FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL OMB Number: 3235-0287 Expires: January 31, 2005 Estimated average burden hours per response... 0.5

(Print or Type Responses)

1. Name and Address of Reporting Person * LOSH J MICHAEL   2. Issuer Name and Ticker or Trading Symbol CARDINAL HEALTH INC [CAH] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) (Last) (First) (Middle) 1711 HERON RIDGE DR. 3. Date of Earliest Transaction (Month/Day/Year) 11/02/2005 (Street) BLOOMFIELD HILLS, MI 48302 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Shares 11/02/2005   A   485 A (1) 3,860 D   Common Shares               1,500 I In Trust FBO Daughters (2) Common Shares 11/02/2005   A   282 A $ 62.07 3,575 I By Deferred Compensation Plan

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
	Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.		SEC 1474 (9-02)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Option (right to buy) (3)

$ 19.147

05/15/1996

05/15/2006

Common Shares

5,223

1

D

Option (right to buy) (3)

$ 46.293

11/23/1998

11/23/2008

Common Shares

2,160

1

D

Option (right to buy) (3)

$ 29.958

11/03/1999

11/03/2009

Common Shares

3,338

1

D

Option (right ty buy) (3)

$ 62.5

11/01/2000

11/01/2010

Common Shares

2,064

1

D

Option (right to buy) (4)

$ 62.5

11/01/2000

11/01/2010

Common Shares

1,136

1

D

Option (right to buy) (3)

$ 63.9

11/07/2001

11/07/2011

Common Shares

2,019

1

D

Option (right to buy) (4)

$ 63.9

11/07/2001

11/07/2011

Common Shares

1,893

1

D

Option (right to buy) (3)

$ 70.01

11/06/2002

11/06/2012

Common Shares

1,843

1

D

Option (right to buy) (4)

$ 70.01

11/06/2002

11/06/2012

Common Shares

1,728

1

D

Option (right to buy) (3)

$ 59

11/05/2003

11/05/2013

Common Shares

2,842

1

D

Option (right to buy) (4)

$ 59

11/05/2003

11/05/2013

Common Shares

2,242

1

D

Option (right to buy) (3)

$ 44

07/27/2007

07/27/2014

Common Shares

210,000 (5)

1

D

Option (right to buy) (3)

$ 61.79

11/02/2005

A

1

11/02/2006

11/02/2012

Common Shares

2,714

(6)

1

D

Option (right to buy) (4)

$ 61.79

11/02/2005

A

1

11/02/2006

11/02/2012

Common Shares

684

(6)

1

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
LOSH J MICHAEL 1711 HERON RIDGE DR. BLOOMFIELD HILLS, MI 48302	X

Signatures

J.Michael Losh		11/02/2005
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	Restricted share unit award granted without payment by grantee pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.
(2)	The filing of this statement shall not be construed as an admission that Mr. Losh is, for the purpose of Section 16 of the Securities Exchange Act of 1934, as amended, the beneficial owner of these shares.
(3)	Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan.
(4)	Stock option granted pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.
(5)	Stock option granted for compensation as Chief Financial Officer on an interim basis in lieu of cash, salary, bonus or other incentive compensation.
(6)	Stock option granted without payment by grantee.

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.