrendered  his option to purchase up to 50,000  shares of common stock of SIGA
at an exercise price of $3.94 that he was granted under an earlier amendment. On
July 29,  2004,  Dr.  Hruby was granted an  Incentive  Stock  Option to purchase
150,000 shares at an exercise price of $1.40 per share,  which options vested in
75,000 share  increments  on December 31 of each year,  commencing  December 31,
2005. Dr. Hruby was eligible to receive  additional stock options and bonuses at
the  discretion of the Board of  Directors.  SIGA was permitted to terminate the
employment  agreement  with or  without  cause (as such term is  defined  in the
employment  agreement),  provided that upon any  termination  without cause SIGA
would  have  been  obligated  to  continue  to pay Dr.  Hruby's  salary  for the
remainder of the term. In addition,  SIGA had the right to terminate Dr. Hruby's
employment upon one (1) year written notice with such termination  being treated
as a  termination  for cause.  If Dr.  Hruby was  terminated  due to a change of
control (as such term was defined in his employment agreement),  SIGA would have
been  required  to pay Dr.  Hruby a change in  control  amount (as such term was
defined in his  employment  agreement)  plus his accrued and unpaid base salary,
and, upon the first event  constituting  a change of control,  all stock options
and other stock-based grants to Dr. Hruby would have immediately and irrevocably
vested and become exercisable upon the date of such event.

      Further  detail on our severance  obligations  to Dr. Hruby  including the
definitions  in his current  employment  agreement of "cause," "good reason" and
"change in control" is set forth  below  under the heading  "Potential  Payments
Upon Termination or Change-in-Control."

Dr. Bernard L. Kasten - Former Chief Executive Officer

      We employed Dr.  Bernard L. Kasten,  as SIGA's  Chief  Executive  Officer,
under an employment  agreement dated July 2, 2004. Dr. Kasten received an annual
base  salary  of  $250,000  and  his  employment  agreement  also  provided  for
additional  bonus payments at the discretion of the Board of Directors.  On July
2, 2004, he received  options to purchase  2,500,000 shares of common stock with
an exercise price of $1.30 per share, of which 500,000 shares vested on the date
of grant;  with respect to the next  1,000,000  shares,  an  additional  166,666
shares  vested on the end of each six (6) month period after date of grant until
the end of the sixth six (6) month period at which time  166,667  shares were to
vest. Effective April 30, 2006, SIGA and Dr. Kasten reached an agreement for Dr.
Kasten's resignation. In connection with such agreed upon resignation,  SIGA and
Dr.  Kasten  entered  into a  Separation  Agreement  dated  March 31,  2006 (the
"Separation  Agreement").  Under the provisions of the Separation Agreement, Dr.
Kasten  received his salary on the existing terms and conditions as set forth in
his employment  agreement with SIGA, dated July 2, 2004 (the "Kasten  Employment
Agreement")  in lieu of any other  severance or payment,  through  September 16,
2006  (the  "Separation  Period").   Concurrently  with  the  execution  of  the
Separation  Agreement,  SIGA and Dr. Kasten also amended Dr. Kasten's  Incentive
Stock Option Agreement such that Dr. Kasten's  "Milestone Options" (as such term
is defined in the Kasten  Employment  Agreement) were cancelled and Dr. Kasten's
"Time  Vested  Options"  (as  such  term is  defined  in the  Kasten  Employment
Agreement)  were amended such that with respect to the Time Vested Options which
had not vested as of the date of the  Separation  Agreement,  such  options will
vest as  follows:  with  respect to  166,666  shares as of July 2, 2006 and with
respect to the  remaining  83,334  shares,  as of January 2, 2007.  Time  Vested
Options  granted to Dr. Kasten which vested prior to the date


                                       23


of the  Separation  Agreement  shall  remain  unchanged.  Dr.  Kasten  was  also
permitted to continue to receive medical and/or dental insurance  benefits under
the relevant  SIGA plans until (i) the end of the Remaining  Tenure  (defined as
the earlier of April 30, 2006 or Dr. Kasten's obtaining new employment), (ii) he
becomes  entitled to Medicare or (iii) he becomes  eligible for  coverage  under
medical and/or dental  insurance  benefit plans,  as the case may be, of another
employer through his future  employment,  whichever occurs first. The Separation
Agreement also contains  mutual  non-disparagement  and release terms,  requires
that Dr. Kasten remain  available to SIGA on a reasonable basis for transitional
purposes during the Separation  Period and requires SIGA to indemnify Dr. Kasten
under the terms of its certificate of incorporation and bylaws for acts relating
to his employment.

Outstanding Equity Awards at Fiscal Year End

      The  following  table  provides  certain  summary  information  concerning
unexercised  options and equity  incentive plan awards for each Named  Executive
Officer as of December 31, 2006.



                                                             Option Awards

                                                                   Equity
                                                                 Incentive
                                                                    Plan
                                 Number of       Number of        Awards:
                                Securities      Securities       Number of
                                Underlying      Underlying       Securities
                                Unexercised     Unexercised      Underlying
                                  Options         Options       Unexercised       Option           Option
                                    (#)             (#)           Unearned       Exercise       Expiration
 Name and Principal Position    Exercisable    Unexercisable   Options (#)      Price ($)          Date

                                                                                
Bernard L. Kasten, M.D.            100,000           --             --             1.81          3/20/2007
Chief Executive Officer (1)      1,250,000           --             --             1.30           7/2/2014

Thomas N. Konatich                  95,000           --             --             4.44           4/1/2008
Chief Financial Officer (2)        100,000           --             --             2.00          1/19/2010
                                    50,000           --             --             3.94          1/31/2012
                                   150,000           --             --             2.50         11/15/2012
                                   150,000           --             --             1.40          7/29/2014

Dennis E. Hruby, Ph.D.              10,000           --             --             5.00           4/1/2007
Chief Scientific Officer            40,000           --             --             4.63           4/1/2008
                                   125,000           --             --             2.00          5/25/2010
                                   300,000           --             --             2.50          7/23/2012
                                   150,000           --             --             1.40          6/29/2014

Eric A. Rose, M.D.                 600,000           --             --             2.50           5/3/2001
Chief Executive Officer (3)         10,000           --             --             1.22           6/2/2005
                                    10,000           --             --             2.72         12/19/2006



                                       24





                                                         Stock Awards

                                                                                     Equity
                                                                   Equity           Incentive
                                                                  Incentive       Plan Awards:
                                                                Plan Awards:        Market or
                                 Number of       Market           Number of          Payout
                                 Shares or      Value of          Unearned          Value of
                                  Units of      Shares or       Shares, Units       Unearned
                                    Stock        Units of         or Other        Shares, Units
                                    That        Stock That       Rights That        or Other
                                  Have Not       Have Not         Have Not        Rights That
 Name and Principal Position       Vested       Vested (#)       Vested (#)         have Not
                                                                                   vested ($)
                                                                         
Bernard L. Kasten, M.D.              --             --              --               --
Chief Executive Officer (1)          --             --              --               --

Thomas N. Konatich                   --             --              --               --
Chief Financial Officer (2)          --             --              --               --
                                     --             --              --               --
                                     --             --              --               --
                                     --             --              --               --

Dennis E. Hruby, Ph.D.               --             --              --               --
Chief Scientific Officer             --             --              --               --
                                     --             --              --               --
                                     --             --              --               --
                                     --             --              --               --

Eric A. Rose, M.D.                   --             --              --               --
Chief Executive Officer (3)          --             --              --               --
                                     --             --              --               --


(1)   Dr.  Kasten  became Chief  Executive  Officer on July 2, 2004.  His annual
      salary was $250,000.  Dr. Kasten  resigned as Chief  Executive  Officer of
      SIGA effective as of April 30, 2006.

