Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
WALTER MATTHEW D
  2. Issuer Name and Ticker or Trading Symbol
CARDINAL HEALTH INC [CAH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
5200 RINGS ROAD
3. Date of Earliest Transaction (Month/Day/Year)
05/15/2006
(Street)

DUBLIN, OH 43017
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 01/11/2006   G V 340 A (1) 162,094 (2) D  
Common Shares 01/12/2006   G V 1,002 D (1) 161,092 D  
Common Shares 01/11/2006   G V 1,020 A (1) 7,860 I By trusts FBO children
Common Shares 01/12/2006   G V 1,002 A (1) 8,862 I By trusts FBO children
Common Shares 01/11/2006   G V 340 A (1) 1,430 I By spouse
Common Shares               34,502 I By DGT Trust (4)
Common Shares 05/15/2006   S   6,997 (3) D $ 67.8 24,100 I By Matthew D. Walter Trust (5)
Common Shares               1,112,663 I By LLC (6)
Common Shares               54,033 I By GRAT I

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (right to buy) (7) $ 70.3             05/01/2002 05/01/2012 Common Shares 2,134   1 D  
Option (right to buy) (8) $ 70.3             05/01/2002 05/01/2012 Common Shares 1,422   1 D  
Option (right to buy) (8) $ 70.01             11/06/2002 11/06/2012 Common Shares 3,571   1 D  
Option (right to buy) (8) $ 59             11/05/2003 11/05/2013 Common Shares 5,084   1 D  
Option (right to buy) (7) $ 54.2             12/08/2004 12/08/2014 Common Shares 3,094   1 D  
Option (right to buy) (8) $ 54.2             12/08/2004 12/08/2014 Common Shares 2,441   1 D  
Option (right to buy) (7) $ 61.79             11/02/2006 11/02/2012 Common Shares 2,714   1 D  
Option (right to buy) (8) $ 61.79             11/02/2006 11/02/2012 Common Shares 684   1 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
WALTER MATTHEW D
5200 RINGS ROAD
DUBLIN, OH 43017
  X      

Signatures

 Matthew D. Walter   05/17/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Bona fide gift.
(2) 30,856 of these shares were previously reported as indirectly beneficially owned through GRAT I and were subsequently transferred to direct beneficial ownership on January 27, 2006.
(3) Bank One Trust Company, N.A. ("Bank One Trust") serves as the trustee of the MDW Trust, which was established in 1987 for the benefit of the reporting person. This transaction was initiated solely by Bank One Trust in the independent exercise of its discretion as trustee.
(4) Reporting person holds a one-third economic interest in, and is a co-trustee of, the DGT Trust.
(5) Shares held in the MDW Trust of which the reporting person is the primary beneficiary and pursuant to which the reporting person may withdraw proceeds at certain specified times.
(6) Reporting person holds a one-third economic interest in, and is the manager of, the LLC.
(7) Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan.
(8) Stock option granted pursuant to the Cardinal Health, Inc. Outside Directors Equity Incentive Plan.

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