Ownership Submission
FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
LABRUM RONALD K
  2. Issuer Name and Ticker or Trading Symbol
CARDINAL HEALTH INC [CAH]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
CEO-Supply Chain Svcs.
(Last)
(First)
(Middle)
1430 WAUKEGAN ROAD
3. Date of Earliest Transaction (Month/Day/Year)
05/16/2006
(Street)

MCGAW PARK, IL 60085
4. If Amendment, Date Original Filed(Month/Day/Year)
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)
2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)
4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)
5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)
6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)
7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Shares 05/16/2006   M   37,500 A $ 31.167 73,582 D  
Common Shares 05/16/2006   S   37,300 D $ 68.3 36,282 D  
Common Shares 05/16/2006   S   200 D $ 68.43 36,082 D  
Common Shares               5,774 I By 401(k) plan
Common Shares               2,816 I By ESPP

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)
2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)
5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)
6. Date Exercisable and Expiration Date
(Month/Day/Year)
7. Title and Amount of Underlying Securities
(Instr. 3 and 4)
8. Price of Derivative Security
(Instr. 5)
9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)
10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)
11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Option (right to buy) (1) $ 31.167 05/16/2006   M     1 11/15/2002 11/15/2009 Common Shares 37,500 (2) 0 D  
Option (right to buy) (1) $ 47.33             03/01/2002 03/01/2009 Common Shares 18,600   1 D  
Option (right to buy) (1) $ 66.083             11/20/2003 11/20/2010 Common Shares 31,500   1 D  
Option (right to buy) (1) $ 68.1             11/19/2004 11/19/2011 Common Shares 44,604   1 D  
Option (right to buy) (1) $ 67.9             11/18/2005 11/18/2012 Common Shares 53,019   1 D  
Option (right to buy) (1) $ 61.38             11/17/2006 11/17/2013 Common Shares 25,000   1 D  
Option (right to buy) (1) $ 61.38             11/17/2006 11/17/2013 Common Shares 60,280   1 D  
Option (right to buy) (1) $ 44.15             08/23/2007 08/23/2014 Common Shares 105,000   1 D  
Option (right to buy) (1) $ 58.88               (3) 09/02/2012 Common Shares 84,288   1 D  
Option (right to buy) (1) $ 62.38               (4) 09/15/2012 Common Shares 84,288   1 D  

Reporting Owners

Reporting Owner Name / Address Relationships
 Director  10% Owner  Officer  Other
LABRUM RONALD K
1430 WAUKEGAN ROAD
MCGAW PARK, IL 60085
      CEO-Supply Chain Svcs.  

Signatures

 Ronald K. Labrum   05/17/2006
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Stock option granted pursuant to the Cardinal Health, Inc. Equity Incentive Plan.
(2) Stock option was disposed of in connection with its exercise for no additional consideration beyond the option shares.
(3) Stock option vests in four equal annual installments beginning on 9/2/2006.
(4) Stock option vests in four equal annual installments beginning on 9/15/2006.

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