(2)   Mr.  Konatich was appointed to serve in an  additional  capacity as Acting
      Chief Executive  Officer  effective from May 1, 2006 through  February 28,
      2007.

(3)   Dr. Rose became Chief Executive Officer on March 1, 2007.

Option Exercises and Stock Vested

      During the fiscal year ended  December 31, 2006 no options were  exercised
by any of our officers. Our officers did not receive any stock awards during the
current year or any other year.

Fiscal Year-End Option Values

      The following table provides certain summary information  concerning stock
options held as of December 31, 2006 by SIGA's Named Executive Officers.



                                  Number of Securities              Value of Unexercised
                                Underlying Unexercised            In-The-Money Options At
                                       Options #                  Fiscal Year-End ($) (1)
                              Exercisable    Unexercisable      Exercisable    Unexercisable
                                                                           
Bernard L. Kasten, M.D         1,350,000            --           $3,256,500            --
Thomas N. Konatich               545,000            --           $  715,000            --
Dennis E. Hruby, Ph.D.           625,000            --           $  946,250            --
Eric A. Rose, M.D                620,000            --           $  785,600            --


(1)   Based upon the closing  price on  December  31,  2006,  as reported on the
      Nasdaq SmallCap Market and the exercise price per option.

Potential Payments Upon Termination or Change in Control

Severance Arrangement for Thomas N. Konatich

      The  following  table and  footnotes  describe and quantify the  potential
payments upon termination or change in control for Mr.  Konatich,  assuming that
termination or change-in-control was effective as of December 31, 2006:



                                           Termination by the
                                            Company without
                                            cause (or by the     Termination upon    Termination by the
                                            officer for good        death or          Company due to a
     Thomas N. Konatich                          cause)            disability        change in control
                                                                                
Aggregate monthly cash payments              $   249,167           $        --           $        --
Lump sum cash payment                                 --                    --               249,167
Value of accelerated stock options                    --                    --                    --
                                             -----------           -----------           -----------
     Total                                   $   249,167           $        --           $   249,167
                                             ===========           ===========           ===========


      Pursuant to Mr. Konatich's prior employment agreement (which was in effect
as  of  December  31,   2006),   the   following   termination   and  change  in
control-related  circumstances  would trigger payments or the provision of other
benefits:

            o     Termination by the Company for cause.

            o     Termination  by the Company based on Mr.  Konatich's  death or
                  disability.

            o     Termination by the Company  without cause (or by Mr.  Konatich
                  for good reason).

            o     Termination by the Company due to a change in control.

Payments Upon any Termination other than in connection with a Change in Control:

      If Mr. Konatich was terminated for cause or disability,  or if he resigned
for reasons other than a material breach by the Company of its obligations under
his employment agreement,  or a material reduction of his duties, or if he died,
then the Company had no obligation to pay Mr.  Konatich any amount,  whether for
salary,  benefits,  bonuses, or other compensation or expense  reimbursements of
any kind,  accruing after his  termination,  and such rights would be, except as


                                       25


otherwise  required by law,  forfeited  immediately upon  termination.  However,
payments of base salary would  continue  until the  expiration of the employment
agreement  where Mr.  Konatich was terminated  for death or  disability.  If the
Company had terminated Mr. Konatich  without cause,  then the Company would have
been  obligated to continue to pay Mr.  Konatich's  salary and all other amounts
due  under  the  employment  agreement  for  the  remainder  of the  term of the
employment agreement (as if no early termination had occurred).

Payments Upon any Termination in connection with a Change in Control:

Applicability.  The  change in  control  provisions  applied  if Mr.  Konatich's
employment was terminated (or a notice of termination is given) 90 days prior to
or within  18  months  after a change in  control.  Pursuant  to the  employment
agreement,  a change in control would have occurred (i) upon an  acquisition  of
35% of the voting power of economic interest of the Company's common stock, (ii)
certain changes in the majority of the board of director's membership, (iii) the
approval by the Company's  stockholders of certain  reorganizations,  mergers or
consolidations,  (iv)  the  sale or other  disposition  of more  than 50% of the
Company's  assets,  (iv) a  fundamental  change in the business or (v) a hostile
takeover.

Change of Control Payment.  If Mr. Konatich was terminated within the applicable
period other than for death,  disability,  or by him without cause,  the Company
would have been  required  to pay to him,  in a lump sum, on or prior to the 5th
day  following  the date of  termination,  an amount equal to his salary and all
other amounts due under his employment  agreement for the remainder of its term,
plus a gross up payment and any accrued and unpaid base salary.

Stock  Option  Floor.  Upon a change  in  control  all stock  options  and other
stock-based  grants to Mr.  Konatich by SIGA would have  immediately  vested and
become exercisable as of such date.

Gross Up Payment. If Mr. Konatich had incurred the excise tax imposed by the IRS
on "Excess  Parachute  Payments"  the Company would have been required to pay an
additional  amount such that the amount retained by Mr. Konatich after deduction
of any excise tax on both the Excess  Parachute  Payment and any federal,  state
and local  income tax  (together  with  penalties  and  interest) as well as the
excise tax due on the gross up itself  would  have been equal to the  amounts he
would have received upon a change of control had no such tax been imposed.

Satisfactory  Alternative.  Mr.  Konatich's  rights with  respect to a change in
control termination would not have applied if, prior to or simultaneously with a
such a termination due to a change in control,  he was offered employment within
the New York Metro area by another business as its chief financial  officer at a
level of compensation equal to or greater than his compensation by the Company.

      Pursuant  to  Mr.  Konatich's  current  employment  agreement  (which  was
effective  as of January 22,  2007),  the  following  termination  and change in
control-related  circumstances  would trigger payments or the provision of other
benefits:

            o     Termination  by the Company  without cause or by Mr.  Konatich
                  for good reason.

            o     Termination by the Company within 90 days of the occurrence of
                  a change in control (other than for cause)

            o     Termination  by the  Company  for  cause  or by  Mr.  Konatich
                  without good reason.

            o     Termination  by the Company based on Mr.  Konatich's  death or
                  total disability.

      If Mr. Konatich's  employment  agreement is terminated without cause or if
Mr. Konatich  terminates his employment for good reason,  he will be entitled to
the following:  (i) any accrued but unpaid salary for services  rendered through
the date of termination (ii) any vacation accrued to the date of termination, in
accordance  with Company policy;  (iii) any accrued but unpaid expenses  through
the  date of  termination  required  to be  reimbursed  in  accordance  with his
employment  agreement;  (iv)  any  benefits  to which  he may be  entitled  upon
termination  pursuant  to the  plans,  programs  and grants  referred  to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants,  (v) the continued payment of his salary for two (2) years; and (vi) the
Company  shall take all such action as is necessary  such that all stock options
and other stock-based grants to Mr. Konatich shall,  immediately and irrevocably
vest and  become  exercisable  as of the date of  termination  and shall  remain
exercisable  for a  period  of not  less  than  one (1)  year  from  the date of
termination.

