Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
William Blair Capital Management VII, LLC
  2. Issuer Name and Ticker or Trading Symbol
NUVASIVE INC [NUVA]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director __X__ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
303 W. MADISON, SUITE 2500
3. Date of Earliest Transaction (Month/Day/Year)
06/14/2005
(Street)

CHICAGO, IL 60606
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
___ Form filed by One Reporting Person
_X_ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 06/14/2005   J(1)   2,000,000 (2) D (1) 795,880 I See footnote (3)
Common Stock 06/14/2005   J(1)   200,119 (4) A (1) 995,999 I See footnote (3)
Common Stock 06/14/2005   J(5)   200,119 (4) D (5) 795,880 I See footnote (3)
Common Stock 06/14/2005   J(5)   248 (6) A (5) 796,128 I See footnote (3)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
William Blair Capital Management VII, LLC
303 W. MADISON, SUITE 2500
CHICAGO, IL 60606
    X    
William Blair Capital Management VII, LP
303 W. MADISON, SUITE 2500
CHICAGO, IL 60606
    X    
BLAIR WILLIAM CAPITAL PARTNERS VII QP LP
303 W. MADISON, SUITE 2500
CHICAGO, IL 60606
    X    
BLAIR WILLIAM CAPITAL PARTNERS VII LP
303 W. MADISON, SUITE 2500
CHICAGO, IL 60606
    X    

Signatures

 /s/ Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C.   06/14/2005
**Signature of Reporting Person Date

 /s/ Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P.   06/14/2005
**Signature of Reporting Person Date

 /s/ Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P., the general partner of William Blair Capital Partners VII QP, L.P.   06/14/2005
**Signature of Reporting Person Date

 /s/ Arda M. Minocherhomjee, Managing Director of William Blair Capital Management VII, L.L.C., the general partner of William Blair Capital Management VII, L.P., the general partner of William Blair Capital Partners VII, L.P.   06/14/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Pro rata distribution of shares by William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P. to their partners.
(2) Represents 1,925,781 shares directly owned by William Blair Capital Partners VII QP, L.P. and 74,219 shares directly owned by William Blair Capital Partners VII, L.P.
(3) William Blair Capital Management VII, L.P. is the general partner of William Blair Capital Partners VII QP, L.P. and William Blair Capital Partners VII, L.P. William Blair Capital Management VII, L.L.C. is the general partner of William Blair Capital Management VII, L.P. Accordingly, William Blair Capital Management VII, L.P. and William Blair Capital Management VII, L.L.C. may be deemed beneficial owners of the shares listed in Table 1; however, William Blair Capital Management VII, L.P. and William Blair Capital Management VII, L.L.C. disclaim beneficial ownership of these shares except to the extent of their proportionate pecuniary interest in these shares.
(4) Represents shares directly owned by William Blair Capital Management VII, L.P.
(5) Pro rata distribution of shares by William Blair Capital Management VII, L.P. to its partners.
(6) Represents shares directly owned by William Blair Capital Management VII, L.L.C.

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