Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
WALTER ROBERT D
  2. Issuer Name and Ticker or Trading Symbol
CARDINAL HEALTH INC [CAH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chairman and CEO
(Last)
(First)
(Middle)
7000 CARDINAL PLACE
3. Date of Earliest Transaction (Month/Day/Year)
09/12/2005
(Street)

DUBLIN, OH 43017
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 09/12/2005   S(1)   10,000 (1) D $ 59.6 1,574,375 (2) D  
Common Shares               2,826 I By ESPP
Common Shares               432,010 (3) I By GRAT IX
Common Shares               470,000 I By LLC (5)
Common Shares               608,603 (4) I By GRAT X
Common Shares               300,000 I By LLC II (5)
Common Shares               700,000 I By GRAT XI

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (right to buy) (6) $ 17.74             03/04/1999 03/04/2006 Common Shares 89,207   1 D  
Option (right to buy) (6) $ 27.053             03/03/2000 03/03/2007 Common Shares 100,409   1 D  
Option (right to buy) (6) $ 27.14             07/21/2000 07/21/2007 Common Shares 45,000   1 D  
Option (right to buy) (6) $ 36.307             03/02/2001 03/02/2008 Common Shares 96,402   1 D  
Option (right to buy) (6) $ 43.14             08/11/2001 08/11/2008 Common Shares 135,000   1 D  
Option (right to buy) (6) $ 47.333             03/01/2002 03/01/2009 Common Shares 187,500   1 D  
Option (right to buy) (6) $ 31.167               (7) 11/15/2009 Common Shares 562,500   1 D  
Option (right to buy) (6) $ 66.083             11/20/2003 11/20/2010 Common Shares 272,384   1 D  
Option (right to buy) (6) $ 68.1             01/15/2006 11/19/2011 Common Shares 440,529   1 D  
Option (right to buy) (6) $ 67.9             11/18/2005 11/18/2012 Common Shares 486,009   1 D  
Option (right to buy) (6) $ 61.38             11/17/2006 11/17/2013 Common Shares 507,086   1 D  
Option (right to buy) (6) $ 44.15             08/23/2007 08/23/2014 Common Shares 562,500   1 D  
Stock Appreciation Right (8) $ 44.15             08/23/2007 08/23/2014 Common Shares 142,483   1 D  
Stock Appreciation Right (9) $ 31.167             08/03/2005   (10) Common Shares 862,500   1 D  
Option (right to buy) (6) $ 58.88               (11) 09/02/2012 Common Shares 379,759   1 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
WALTER ROBERT D
7000 CARDINAL PLACE
DUBLIN, OH 43017
  X     Chairman and CEO  

Signatures

 Robert D. Walter   09/12/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The sale reported on this Form 4 was effected pursuant to a 10b5-1 plan established by the reporting person on March 1, 2005, when the reporting person was not aware of material non-public information about the Company.
(2) 300 of these shares were previously reported as indirectly beneficially owned by LLC, and were transferred to direct beneficial ownership on September 12, 2005.
(3) 12,900 of these shares were previously reported as indirectly beneficially owned by LLC, and were transferred to GRAT IX on September 12, 2005.
(4) 16,800 of these shares were previously reported as indirectly benefically owned by LLC and were transferred to GRAT X on September 12, 2005.
(5) The reporting person holds the controlling interest in, and is the sole manager of, the LLC.
(6) Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan (the "Equity Incentive Plan").
(7) Stock option vested in three equal annual installments beginning on 11/15/00.
(8) Deferred Payment Stock Appreciation Right granted in partial fulfillment of the Company's obligations to the reporting person pursuant to the Employment Agreement.
(9) Deferred Payment Stock Appreciation Right granted to compensate the reporting person for the portion of the option to purchase 1,425,000 common shares originally granted to the reporting person on November 15, 1999 (the "November 1999 Option"), which portion has subsequently been determined to be null and void.
(10) Expires on the earlier of (x) November 15, 2009 (the expiration date of the November 1999 Option) or (y) six months after the reporting person's termination of employment.
(11) Stock option vests in four equal annual installments beginning on 9/2/2006.

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