      If Mr. Konatich's  employment agreement is terminated within 90 days after
the occurrence of a change in control other than for cause,  he will be entitled
to the  following:  (i) any  accrued  but unpaid  salary for  services  rendered
through  the  date of  termination  (ii)  any  vacation  accrued  to the date of
termination,  in accordance  with Company  policy;  (iii) any accrued but unpaid
expenses through the date of termination required to be reimbursed in accordance
with his  employment


                                       26


agreement;  (iv)  any  benefits  to which he may be  entitled  upon  termination
pursuant  to the  plans,  programs  and  grants  referred  to in the  employment
agreement in accordance with the terms of such plans,  programs and grants,  (v)
the  continued  payment of his salary  for two (2) years;  and (vi) the  Company
shall take all such action as is necessary such that all stock options and other
stock-based  grants to Mr. Konatich shall,  immediately and irrevocably vest and
become  exercisable as of the date of termination  and shall remain  exercisable
for a period of not less than one (1) year from the date of termination.

      If Mr. Konatich's employment is terminated for cause, or if he voluntarily
terminates his employment, he will be entitled to the following: (i) any accrued
but unpaid salary for services rendered through the date of termination (ii) any
vacation accrued to the date of termination,  in accordance with Company policy;
(iii) any accrued but unpaid expenses  through the date of termination  required
to be reimbursed  in  accordance  with his  employment  agreement;  and (iv) any
benefits to which he may be  entitled  upon  termination  pursuant to the plans,
programs and grants  referred to in the employment  agreement in accordance with
the terms of such plans, programs and grants.

      If Mr. Konatich's  employment is terminated prior to the expiration of the
term by reason of death or total disability, his estate or beneficiaries will be
entitled  to the  following:  (i) any  accrued  but unpaid  salary for  services
rendered  through the date of termination  (ii) any vacation accrued to the date
of termination,  in accordance with Company policy; (iii) any accrued but unpaid
expenses through the date of termination required to be reimbursed in accordance
with his employment agreement; and (iv) any benefits to which he may be entitled
upon termination  pursuant to the plans,  programs and grants referred to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants.

Severance Arrangement for Dr. Hruby

      The  following  table and  footnotes  describe and quantify the  potential
payments  upon  termination  or change in control for Dr.  Hruby,  assuming that
termination or change-in-control was effective as of December 31, 2006:



                                      Termination by the
                                       Company without
                                       cause (or by the    Termination upon      Termination by the
                                       officer for good        death or            Company due to a
     Dr. Dennis E. Hruby                    cause)            disability          change in control
                                                                            
Aggregate monthly cash payments         $    225,000         $         --            $         --
Lump sum cash payment                             --                   --                 225,000
Value of accelerated stock options                --                   --                      --
                                        ------------         ------------            ------------
     Total                              $    225,000         $         --            $    225,000
                                        ============         ============            ============


      Pursuant to Dr. Hruby's prior employment agreement (which was in effect as
of December 31, 2006), the following  termination and change in  control-related
circumstances would trigger payments or the provision of other benefits:

            o     Termination  by the Company for cause  (including by providing
                  one (1)  year  written  notice  with  such  termination  being
                  treated as a termination for cause).

            o     Termination  by the  Company  based  on Dr.  Hruby's  death or
                  disability.

            o     Termination by the Company  without cause (or by Dr. Hruby for
                  good reason).

            o     Termination by the Company due to a change in control.

Payments Upon any Termination other than in connection with a Change in Control:

      If Dr. Hruby was terminated for cause or disability, or if he resigned for
reasons other than a material breach by the Company of its obligations under his
employment agreement, or a material reduction of his duties, or if he died, then
the Company had no obligation  to pay Dr. Hruby any amount,  whether for salary,
benefits,  bonuses, or other compensation or expense reimbursements of any kind,
accruing  after his  termination,  and such rights would be, except as otherwise
required by law, forfeited  immediately upon termination.  However,  payments of
base salary would  continue  until the  expiration of the  employment  agreement
where Dr.  Hruby was  terminated  for death or  disability.  If the  Company had
terminated Dr. Hruby without  cause,  then the Company would have been obligated
to  continue  to pay Dr.  Hruby's  salary  and all other  amounts  due under the
employment  agreement for the remainder of the term of the employment  agreement
(as if no early termination had occurred).


                                       27


Payments Upon any Termination in connection with a Change in Control:

Applicability.   The  change  in  control  provisions  applied  if  Dr.  Hruby's
employment was terminated (or a notice of termination is given) 90 days prior to
or within  12  months  after a change in  control.  Pursuant  to the  employment
agreement,  a change in control would have occurred (i) upon an  acquisition  of
35% of the voting power of economic interest of the Company's common stock, (ii)
certain changes in the majority of the board of director's membership, (iii) the
approval by the Company's  stockholders of certain  reorganizations,  mergers or
consolidations,  (iv)  the  sale or other  disposition  of more  than 50% of the
Company's  assets,  (iv) a  fundamental  change in the business or (v) a hostile
takeover.

Change of Control  Payment.  If Dr. Hruby was  terminated  within the applicable
period other than for death,  disability,  or by him for any reason, the Company
would have been  required  to pay to him,  in a lump sum, on or prior to the 5th
day  following  the date of  termination,  an amount equal to his salary and all
other amounts due under his employment  agreement for the remainder of its term,
plus a gross up payment and any accrued and unpaid base salary.

Stock  Option  Floor.  Upon a change  in  control  all stock  options  and other
stock-based grants to Dr. Hruby by SIGA would have immediately vested and become
exercisable as of such date.

Gross Up Payment. If Dr. Hruby had incurred the excise tax imposed by the IRS on
"Excess  Parachute  Payments"  the  Company  would have been  required to pay an
additional  amount such that the amount retained by Dr. Hruby after deduction of
any excise tax on both the Excess Parachute  Payment and any federal,  state and
local income tax  (together  with  penalties and interest) as well as the excise
tax due on the gross up itself  would  have been  equal to the  amounts he would
have received upon a change of control had no such tax been imposed.

Satisfactory Alternative. Dr. Hruby's rights with respect to a change in control
termination  would not have applied if, prior to or  simultaneously  with such a
termination  due to a change in  control,  he was offered  employment  within 50
miles of Albany Oregon by another  business at a level of compensation  equal to
or greater than his compensation by SIGA

      Pursuant to Dr. Hruby's current employment  agreement (which was effective
as of January 22, 2007), the following termination and change in control-related
circumstances would trigger payments or the provision of other benefits:

            o     Termination  by the Company  without cause or by Dr. Hruby for
                  good reason.

            o     Termination by the Company within 90 days of the occurrence of
                  a change in control (other than for cause)

            o     Termination  by the Company for cause or by Dr. Hruby  without
                  good reason.

            o     Termination by the Company based on Dr. Hruby's death or total
                  disability.

      If Dr. Hruby's employment  agreement is terminated without cause or if Dr.
Hruby  terminates  his  employment  for good reason,  he will be entitled to the
following:  (i) any accrued but unpaid salary for services  rendered through the
date of termination  (ii) any vacation  accrued to the date of  termination,  in
accordance  with Company policy;  (iii) any accrued but unpaid expenses  through
the  date of  termination  required  to be  reimbursed  in  accordance  with his
employment  agreement;  (iv)  any  benefits  to which  he may be  entitled  upon
termination  pursuant  to the  plans,  programs  and grants  referred  to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants,  (v) the continued payment of his salary for two (2) years; and (vi) the
Company  shall take all such action as is necessary  such that all stock options
and other  stock-based  grants to Dr. Hruby shall,  immediately  and irrevocably
vest and  become  exercisable  as of the date of  termination  and shall  remain
exercisable  for a  period  of not  less  than  two (2)  years  from the date of
termination.

