UNITED STATES
              SECURITIES AND EXCHANGE COMMISSION
                   Washington, D.C. 20549

                         SCHEDULE 14A

 Proxy Statement Pursuant to Section 14(a) of the Securities
            Exchange Act of 1934 (Amendment No.    ) 

Filed by the Registrant [ X ] 
Filed by a Party other than the Registrant [   ] 

Check the appropriate box: 

[ ]Preliminary Proxy Statement 
[ ]Confidential, for Use of the Commission Only (as permitted
   by Rule 14a-6(e)(2)) 
[X]Definitive Proxy Statement 
[ ]Definitive Additional Materials
[ ]Soliciting Material Pursuant to Section 240.14a-12 
            
                      SCIENTIFIC INDUSTRIES, INC. 
-----------------------------------------------------------------
       (Name of Registrant as Specified In Its Charter) 
                                                  
-----------------------------------------------------------------
(Name of Person(s) Filing Proxy Statement, if other than the
Registrant) 

Payment of Filing Fee (Check the appropriate box): 

[X] No fee required. 
[ ] Fee computed on table below per Exchange Act Rules
    14a-6(i)(4) and 0-11.  
    
    (1) Title of each class of securities to which transaction
        applies: 

-----------------------------------------------------------------
    (2) Aggregate number of securities to which transaction applies: 

----------------------------------------------------------------- 
    (3) Per unit price or other underlying value of transaction
        computed pursuant to Exchange Act Rule 0-11 (set forth the 
        amount on which the filing fee is calculated and state how 
        it was determined): 

----------------------------------------------------------------- 
    (4) Proposed maximum aggregate value of transaction: 

-----------------------------------------------------------------
    (5) Total fee paid: 

-----------------------------------------------------------------
[ ] Fee paid previously with preliminary materials. 

[ ] Check box if any part of the fee is offset as provided by
    Exchange Act Rule 0-11(a)(2) and identify the filing for which
    the offsetting fee was paid previously. Identify the previous
    filing by registration statement number, or the Form or Schedule
    and the date of its filing. 

    (1) Amount previously paid: 
                                 
-----------------------------------------------------------------
    (2) Form, Schedule or Registration Statement No.: 
                                
-----------------------------------------------------------------
    (3) Filing Party:                
                                 
-----------------------------------------------------------------
    (4) Date Filed: 
                                
----------------------------------------------------------------- 



                 SCIENTIFIC INDUSTRIES INC.
                       (LETTERHEAD)
                                                                       
                                                                       
                                                                       
                                                                       
                                            October 27, 2005
                                                                       
    
    Dear Fellow Stockholders:
    
           You are cordially invited to attend the 2005 Annual
    Meeting of Stockholders of Scientific Industries, Inc. which
    will be held at 10:30 a.m. (New York time) on Friday,
    December 2, 2005 at the Princeton Club, 15 West 43rd Street,
    New York, New York 10036.
    
           Information concerning the matters to be considered
    and voted upon at the Annual Meeting is set out in the
    attached Notice of 2005 Annual Meeting of Stockholders and
    Proxy Statement. 
    
           It is important that your shares be represented at
    the 2005 Annual Meeting, regardless of the number of shares
    you hold and whether or not you plan to attend the meeting
    in person. Accordingly, please complete, sign and date the
    enclosed proxy card and return it as soon as possible in the
    accompanying business reply envelope so that your shares
    will be represented at the Annual Meeting. This will not
    limit your right to vote in person or to attend the meeting.
    
           Thank you for your continued support.
    
    
                                 Sincerely,
                                  
                      
                                 /s/Joseph I. Kesselman
                                 _______________________  
    
                                 Joseph I. Kesselman
                                 Chairman
                                 
   
                                           
           
    
                           SCIENTIFIC INDUSTRIES, INC.
                             70 ORVILLE DRIVE
                            BOHEMIA, NEW YORK 11716
                                     
                              _____________
                                     
              NOTICE OF 2005 ANNUAL MEETING OF STOCKHOLDERS
                                     
                             DECEMBER 2, 2005
    
    
    
            Notice is hereby given that the 2005 Annual Meeting
    of Stockholders (the "Annual Meeting") of Scientific
    Industries, Inc., a Delaware corporation (the "Company"),
    will be held on Friday, December 2, 2005, at 10:30 a.m. (New
    York time) at the Princeton Club, 15 West 43rd Street, New
    York, New York 10036, for the following purposes:
    
    
           1.     To elect two Class C Directors to the
                  Company's Board of Directors to serve until
                  the Company's annual meeting of stockholders
                  with respect to the year ending June 30, 2008
                  and until the election and qualification of
                  their respective successors.
           
