FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * FOTIADES GEORGE L   2. Issuer Name and Ticker or Trading Symbol CARDINAL HEALTH INC [CAH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) President & COO (Last) (First) (Middle) 7000 CARDINAL PLACE 3. Date of Earliest Transaction (Month/Day/Year) 05/31/2005 (Street) DUBLIN, OH 43017 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 05/31/2005   M(1)   73,245 A $ 38.287 153,645 D   Common Shares 05/31/2005   S(1)   73,245 D $ 57.7695 (4) 80,400 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Option (right to buy) (2)

$ 38.287

05/31/2005

M

1

06/01/2001

06/02/2005

Common Shares

73,245

(5)

0

D

Option (right to buy) (3)

$ 41.553

09/16/2001

09/16/2008

Common Shares

56,250

1

D

Option (right to buy) (3)

$ 47.333

03/01/2002

03/01/2009

Common Shares

27,171

1

D

Option (right to buy) (3)

$ 31.167

11/15/2002

11/15/2009

Common Shares

67,907

1

D

Option (right to buy) (3)

$ 66.083

11/20/2003

11/20/2010

Common Shares

60,530

1

D

Option (right to buy) (3)

$ 68.1

11/19/2004

11/19/2011

Common Shares

67,915

1

D

Option (right to buy) (3)

$ 67.9

11/18/2005

11/18/2012

Common Shares

250,000

1

D

Option (right to buy) (3)

$ 64.11

01/31/2007

02/01/2014

Common Shares

225,000

1

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
FOTIADES GEORGE L 7000 CARDINAL PLACE DUBLIN, OH 43017			President & COO

Signatures

George L. Fotiades		05/31/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The exercise and sale reported on this Form 4 were effected pursuant to a 10b5-1 plan established by the reporting person on November 10, 2004, when the reporting person was not aware of material non-public information about the Company. The stock option exercised pursuant to the 10b5-1 plan would have expired on June 2, 2005, if not exercised.
(2)	Stock option granted pursuant to the R.P. Scherer Stock Option Plan.
(3)	Stock option granted pursuant to the Cardinal health, Inc. Equity Incentive Plan.
(4)	Weighted average sale price from 27 different transactions with the price ranging from $57.67 to $57.94. The details of these transactions are as follows: 5,000 shares at $57.67, 100 shares at $57.68, 200 shares at $57.69, 3,000 shares at $57.70, 3,800 shares at $57.71, 2,500 shares at $57.72, 3,900 shares at $57.73, 3,100 shares at $57.74, 16,400 shares at $57.75, 1,600 shares at $57.76, 7,800 shares at $57.77, 700 shares at $57.78, 1,600 shares at $57.79, 1,800 shares at $57.80, 4,100 shares at $57.81, 5,400 shares at $57.82, 600 shares at $57.83, 3,445 shares at $57.84, 900 shares at $57.85, 2,600 shares at $57.86, 2,500 shares at $57.87, 400 shares at $57.88, 600 shares at $57.89, 400 shares at $57.90, 600 shares at $57.91, 100 shares at $57.93 and 100 shares at $57.94.
(5)	Stock option was disposed of in connection with its exercise for no additional consideration beyond the option shares.

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