      If Dr. Hruby's employment agreement is terminated within 90 days after the
occurrence of a change in control  other than for cause,  he will be entitled to
the following:  (i) any accrued but unpaid salary for services  rendered through
the date of termination (ii) any vacation accrued to the date of termination, in
accordance  with Company policy;  (iii) any accrued but unpaid expenses  through
the  date of  termination  required  to be  reimbursed  in  accordance  with his
employment  agreement;  (iv)  any  benefits  to which  he may be  entitled  upon
termination  pursuant  to the  plans,  programs  and grants  referred  to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants,  (v) the continued payment of his salary for two (2) years; and (vi) the
Company  shall take all such action as is necessary  such that all stock options
and other  stock-based  grants to Dr. Hruby shall,  immediately  and irrevocably
vest and  become  exercisable  as of the date of  termination  and shall  remain
exercisable  for a  period  of not  less  than  two (2)  years  from the date of
termination.

      If Dr. Hruby's  employment is terminated  for cause,  or if he voluntarily
terminates his employment, he will be entitled to the following: (i) any accrued
but unpaid salary for services rendered through the date of termination (ii) any


                                       28


vacation accrued to the date of termination,  in accordance with Company policy;
(iii) any accrued but unpaid expenses  through the date of termination  required
to be reimbursed  in  accordance  with his  employment  agreement;  and (iv) any
benefits to which he may be  entitled  upon  termination  pursuant to the plans,
programs and grants  referred to in the employment  agreement in accordance with
the terms of such plans, programs and grants.

      If Dr.  Hruby's  employment is terminated  prior to the  expiration of the
term by reason of death or total disability, his estate or beneficiaries will be
entitled  to the  following:  (i) any  accrued  but unpaid  salary for  services
rendered  through the date of termination  (ii) any vacation accrued to the date
of termination,  in accordance with Company policy; (iii) any accrued but unpaid
expenses through the date of termination required to be reimbursed in accordance
with his employment agreement; and (iv) any benefits to which he may be entitled
upon termination  pursuant to the plans,  programs and grants referred to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants.

Severance Arrangement for Dr. Bernard Kasten

      Dr. Bernard L. Kasten served as SIGA's Chief  Executive  Officer from July
2, 2004 to April 30, 2006,  under an  employment  agreement  dated July 2, 2004.
Effective  April 30, 2006,  SIGA and Dr.  Kasten  reached an  agreement  for Dr.
Kasten's resignation. In connection with such agreed upon resignation,  SIGA and
Dr.  Kasten  entered  into a  Separation  Agreement  dated  March 31,  2006 (the
"Separation  Agreement").  Under the provisions of the Separation Agreement, Dr.
Kasten  received his salary on the existing terms and conditions as set forth in
his employment  agreement with SIGA, dated July 2, 2004 (the "Kasten  Employment
Agreement")  in lieu of any other  severance or payment,  through  September 16,
2006  (the  "Separation  Period").   Concurrently  with  the  execution  of  the
Separation  Agreement,  SIGA and Dr. Kasten also amended Dr. Kasten's  Incentive
Stock Option Agreement such that Dr. Kasten's  "Milestone Options" (as such term
is defined in the Kasten  Employment  Agreement) were cancelled and Dr. Kasten's
"Time  Vested  Options"  (as  such  term is  defined  in the  Kasten  Employment
Agreement)  were amended such that with respect to the Time Vested Options which
had not vested as of the date of the Separation  Agreement,  such options vested
as follows: with respect to 166,666 shares, as of July 2, 2006, and with respect
to the  remaining  83,334  shares,  as of January 2, 2007.  Time Vested  Options
granted to Dr. Kasten which vested prior to the date of the Separation Agreement
shall remain unchanged.  Dr. Kasten was permitted to continue to receive medical
and/or dental insurance benefits under the relevant SIGA plans until (i) the end
of the  Remaining  Tenure  (defined  as the  earlier  of April  30,  2006 or Dr.
Kasten's obtaining new employment), (ii) he became entitled to Medicare or (iii)
he became  eligible for coverage under medical and/or dental  insurance  benefit
plans, as the case may be, of another  employer  through his future  employment,
whichever  occurred  first.  The  Separation   Agreement  also  contains  mutual
non-disparagement  and release terms,  requires that Dr. Kasten remain available
to SIGA on a reasonable  basis for  transitional  purposes during the Separation
Period  and  requires  SIGA to  indemnify  Dr.  Kasten  under  the  terms of its
certificate of incorporation and bylaws for acts relating to his employment.

Severance Arrangement for Dr. Rose

      Pursuant to Dr. Rose's current  employment  agreement (which was effective
as of January 22, 2007), the following termination and change in control-related
circumstances would trigger payments or the provision of other benefits:

            o     Termination  by the Company  without  cause or by Dr. Rose for
                  good reason.

            o     Termination by the Company within 90 days of the occurrence of
                  a change in control (other than for cause)

            o     Termination  by the Company  for cause or by Dr. Rose  without
                  good reason.

            o     Termination  by the Company based on Dr. Rose's death or total
                  disability.

      If Dr. Rose's employment  agreement is terminated  without cause or if Dr.
Rose  terminates  his  employment  for good  reason,  he will be entitled to the
following:  (i) any accrued but unpaid salary for services  rendered through the
date of termination  (ii) any vacation  accrued to the date of  termination,  in
accordance  with Company policy;  (iii) any accrued but unpaid expenses  through
the  date of  termination  required  to be  reimbursed  in  accordance  with his
employment  agreement;  (iv)  any  benefits  to which  he may be  entitled  upon
termination  pursuant  to the  plans,  programs  and grants  referred  to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants,  (v) the continued  payment of his salary for one (1) year; and (vi) the
Company  shall take all such action as is necessary  such that all stock options
and other stock-based grants to Dr. Rose shall, immediately and irrevocably vest
and  become  exercisable  as  of  the  date  of  termination  and  shall  remain
exercisable  for a  period  of not  less  than  one (1)  year  from  the date of
termination.

      If Dr. Rose's employment  agreement is terminated within 90 days after the
occurrence of a change in control  other than for cause,  he will be entitled to
the following:  (i) any accrued but unpaid salary for services  rendered through
the date


                                       29


of  termination  (ii)  any  vacation  accrued  to the  date of  termination,  in
accordance  with Company policy;  (iii) any accrued but unpaid expenses  through
the  date of  termination  required  to be  reimbursed  in  accordance  with his
employment  agreement;  (iv)  any  benefits  to which  he may be  entitled  upon
termination  pursuant  to the  plans,  programs  and grants  referred  to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants,  (v) the continued  payment of his salary for one (1) year; and (vi) the
Company  shall take all such action as is necessary  such that all stock options
and other stock-based grants to Dr. Rose shall, immediately and irrevocably vest
and  become  exercisable  as  of  the  date  of  termination  and  shall  remain
exercisable  for a  period  of not  less  than  one (1)  year  from  the date of
termination.

      If Dr. Rose's  employment is terminated  for cause,  or if he  voluntarily
terminates his employment, he will be entitled to the following: (i) any accrued
but unpaid salary for services rendered through the date of termination (ii) any
vacation accrued to the date of termination,  in accordance with Company policy;
(iii) any accrued but unpaid expenses  through the date of termination  required
to be reimbursed  in  accordance  with his  employment  agreement;  and (iv) any
benefits to which he may be  entitled  upon  termination  pursuant to the plans,
programs and grants  referred to in the employment  agreement in accordance with
the terms of such plans, programs and grants.

      If Dr. Rose's employment is terminated prior to the expiration of the term
by reason of death or total  disability,  his  estate or  beneficiaries  will be
entitled  to the  following:  (i) any  accrued  but unpaid  salary for  services
rendered  through the date of termination  (ii) any vacation accrued to the date
of termination,  in accordance with Company policy; (iii) any accrued but unpaid
expenses through the date of termination required to be reimbursed in accordance
with his employment agreement; and (iv) any benefits to which he may be entitled
upon termination  pursuant to the plans,  programs and grants referred to in the
employment  agreement in accordance  with the terms of such plans,  programs and
grants.

