Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Expires: January 31, 2005
Estimated average burden hours per response... 0.5

(Print or Type Responses)
1. Name and Address of Reporting Person *
MCCOY JOHN B
  2. Issuer Name and Ticker or Trading Symbol
CARDINAL HEALTH INC [CAH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
191 W. NATIONWIDE BLVD., SUITE 625
3. Date of Earliest Transaction (Month/Day/Year)
03/28/2005
(Street)

COLUMBUS, OH 43215
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 03/28/2005   M   3,132 A $ 15.967 3,132 D  
Common Shares               4,013 I By Deferred Compensation Plan
Common Shares               34,137 I By FLITE Trust
Common Shares               6,436 I By trust FBO his son
Common Shares               50,773 I By GRAT

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (right to buy) (1) $ 15.967 03/28/2005   M     1 11/14/1995 11/14/2005 Common Shares 3,132 (4) 0 D  
Option (right to buy) (2) $ 23.407             10/29/1996 10/29/2006 Common Shares 2,138   1 D  
Option (right to buy) (2) $ 33.28             11/05/1997 11/05/2007 Common Shares 3,005   1 D  
Option (right to buy) (2) $ 46.293             11/23/1998 11/23/2008 Common Shares 2,160   1 D  
Option (right to buy) (2) $ 29.958             11/03/1999 11/03/2009 Common Shares 3,338   1 D  
Option (right to buy) (2) $ 62.5             11/01/2000 11/01/2010 Common Shares 2,064   1 D  
Option (right to buy) (3) $ 62.5             11/01/2000 11/01/2010 Common Shares 1,136   1 D  
Option (right to buy) (2) $ 63.9             11/07/2001 11/07/2011 Common Shares 2,019   1 D  
Option (right to buy) (3) $ 63.9             11/07/2001 11/07/2011 Common Shares 1,893   1 D  
Option (right to buy) (2) $ 70.01             11/06/2002 11/06/2012 Common Shares 1,843   1 D  
Option (right to buy) (3) $ 70.01             11/06/2002 11/06/2012 Common Shares 1,728   1 D  
Option (right to buy) (2) $ 59             11/05/2003 11/05/2013 Common Shares 2,842   1 D  
Option (right to buy) (3) $ 59             11/05/2003 11/05/2013 Common Shares 2,242   1 D  
Option (right to buy) (2) $ 54.2             12/08/2004 12/08/2014 Common Shares 3,094   1 D  
Option (right to buy) (3) $ 54.2             12/08/2004 12/08/2014 Common Shares 2,441   1 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
MCCOY JOHN B
191 W. NATIONWIDE BLVD.
SUITE 625
COLUMBUS, OH 43215
  X      

Signatures

 John B. McCoy   03/28/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Stock option granted pursuant to the Cardinal Health, Inc. Directors' Stock Option Plan.
(2) Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan.
(3) Stock option granted pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.
(4) Stock option was disposed of in connection with its exercise for no additional consideration beyond the option shares.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.