FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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1. Name and Address of Reporting Person * WALTER ROBERT D   2. Issuer Name and Ticker or Trading Symbol CARDINAL HEALTH INC [CAH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) Chairman and CEO (Last) (First) (Middle) 7000 CARDINAL PLACE 3. Date of Earliest Transaction (Month/Day/Year) 09/12/2005 (Street) DUBLIN, OH 43017 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 09/12/2005   S(1)   10,000 (1) D $ 59.6 1,574,375 (2) D   Common Shares               2,826 I By ESPP Common Shares               432,010 (3) I By GRAT IX Common Shares               470,000 I By LLC (5) Common Shares               608,603 (4) I By GRAT X Common Shares               300,000 I By LLC II (5) Common Shares               700,000 I By GRAT XI

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Option (right to buy) (6)

$ 17.74

03/04/1999

03/04/2006

Common Shares

89,207

1

D

Option (right to buy) (6)

$ 27.053

03/03/2000

03/03/2007

Common Shares

100,409

1

D

Option (right to buy) (6)

$ 27.14

07/21/2000

07/21/2007

Common Shares

45,000

1

D

Option (right to buy) (6)

$ 36.307

03/02/2001

03/02/2008

Common Shares

96,402

1

D

Option (right to buy) (6)

$ 43.14

08/11/2001

08/11/2008

Common Shares

135,000

1

D

Option (right to buy) (6)

$ 47.333

03/01/2002

03/01/2009

Common Shares

187,500

1

D

Option (right to buy) (6)

$ 31.167

(7)

11/15/2009

Common Shares

562,500

1

D

Option (right to buy) (6)

$ 66.083

11/20/2003

11/20/2010

Common Shares

272,384

1

D

Option (right to buy) (6)

$ 68.1

01/15/2006

11/19/2011

Common Shares

440,529

1

D

Option (right to buy) (6)

$ 67.9

11/18/2005

11/18/2012

Common Shares

486,009

1

D

Option (right to buy) (6)

$ 61.38

11/17/2006

11/17/2013

Common Shares

507,086

1

D

Option (right to buy) (6)

$ 44.15

08/23/2007

08/23/2014

Common Shares

562,500

1

D

Stock Appreciation Right (8)

$ 44.15

08/23/2007

08/23/2014

Common Shares

142,483

1

D

Stock Appreciation Right (9)

$ 31.167

08/03/2005

(10)

Common Shares

862,500

1

D

Option (right to buy) (6)

$ 58.88

(11)

09/02/2012

Common Shares

379,759

1

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
WALTER ROBERT D 7000 CARDINAL PLACE DUBLIN, OH 43017	X		Chairman and CEO

Signatures

Robert D. Walter		09/12/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The sale reported on this Form 4 was effected pursuant to a 10b5-1 plan established by the reporting person on March 1, 2005, when the reporting person was not aware of material non-public information about the Company.
(2)	300 of these shares were previously reported as indirectly beneficially owned by LLC, and were transferred to direct beneficial ownership on September 12, 2005.
(3)	12,900 of these shares were previously reported as indirectly beneficially owned by LLC, and were transferred to GRAT IX on September 12, 2005.
(4)	16,800 of these shares were previously reported as indirectly benefically owned by LLC and were transferred to GRAT X on September 12, 2005.
(5)	The reporting person holds the controlling interest in, and is the sole manager of, the LLC.
(6)	Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan (the "Equity Incentive Plan").
(7)	Stock option vested in three equal annual installments beginning on 11/15/00.
(8)	Deferred Payment Stock Appreciation Right granted in partial fulfillment of the Company's obligations to the reporting person pursuant to the Employment Agreement.
(9)	Deferred Payment Stock Appreciation Right granted to compensate the reporting person for the portion of the option to purchase 1,425,000 common shares originally granted to the reporting person on November 15, 1999 (the "November 1999 Option"), which portion has subsequently been determined to be null and void.
(10)	Expires on the earlier of (x) November 15, 2009 (the expiration date of the November 1999 Option) or (y) six months after the reporting person's termination of employment.
(11)	Stock option vests in four equal annual installments beginning on 9/2/2006.

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