Other General Terms

Circumstances Triggering Payments

      "Cause,"  "good  reason" and "change of control"  are defined in Dr. Rose,
Mr. Konatich and Dr. Hruby's current employment agreement as follows:

"Cause" generally includes:

      o     executive  officer's  neglect or  failure or refusal to perform  his
            duties under the applicable  employment  agreement  (other than as a
            result of total or  partial  incapacity  due to  physical  or mental
            illness);

      o     any act by or  omission  of  executive  officer  constituting  gross
            negligence or willful  misconduct in connection with the performance
            of his duties that could reasonably be expected to materially injure
            the reputation, business or business relationships of the Company or
            any of its affiliates;

      o     perpetration   of  an  intentional  and  knowing  fraud  against  or
            affecting  the  Company or any of its  affiliates  or any  customer,
            client, agent, or employee thereof;

      o     the  commission  by or  indictment  of  executive  officer for (A) a
            felony or (B) any  misdemeanor  involving moral  turpitude,  deceit,
            dishonesty or fraud  ("indictment,"  for these  purposes,  meaning a
            United States-based indictment,  probable cause hearing or any other
            procedure pursuant to which an initial  determination of probable or
            reasonable cause with respect to such offense is made);

      o     the  breach of a  covenant  set forth in the  applicable  employment
            agreement; or

      o     any other material breach the applicable employment agreement.

"Good reason" generally includes:

      o     the Company failing to pay the executive officer his base salary;

      o     executive  officer  no longer  holding  his  agreed  upon  office or
            offices of equivalent  stature, or his functions and/or duties being
            materially diminished; or

      o     executive  officer's  job site being  involuntarily  relocated  to a
            location  which is more than fifty  (50) miles from the agreed  upon
            region.

a "Change in Control" is deemed to occur upon:

      o     the   consummation   of  a  transaction   or  a  series  of  related
            transactions pursuant to which any "person" (as such term is used in
            Sections 13(d) and 14(d)(2) of the  Securities  Exchange Act of 1934
            ("Exchange Act"), other than the executive officer,  his designee(s)
            or "affiliate(s)" (as defined in Rule 12b-2 under the Exchange Act),
            is or becomes the "beneficial owner" (as defined in Rule 13d-3 under
            the Exchange  Act),  directly or  indirectly,  of  securities of the
            Company  representing  forty  percent  (40%) or more of the combined
            voting power of the Company's then outstanding securities;


                                       30


      o     stockholders of the Company approve a merger or consolidation of the
            Company with any other entity,  other than a merger or consolidation
            which  would  result  in  the  voting   securities  of  the  Company
            outstanding   immediately  prior  thereto  continuing  to  represent
            (either by remaining  outstanding or by being  converted into voting
            securities of the surviving  entity) more than eighty  percent (80%)
            of the combined voting power of the voting securities of the Company
            or such surviving entity  outstanding  immediately after such merger
            or consolidation; or

      o     the   stockholders  of  the  Company  approve  a  plan  of  complete
            liquidation  of  the  Company  or  an  agreement  for  the  sale  or
            disposition  by the Company of, or the Company sells or disposes of,
            all or substantially all of the Company's assets.

Pursuant to their current employment agreements, during the term thereof plus an
additional twenty four months  thereafter,  Dr. Rose, Mr. Konatich and Dr. Hruby
have agreed not to engage in any  competitive  business with us or to induce our
employees to terminate their employment or to solicit our customers. We agree to
indemnify  each  of  them  under  their  respective   employment  agreement  for
liabilities  incurred  because of their  employment  and to provide each of them
with the full  protection of any  directors' and officers'  liability  insurance
policies maintained generally for the benefit of our officers.

Under their prior  employment  agreement,  Mr.  Konatich  and Dr. Hruby also had
confidentiality and non-competition obligations to the Company.

Equity Compensation Plan Information

      The following table sets forth certain  compensation plan information with
respect to both equity  compensation  plans  approved  by  security  holders and
equity  compensation  plans not approved by security  holders as of December 31,
2006:



                                      Number of                                  Number of securities
                                   securities to be       Weighted-average        remaining available
                                     issued upon           exercise price         for future issuance
                                     exercise of           of outstanding            under equity
                                     outstanding              options,            compensation plans
                                  options, warrants         warrants and         (excluding securities
Plan Category                         and rights               rights            reflected in column (a))
                                         (a)                     (b)                      (c)
                                                                             
Equity compensation plans
approved by security holders (1)        7,546,145                $2.07                2,341,399

Equity compensation plans not
approved by security holders              190,000                $2.00                       --

Total                                   7,736,145                $2.07                2,341,399


(1)   SIGA   Technologies,   Inc.,  Amended  and  Restated  1996  Incentive  and
      Non-Qualified Stock Option Plan.

      On December 31, 2006,  options  awarded  outside of the  Company's  equity
compensation  plan included  125,000  options  awarded to an employee and 65,000
options  awarded to  consultants.  In May 2000,  the  Company  awarded its Chief
Scientific  Officer  options to acquire  125,000 shares of the Company's  common
stock at an exercise price of $2.00 per share. In July 2000, the Company entered
into an agreement with a consultant to serve as the Company's  public  relations
agent and  awarded the  consultant  options to acquire  shares of the  Company's
common  stock.  On December 31, 2006,  the  consultant  held 27,500  options and
37,500  options  with an exercise  price of $1.50 per share and $1.75 per share,
respectively.

Director Compensation

      During the fiscal year ending  December 31, 2006, the named  Directors and
Officers of SIGA received  long-term  incentive  compensation  under the Plan as
shown in the following table.



                                                                         Non-Equity
                                                                          Incentive      Nonqualified
                              Fees Earned       Stock      Option           Plan           Deferred       All Other
                               or paid in      Awards      Awards       Compensation     Compensation    Compensation    Total
Name                            Cash ($)         ($)         ($)             ($)         earnings ($)        ($)          ($)
                                                                                                    
James J. Antal (3) (4)           17,000           --        14,850            --              --              --         31,850
Thomas E. Constance              10,000           --        14,850            --              --              --         24,850
Donald G. Drapkin (6)             9,000           --        14,850            --              --              --         23,850
Scott M. Hammer, M.D. (2)            --           --        37,125            --              --              --         37,125
Bernard L. Kasten, M.D. (1)       5,000           --            --            --              --              --          5,000
Adnan M. Mjalli, Ph.D.            9,000           --        14,850            --              --              --         23,850
Mehmet C. Oz, M.D.                5,000           --        14,850            --              --              --         19,850
Eric A. Rose, M.D. (5)            9,000           --        14,850            --              --              --         23,850
Paul G. Savas (3) (6)            20,000           --        14,850            --              --              --         34,850
Judy S. Slotkin (3) (4)          17,500           --        14,850            --              --              --         32,350
Michael Weiner, M.D. (4) (6)     11,000           --        14,850            --              --              --         25,850


(1)   Dr. Kasten served on our Board of Directors until December 19, 2006.

(2)   Dr.  Hammer was elected to serve on our Board of Directors on December 19,
      2006.

