FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person *   SAFEGUARD SCIENTIFICS INC 2. Date of Event Requiring Statement (Month/Day/Year) 04/09/2010 3. Issuer Name and Ticker or Trading Symbol TENGION INC [TNGN] (Last) (First) (Middle) 435 DEVON PARK DRIVE, BLDG. 800 4. Relationship of Reporting Person(s) to Issuer (Check all applicable) __X__ Director _____ 10% Owner _____ Officer (give title below) _____ Other (specify below) 5. If Amendment, Date Original Filed(Month/Day/Year) (Street) WAYNE, PA 19087-1945 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Beneficially Owned

1.Title of Security (Instr. 4) 2. Amount of Securities Beneficially Owned (Instr. 4) 3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5) 4. Nature of Indirect Beneficial Ownership (Instr. 5)

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.			SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Series C Convertible Preferred Stock	  (1)	  (1)	Common Stock	284,198	$ (2)	I	By SDI (3)

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
SAFEGUARD SCIENTIFICS INC 435 DEVON PARK DRIVE, BLDG. 800 WAYNE, PA 19087-1945	  X	Â	Â	Â

Signatures

By: Brian J. Sisko SVP & General Counsel For: Safeguard Scientifics, Inc.		04/09/2010
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 5(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	These securities are Series C Convertible Preferred Stock of the Issuer and do not have an expiration date. These securities will convert automatically into shares of Common Stock upon the closing of the Issuer's initial public offering, subject to certain conditions.
(2)	Each share of Series C Convertible Preferred Stock will convert automatically into shares of Common Stock on a 14.5-to-1 basis immediately prior to the closing of the Issuer's initial public offering, subject to certain conditions.
(3)	The securities are indirectly owned by reporting person and are directly owned by Safeguard Delaware, Inc. ("SDI"), a wholly owned subsidiary of the reporting person. Reporting person may be deemed a director by virtue of its right to nominate a representative to serve on the issuer's board of directors. Gary Kurtzman currently serves as reporting person's representative on Issuer's board.

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