           2.     To ratify the appointment of Nussbaum Yates &
                  Wolpow, P.C. as the Company's independent
                  auditors for the fiscal year ending June 30, 
                  2006.
    
           3.     To transact such other business as may
                  properly come before the Annual Meeting and
                  any adjournments or postponements thereof.   
                                                 
           The foregoing items of business are more fully
    described in the accompanying proxy statement. 
           
           The Board of Directors has fixed the close of
    business on October 27, 2005, as the record date for
    determination of stockholders entitled to notice of and to
    vote at, the Annual Meeting and at any adjournments or
    postponements thereof. 
    
           A complete list of the stockholders entitled to vote
    at the Annual Meeting will be available for inspection by
    any stockholder of the Company at the Annual Meeting.  In
    addition, the list will be open for examination by any
    stockholder of the Company for any purpose germane to the
    Annual Meeting during  ordinary business hours for a period
    of ten days prior to the Annual Meeting at the offices of
    the Company.
    
    
           
    
    YOU ARE REQUESTED TO FILL IN AND SIGN THE ENCLOSED FORM OF
    PROXY, WHICH IS BEING SOLICITED BY THE BOARD OF DIRECTORS OF
    THE COMPANY, AND MAIL IT PROMPTLY IN THE ENCLOSED POSTAGE
    PAID ENVELOPE.  ANY PROXY MAY BE REVOKED BY DELIVERY OF A
    LATER DATED PROXY. 
    
                                     
    
                                                
                                          By Order of your
                                          Board of Directors,
           
                           
                                          /s/Robert P. Nichols
                                          ____________________
                                  
                                          Robert P. Nichols
                                          Secretary

    
    Bohemia, New York
    October 27, 2005
           
   
    
    
    
    WHETHER OR NOT YOU PLAN TO ATTEND THE ANNUAL MEETING, WE
    KINDLY REQUEST THAT YOU PLEASE COMPLETE, SIGN, DATE, AND
    PROMPTLY RETURN THE ENCLOSED PROXY CARD IN THE POSTAGE PAID
    ENVELOPE PROVIDED.  IF YOU ARE A STOCKHOLDER OF RECORD AND
    YOU ATTEND THE ANNUAL MEETING, YOU MAY VOTE IN PERSON IF YOU
    WISH, EVEN IF YOU HAVE PREVIOUSLY RETURNED YOUR PROXY CARD.
    
    
                                 
                                 
                     YOUR VOTE IS IMPORTANT 
                                 
    

                                 
                                 
                   SCIENTIFIC INDUSTRIES, INC.
                         70 ORVILLE DRIVE
                     BOHEMIA, NEW YORK 11716
                                 
                         PROXY STATEMENT
                        _________________
                                 
               2005 ANNUAL MEETING OF STOCKHOLDERS
                  TO BE HELD ON DECEMBER 2, 2005
                        _________________
                                 
                     SOLICITATION OF PROXIES

            This proxy statement is furnished in
    connection with the solicitation of proxies by and on behalf
    of the Board of Directors (the "Board") of Scientific
    Industries, Inc., a Delaware corporation (the "Company"),
    for use at the 2005 Annual Meeting of Stockholders (the
    "Annual Meeting") to be held at the Princeton Club, 15 West
    43rd Street, New York, New York 10036, on Friday, December
    2, 2005, at 10:30 a.m. (New York time), and at any
    adjournments or postponements thereof.
    
           At the Annual Meeting, stockholders of the Company
    will be asked to:  (1) elect two Directors of the Company to
    serve until the Company's annual meeting of stockholders
    with respect to the fiscal year ending June 30, 2008, and
    until the election and qualification of their respective
    successors; (2) ratify the appointment of Nussbaum Yates &
    Wolpow, P. C., as the Company's independent auditors for the
    fiscal year ending June 30, 2006; and (3) transact such
    other business as may properly come before the Annual
    Meeting and any adjournments or postponements thereof.  
    
                    RECORD DATE, VOTING RIGHTS

           Only stockholders of record of the Company's
    Common Stock, par value $0.05 per share (the "Common
    Stock"), as of the close of business on October 27, 2005
    (the "Record Date"), are entitled to notice of and to vote
    at the Annual Meeting and any adjournments or postponements
    thereof.  On the Record Date, there were 989,686 shares of
    Common Stock issued and outstanding.  Each share of Common
    Stock is entitled to one vote.
           