(3)   Member of the Audit Committee

(4)   Member of the Nominating and Corporate Governance Committee

(5)   Chairman of the Board

(6)   Member of the Compensation Committee

         The aggregate number of stock option awards held by each of the
directors at December 31, 2006, and the number of stock option awards granted in
the current fiscal year are shown in the following table:

                                                            Total Option
                                    Option Awards              Awards
                                     During the             Outstanding
                                    Current Year          at December 31,
Name                                     (#)                  2006 (#)

James J. Antal                           10,000                 45,000
Thomas E. Constance                      10,000                245,000
Donald G. Drapkin                        10,000              1,145,000
Scott M. Hammer, M.D.                    25,000                 25,000
Bernard L. Kasten, M.D.                      --              1,350,000
Adnan M. Mjalli, Ph.D.                   10,000                 45,000
Mehmet C. Oz, M.D.                       10,000                120,000
Eric A. Rose, M.D.                       10,000                620,000
Paul G. Savas                            10,000                 45,000
Judy S. Slotkin                          10,000                 45,000
Michael Weiner, M.D.                     10,000                120,000

Director Fees and Equity Compensation

      Directors  who are not  currently  receiving  compensation  as officers or
employees of the Company or any of its affiliates receive $1,000 per meeting for
board  meetings  and  will  be  reimbursed  for  expenses  incurred  by  them in
connection  with  serving on our Board of  Directors.  The chairman of the Audit
Committee  will receive  $1,000 per meeting for meetings of the Audit  Committee
and all other members of the Audit  Committee  will receive $500 per meeting for


                                       31


meetings  of  the  Audit  Committee.   Members  of  Compensation  Committee  and
Nominating and Corporate  Governance Committee will receive $500 per meeting for
meetings of the Compensation  Committee and Nominating and Corporate  Governance
Committee.

      Non-employee  directors  will receive an initial grant of 25,000  options,
upon such  non-employee  director's  first  election to the Board of  Directors,
which such  options  will be granted  under  SIGA's  Amended and  Restated  1996
Incentive  and  Non-Qualified  Stock  Option  Plan.  In  addition,  non-employee
directors  will receive an annual grant of 10,000  options under SIGA's  Amended
and Restated 1996 Incentive and  Non-Qualified  Stock Option Plan,  made at each
Annual Meeting and  commencing  with the 2005 Annual  Meeting.  All such options
have an exercise  price equal to the fair market  value of the  underlying  SIGA
shares on the date of grant.


                                       32


                        TRANSACTIONS WITH RELATED PERSONS

REVIEW, APPROVAL OR RATIFICATION OF TRANSACTIONS WITH RELATED PERSONS

      The  Company's  policies and  procedures  for  reviewing,  approving,  and
ratifying  transactions  with related persons are set forth in a written policy.
See "Annex A" to this proxy  statement  for the full  "Statement  of Policy with
respect to Related Party Transactions."

      Under these procedures,  at each calendar year's first regularly scheduled
Audit Committee  meeting,  management  recommends  related party transactions be
entered  into by the Company for that  calendar  year,  including  the  proposed
aggregate value of such  transactions,  if applicable.  After review,  the Audit
Committee  either  approves  or  disapproves  such  transactions,  and  at  each
subsequently  scheduled  meeting,  management  is  required  to update the Audit
Committee as to any material change to those proposed transactions.

      Further,  in the event  management  recommends  any further  related party
transactions  subsequent to the first calendar year meeting,  such  transactions
may be presented to the Audit  Committee for approval or  preliminarily  entered
into by management  subject to  ratification  by the Audit  Committee;  provided
that,  if  ratification  shall not be  forthcoming,  management  shall  make all
reasonable efforts to cancel or annul such transactions.

      In addition, with respect to any related party transaction that includes a
compensation  component,  management  will  submit  the  terms of such  proposed
compensation (or any subsequent  material  changes to such  compensation) to the
Compensation  Committee  for its  review.  After its  review,  the  Compensation
Committee  either  approves or  disapproves  the  compensation  component of the
related party transaction and informs management and the Audit Committee of such
approval or disapproval.

TRANSACTIONS WITH RELATED PERSONS

      Based on information provided by the directors and the executive officers,
the Audit Committee determined that there were no related person transactions to
be reported in this proxy statement other than:

      During the year ended December 31, 2006, we were billed by an affiliate of
TransTech Pharma,  for services provided in connection with the manufacturing of
our leading drug candidate, SIGA-246.

      Kramer Levin Naftalis and Frankel LLP, the Company's  legal counsel billed
the Company for legal services provided to the Company.


                                       33


                                 PROPOSAL NO. 2

                         RATIFICATION OF APPOINTMENT OF
                  INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

      The Audit  Committee of the Board of Directors  has  appointed the firm of
PricewaterhouseCoopers  LLP as SIGA's  independent  registered public accounting
firm to audit  the  financial  statements  of SIGA for the  fiscal  year  ending
December 31, 2007, and recommends  that  stockholders  vote for  ratification of
this  appointment.  PricewaterhouseCoopers  LLP  has  audited  SIGA's  financial
statements since January 1997. Representatives of PricewaterhouseCoopers LLP are
expected to be present at the Annual  Meeting and will have the  opportunity  to
make a statement  if they desire to do so, and are  expected to be  available to
respond to  appropriate  questions.  The  affirmative  vote of a majority of the
total votes cast on such  proposal  in person or by proxy at the Annual  Meeting
will be required to ratify the selection of PricewaterhouseCoopers LLP.

      If the stockholders fail to ratify the selection, the Audit Committee will
reconsider  its selection of auditors.  Even if the  selection is ratified,  the
Audit  Committee,  in its discretion,  may direct the appointment of a different
independent registered public accounting firm at any time during the year, if it
determines  that  such  change  would be in the best  interests  of SIGA and its
stockholders.

Audit Fees

      PricewaterhouseCoopers  LLP billed  SIGA  $235,000 in the  aggregate,  for
professional  services rendered by them for the audit of SIGA's annual financial
statements for the fiscal year ended  December 31, 2006,  reviews of the interim
financial  statements  included in SIGA's Forms 10-Q filed during the year ended
December 31, 2006 and consents and reviews of various  documents  filed with the
SEC during the year ended December 31, 2006.

      PricewaterhouseCoopers  LLP billed  SIGA  $184,300 in the  aggregate,  for
professional  services rendered by them for the audit of SIGA's annual financial
statements for the fiscal year ended  December 31, 2005,  reviews of the interim
financial  statements  included in SIGA's Forms 10-Q filed during the year ended
December 31, 2005 and consents and reviews of various  documents  filed with the
SEC during the year ended December 31, 2005.

Audit Related Fees

      PricewaterhouseCoopers  LLP billed  SIGA  $183,236 in the  aggregate,  for
audit related services rendered by them during the year ended December 31, 2006.

      There were no Audit Related Fees in 2005.

Tax Fees

      PricewaterhouseCoopers  LLP did not render any  professional  services for
tax  compliance,  tax advice or tax planning  during  either of the fiscal years
ended December 31, 2006 or December 31, 2005.

All Other Fees

      PricewaterhouseCoopers  LLP did not  provide  any  products  or render any
professional  services  (other  than those  covered  above under  "Audit  Fees,"
"Audited  Related  Fees" and "Tax Fees") during either of the fiscal years ended
December 31, 2006 or December 31, 2005.

Policy  on Audit  Committee  Pre-Approval  of Audit  and  Permissible  Non-Audit
Services of Independent Registered Public Accounting Firm

      The Audit  Committee's  policy is to pre-approve all audit and permissible
non-audit  services  provided by the independent  registered  public  accounting
firm.  These services may include audit services,  audit-related  services,  tax
services, and other services.

