Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
LOSH J MICHAEL
  2. Issuer Name and Ticker or Trading Symbol
CARDINAL HEALTH INC [CAH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
1711 HERON RIDGE DR.
3. Date of Earliest Transaction (Month/Day/Year)
11/02/2005
(Street)

BLOOMFIELD HILLS, MI 48302
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 11/02/2005   A   485 A (1) 3,860 D  
Common Shares               1,500 I In Trust FBO Daughters (2)
Common Shares 11/02/2005   A   282 A $ 62.07 3,575 I By Deferred Compensation Plan

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (right to buy) (3) $ 19.147             05/15/1996 05/15/2006 Common Shares 5,223   1 D  
Option (right to buy) (3) $ 46.293             11/23/1998 11/23/2008 Common Shares 2,160   1 D  
Option (right to buy) (3) $ 29.958             11/03/1999 11/03/2009 Common Shares 3,338   1 D  
Option (right ty buy) (3) $ 62.5             11/01/2000 11/01/2010 Common Shares 2,064   1 D  
Option (right to buy) (4) $ 62.5             11/01/2000 11/01/2010 Common Shares 1,136   1 D  
Option (right to buy) (3) $ 63.9             11/07/2001 11/07/2011 Common Shares 2,019   1 D  
Option (right to buy) (4) $ 63.9             11/07/2001 11/07/2011 Common Shares 1,893   1 D  
Option (right to buy) (3) $ 70.01             11/06/2002 11/06/2012 Common Shares 1,843   1 D  
Option (right to buy) (4) $ 70.01             11/06/2002 11/06/2012 Common Shares 1,728   1 D  
Option (right to buy) (3) $ 59             11/05/2003 11/05/2013 Common Shares 2,842   1 D  
Option (right to buy) (4) $ 59             11/05/2003 11/05/2013 Common Shares 2,242   1 D  
Option (right to buy) (3) $ 44             07/27/2007 07/27/2014 Common Shares 210,000 (5)   1 D  
Option (right to buy) (3) $ 61.79 11/02/2005   A   1   11/02/2006 11/02/2012 Common Shares 2,714 (6) 1 D  
Option (right to buy) (4) $ 61.79 11/02/2005   A   1   11/02/2006 11/02/2012 Common Shares 684 (6) 1 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
LOSH J MICHAEL
1711 HERON RIDGE DR.
BLOOMFIELD HILLS, MI 48302
  X      

Signatures

 J.Michael Losh   11/02/2005
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Restricted share unit award granted without payment by grantee pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.
(2) The filing of this statement shall not be construed as an admission that Mr. Losh is, for the purpose of Section 16 of the Securities Exchange Act of 1934, as amended, the beneficial owner of these shares.
(3) Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan.
(4) Stock option granted pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.
(5) Stock option granted for compensation as Chief Financial Officer on an interim basis in lieu of cash, salary, bonus or other incentive compensation.
(6) Stock option granted without payment by grantee.

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