      SIGA  did not  make  use in  fiscal  year  2005 of the  rule  that  waives
pre-approval  requirements  for non-audit  services in certain cases if the fees
for these services constitute less than 5% of the total fees paid to the auditor
during the year.


                                       34


     THE BOARD OF DIRECTORS RECOMMENDS THAT THE STOCKHOLDERS VOTE "FOR" THE
     RATIFICATION (ITEM 2 OF THE ENCLOSED PROXY CARD) OF THE APPOINTMENT OF
 PRICEWATERHOUSECOOPERS LLP AS SIGA'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING
    FIRM FOR THE FISCAL YEAR ENDING DECEMBER 31, 2007.

                             STOCKHOLDER PROPOSALS

      Stockholder  proposals  to be  presented  at the 2008  Annual  Meeting  of
Stockholders, for inclusion in SIGA's proxy statement and form of proxy relating
to that meeting,  must be received by SIGA at its offices in New York, New York,
addressed to the Secretary,  not later than January 1, 2008. Such proposals must
comply  with  SIGA's  By-Laws  and the  requirements  of  Regulation  14A of the
Securities Exchange Act of 1934 (the "Exchange Act").

      In  addition,  Rule 14a-4 of the  Exchange  Act governs  SIGA's use of its
discretionary proxy voting authority with respect to a stockholder proposal that
is not  addressed  in the proxy  statement.  With  respect to SIGA's 2008 Annual
Meeting  of  Stockholders,  if  SIGA is not  provided  notice  of a  stockholder
proposal prior to March 1, 2008,  SIGA will be allowed to use its  discretionary
voting  authority  when the  proposal  is raised  at the  meeting,  without  any
discussion of the matter in the proxy statement.

                              SECTION 16 BENEFICIAL
                         OWNERSHIP REPORTING COMPLIANCE

      Section 16(a) of the Exchange Act requires  SIGA's officers and directors,
and persons who own more than ten percent of a registered class of SIGA's equity
securities,  to file  reports of  ownership  and changes in  ownership  with the
Securities  and  Exchange  Commission.  Officers,  directors  and  greater  than
ten-percent  stockholders  are required by  Securities  and Exchange  Commission
regulation  to furnish SIGA with copies of all Section  16(a)  reports that they
file.

      Based solely upon review of the copies of such  reports  furnished to SIGA
and  written  representations  from  certain of SIGA's  executive  officers  and
directors  that no other such reports were  required,  SIGA believes that during
the fiscal year ended  December  31,  2006,  each of the  following  individuals
failed to file on a timely  basis one  report  relating  to one  transaction  as
required by Section 16 of the exchange Act: Dr. Rose, Mr. Antal, Mr.  Constance,
Mr.  Drapkin,  Dr. Hammer,  Dr. Mjalli,  Dr. Oz, Mr. Savas,  Ms. Slotkin and Dr.
Weiner. All reports were subsequently filed.

           AVAILABILITY OF ANNUAL REPORT AND FORM 10-K TO STOCKHOLDERS

      SIGA's Annual Report to Stockholders  for the year ended December 31, 2006
accompanies  this proxy statement.  SIGA will provide to any  stockholder,  upon
written  request and without  charge,  a copy of its most recent  Report on Form
10-K,  including  the financial  statements,  as filed with the  Securities  and
Exchange  Commission.  All requests  for such reports  should be directed to the
Chief Financial  Officer,  420 Lexington  Avenue,  Suite 408, New York, New York
10170, telephone number (212) 672-9100.

                                  OTHER MATTERS

      At the date of this  proxy  statement,  management  was not aware that any
matters not referred to in this proxy statement would be presented for action at
the Annual Meeting.  If any other matters should come before the Annual Meeting,
the persons named in the accompanying proxy will have discretionary authority to
vote all  proxies  in  accordance  with their best  judgment,  unless  otherwise
restricted by law.

                                              BY ORDER OF THE BOARD OF DIRECTORS


                                              /s/ Thomas N. Konatich
                                              ----------------------
                                              Thomas N. Konatich
                                              Secretary

Dated: April 27, 2007


                                       35


                             SIGA TECHNOLOGIES, INC.
                    PROXY SOLICITED BY THE BOARD OF DIRECTORS
                     FOR THE ANNUAL MEETING OF STOCKHOLDERS
                           TO BE HELD ON MAY 30, 2007

      The  undersigned  hereby appoints Thomas N. Konatich as attorney and proxy
of the undersigned,  with full power of substitution,  to vote all of the shares
of stock of SIGA  Technologies,  Inc. which the  undersigned  may be entitled to
vote at the Annual Meeting of Stockholders of SIGA Technologies, Inc. to be held
at the  offices of Kramer  Levin  Naftalis  & Frankel  LLP,  1177  Avenue of the
Americas,  29th floor, New York, New York 10036, on Wednesday,  May 30, 2007, at
10:00 a.m. (local time),  and at any and all  postponements,  continuations  and
adjournments  thereof,  with all powers that the  undersigned  would  possess if
personally  present,  upon  and in  respect  of  the  following  matters  and in
accordance with the following  instructions,  with discretionary authority as to
any and all other matters that may properly come before the meeting.

UNLESS A  CONTRARY  DIRECTION  IS  INDICATED,  THIS  PROXY WILL BE VOTED FOR ALL
NOMINEES   LISTED   IN   PROPOSAL   NO.   1,   AND  FOR  THE   RATIFICATION   OF
PRICEWATERHOUSECOOPERS  LLP AS THE INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
OF SIGA TECHNOLOGIES,  INC. FOR THE FISCAL YEAR ENDING DECEMBER 31, 2007 AS MORE
SPECIFICALLY  DESCRIBED IN THE PROXY  STATEMENT.  IF SPECIFIC  INSTRUCTIONS  ARE
INDICATED, THIS PROXY WILL BE VOTED IN ACCORDANCE THEREWITH.

THE BOARD OF  DIRECTORS  RECOMMENDS A VOTE "FOR" THE  DIRECTOR  NOMINEES  LISTED
BELOW, AND "FOR" THE SELECTION OF PRICEWATERHOUSECOOPERS  LLP AS THE INDEPENDENT
REGISTERED PUBLIC ACCOUNTING FIRM OF SIGA TECHNOLOGIES, INC. FOR THE FISCAL YEAR
ENDING DECEMBER 31, 2007

PLEASE VOTE,  SIGN,  DATE AND RETURN PROMPTLY IN THE ENCLOSED  ENVELOPE.  PLEASE
MARK YOUR VOTE IN BLUE OR BLACK INK AS SHOWN HERE: |X|

1.    To elect ten directors.

      |_|   FOR ALL NOMINEES

      |_|   WITHHOLD AUTHORITY FOR ALL NOMINEES

      |_|   FOR ALL EXCEPT (See instructions below)

         NOMINEES: ( )  Eric A. Rose, M.D.

                   ( )  Thomas E. Constance

                   ( )  Adnan M. Mjalli, Ph.D.



                   ( )  Mehmet C. Oz, M.D.

                   ( )  Steven L. Fasman

                   ( )  Paul G. Savas

                   ( )  Michael A. Weiner, M.D.

                   ( )  Judy S. Slotkin

                   ( )  James J. Antal

                   ( )  Scott M. Hammer, M.D.

         INSTRUCTION: To withhold authority to vote for any individual
         nominee(s), mark "FOR ALL EXCEPT" and fill in circle next to each
         nominee you wish to withhold, as shown here: ( )

2.    To ratify the selection of  PricewaterhouseCoopers  LLP as the independent
      registered  public  accounting  firm of SIGA  Technologies,  Inc.  for the
      fiscal year ending December 31, 2007.

      |_|  FOR                  |_| AGAINST               |_| ABSTAIN

THIS PROXY IS SOLICITED ON BEHALF OF THE BOARD OF  DIRECTORS.  IT MAY BE REVOKED
PRIOR TO ITS EXERCISE.

RECEIPT  OF  NOTICE  OF  THE  ANNUAL  MEETING  AND  PROXY  STATEMENT  IS  HEREBY
ACKNOWLEDGED,  AND THE  TERMS OF THE  NOTICE  AND  PROXY  STATEMENT  ARE  HEREBY
INCORPORATED BY REFERENCE INTO THIS PROXY.  THE  UNDERSIGNED  HEREBY REVOKES ALL
PROXIES  HERETOFORE  GIVEN  FOR  SAID  MEETING  OR  ANY  AND  ALL  ADJOURNMENTS,
POSTPONEMENTS AND CONTINUATIONS THEREOF.

PLEASE VOTE,  DATE,  SIGN AND PROMPTLY  RETURN THIS PROXY IN THE ENCLOSED RETURN
ENVELOPE WHICH IS POSTAGE PREPAID IF MAILED IN THE UNITED STATES.

____________________________________________________________________________

To  change  the  address  on your  account,  please  check  the box at right and
indicate your new address in the address  space above.  Please note that changes
to the  registered  name(s) on the account may not be submitted via this method.
|_|


Signature of Stockholder: ______________________________________________________

Date: ________________


Signature of Stockholder: ______________________________________________________

Date: ________________

PLEASE SIGN  EXACTLY AS YOUR NAME  APPEARS ON THIS PROXY.  WHERE SHARES ARE HELD
JOINTLY,  EACH HOLDER  SHOULD SIGN.  WHEN  SIGNING AS  EXECUTOR,  ADMINISTRATOR,
ATTORNEY,  TRUSTEE OR GUARDIAN,  PLEASE GIVE FULL TITLE AS SUCH.  IF SIGNER IS A
CORPORATION,  PLEASE SIGN IN FULL  CORPORATE  NAME BY DULY  AUTHORIZED  OFFICER,
GIVING  FULL  TITLE AS SUCH.  IF SIGNER IS A  PARTNERSHIP,  PLEASE  SIGN IN FULL
PARTNERSHIP NAME BY AUTHORIZED PERSON.




                                                                         Annex A


                             SIGA TECHNOLOGIES, INC.

              STATEMENT OF POLICIES AND PROCEDURES WITH RESPECT TO
                           RELATED PARTY TRANSACTIONS

I.    Introduction

      The board of directors (the "Board of  Directors")  of SIGA  Technologies,
Inc.  (the  "Company")  recognizes  that related  party  transactions  present a
heightened  risk of  conflicts  of interest  and/or the  perception  of improper
valuation. Therefore, the Board of Directors adopted this policy, which shall be
followed  in  connection  with all  related  party  transactions  involving  the
Company.

      A. Under this policy, any "Related Party Transaction" shall be consummated
or shall continue only if:

      1.    the  Audit  Committee  of the Board of  Directors  has  approved  or
            ratified such  transaction  in accordance  with the  guidelines  set
            forth in the policy and if the transaction is on terms comparable to
            those  that  could be  obtained  in arm's  length  dealings  with an
            unrelated third party; and

      2.    the transaction involves  compensation,  such that the terms of such
            compensation have been approved by the Compensation Committee of the
            Board of Directors.

      B. For these purposes, a "Related Party" is:

      1.    any  director,  nominee  for  director or  executive  officer of the
            Company;

      2.    any immediate  family member of a director,  nominee for director or
            executive  officer of the  Company  (meaning  any child,  stepchild,
            parent, stepparent, spouse, sibling,  mother-in-law,  father-in-law,
            son-in-law, daughter-in-law, brother-in-law or sister-in-law of such
            person, and any person (other than a tenant or employee) sharing the
            household of such person);

      3.    any person (or  "group" as that term is used in Section  13(d)(3) of
            the  Securities  Exchange  Act of 1934,  as amended  (the  "Exchange
            Act")) who is the beneficial  owner of more than 5% of the Company's
            voting securities;

      4.    any immediate  family member of a person (or "group" as that term is
            used in Section  13(d)(3) of the Exchange Act) who is the beneficial
            owner of more than 5% of the Company's  voting  securities  (meaning
            any  child,   stepchild,   parent,   stepparent,   spouse,  sibling,
            mother-in-law, father-in-law, son-in-law,



            daughter-in-law, brother-in-law or sister-in-law of such person, and
            any person  (other than a tenant or employee)  sharing the household
            of such person); or

      5.    an entity that is owned or controlled  by someone  listed in 1, 2, 3
            or 4 above,  or an  entity in which  someone  listed in 1, 2, 3 or 4
            above  has a  substantial  ownership  interest  or  control  of such
            entity.

      C. For these  purposes,  a "Related  Party  Transaction"  is a transaction
between the Company and any Related Party (including,  without  limitation,  any
transactions  requiring  disclosure  under Item 404 of Regulation  S-K under the
Exchange Act), other than:

      1.    transactions available to all employees generally; or

      2.    transactions  involving  less than $5,000 when  aggregated  with all
            similar transactions.

II.   Committee Approval

      A. Audit  Committee  Approval.  The Board of Directors has determined that
the  Audit  Committee  is best  suited  to  review  and  approve  Related  Party
Transactions.  Accordingly,  at each calendar year's first  regularly  scheduled
Audit Committee  meeting,  management shall recommend Related Party Transactions
be entered into by the Company for that  calendar  year,  including the proposed
aggregate value of such transactions, if applicable. After its review, the Audit
Committee shall approve or disapprove such transactions and at each subsequently
scheduled  meeting,  management  shall  update  the  Audit  Committee  as to any
material  change  to  those  proposed  transactions.  In  the  event  management
recommends  any  further  Related  Party  Transactions  subsequent  to the first
calendar year meeting, such transactions may be presented to the Audit Committee
for approval or preliminarily entered into by management subject to ratification
by the Audit Committee; provided that, if ratification shall not be forthcoming,
management   shall  make  all  reasonable   efforts  to  cancel  or  annul  such
transactions.

      B. Compensation  Committee Approval. The Board of Directors has determined
that, if a Related Party Transaction involves compensation,  it is advisable and
appropriate  for  the  Compensation  Committee  to  review  and  approve  of the
compensation  components of all Related Party  Transactions.  Accordingly,  with
respect to any Related Party Transaction that includes a compensation component,
management  will  submit  the  terms  of  such  proposed  compensation  (or  any
subsequent material changes to such compensation) to the Compensation  Committee
for its review.  After its review,  the Compensation  Committee shall approve or
disapprove  the  compensation  component of the Related  Party  Transaction  and
inform management and the Audit Committee of such approval or disapproval.

III.  Disclosure

      The Securities Act of 1933, as amended,  the Exchange Act, and the related
rules and regulations  promulgated  thereunder require the disclosure of certain
Related Party Transactions



in the  Company's  filings  with the  Securities  and Exchange  Commission.  All
Related Party  Transactions  are to be disclosed to the extent  required by law,
rule or regulation in the Company's applicable filings. Furthermore, all Related
Party Transactions shall be disclosed to the Audit Committee (and, to the extent
they include a compensation component, to the Compensation  Committee),  and any
material  Related  Party  Transaction  shall be  disclosed  to the full Board of
Directors.

IV.   Other Agreements

      Management  shall ensure that all Related Party  Transactions are approved
in accordance with any  requirements of the Company's  financing  agreements (if
any).