           The presence at the Annual Meeting, in person or by a
    properly executed proxy, of the holders of a majority of the
    outstanding shares of  the Company's Common Stock as of the
    Record Date is necessary to constitute a quorum. 
    Abstentions and broker "non-votes" are included in the
    determination of the number of shares of Common Stock
    present at the Annual Meeting for quorum purposes.  A broker
    "non-vote" occurs when a nominee holding shares of Common
    Stock for a beneficial owner does not vote on a particular
    proposal because the nominee does not have discretionary
    voting power with respect to that item and has not received
    instructions from the beneficial owner. 
                                         
    
            
                                   
    
    
                           
           VOTING OF PROXIES, REVOCATION, SOLICITATION
                                 
            All stockholders who deliver properly executed and
    dated proxies to the Company prior to the Annual Meeting
    will be deemed present at the Annual Meeting regardless of
    whether such proxies direct the proxy holders to vote for or
    against, or to withhold or abstain from voting.  The
    proxies, when properly executed and returned to the Company,
    unless otherwise indicated, will be voted in accordance with
    the instructions given therein by the person executing the
    proxy.  In the absence of instructions, properly executed
    proxies will be voted FOR (1) the election of the Board's
    nominees, Joseph G. Cremonese and Roger B. Knowles, as 
    Directors of the Company; and (2) the ratification of the
    appointment by the Board of Directors of Nussbaum Yates &
    Wolpow, P.C., as the Company's independent auditors for the
    fiscal year ending June 30, 2006.

            Any stockholder who executes and delivers a
    proxy may revoke it at any time before it is voted by
    delivering a written notice of such revocation to the
    Secretary of the Company at the address of the Company set
    forth in this proxy statement, by submitting a properly
    executed proxy bearing a later date, or by appearing at the
    Annual Meeting and requesting the return of the proxy or by
    voting in person.  In accordance with applicable rules,
    boxes and a designated space are provided on the proxy card
    for stockholders to mark if they wish either to vote for or
    withhold authority to vote for the nominees for Directors,
    or to vote for or against or to abstain from voting for the
    proposal to ratify the appointment of the Company's
    independent auditors.
    
           A stockholder's attendance at the Annual Meeting will
    not, by itself, revoke a proxy given by that stockholder. 
    Stockholders vote at the Annual Meeting by casting ballots
    (in person or by proxy) which are tabulated by a person who
    is appointed by the Board of Directors before the Annual
    Meeting to serve as inspector of election at the Annual
    Meeting and who has executed and verified an oath of office.
         
           It is anticipated that this proxy statement, the
    enclosed proxy card and the Company's Annual Report will be
    mailed to the Company's stockholders on or about November 2, 
    2005.
                                 
                      PRINCIPAL STOCKHOLDERS
                                 
    The following table sets forth as of October 25, 2005
    certain information as to each person who to the Company's
    knowledge, based upon such person's representations or
    publicly available filings, beneficially owned more than 5%
    of the shares of the Company's Common Stock as of that date:
    
    Name and Address of    Shares Beneficially     Percent of
    Beneficial Owner       Owned**                 Class***
    __________________     ___________________     __________

       
    James S. Segasture*       187,250 (1)            18.8
    
    Lowell A. Kleiman         139,581 (2)            14.1
    16 Walnut Street
    Glen Head, NY 11545
    
    Joseph I. Kesselman*       63,520 (3)             6.2
    
    Roger B. Knowles*          50,595 (4)             5.0
    
    Arthur M. Borden*          59,540 (5)             5.9

    ______________
    *   Address is c/o Scientific Industries, Inc., 70 Orville
    Drive, Bohemia, New York 11716.
    
    

    
    **   Beneficial ownership, as such term is used herein, is
    determined in accordance with Rule 13d-3(d)(1) promulgated
    under the Securities Exchange Act of 1934, as amended, (the
    "Exchange Act") and includes voting and/or investment power
    with respect to shares of Common Stock of the Company. 
    Unless otherwise indicated, the named person possesses sole
    voting and investment power with respect to the shares.  The
    shares shown include shares issuable pursuant to options
    held by the named person that may be exercised within 60
    days of the date indicated above.
    
    ***   Percentages of ownership are based upon the number of
    shares of Common Stock issued and outstanding.  Shares of
    Common Stock that may be acquired pursuant to options that
    are exercisable within 60 days of the date indicated above
    are deemed outstanding for computing the percentage
    ownership of the person holding such options, but are not
    deemed outstanding for the percentage ownership of any other 
    person.
    
            
            (1)    Includes 4,000 shares issuable upon exercise
                   of options and 493 shares owned by his wife.
            
            (2)    Based on information reported in his Schedule
                   13(d)  filed with the Securities and Exchange
                   Commission on October 30, 2002. 
            
            (3)    Includes 23,000 shares issuable upon exercise
                   of options and 735 shares of Common Stock
                   owned jointly with his wife.
            
            (4)    Includes 26,258 shares owned by his wife,
                   1,337 shares owned by a trust of which he is
                   a trustee, beneficial ownership of which is
                   disclaimed by him, and 23,000 shares issuable
                   upon exercise of options.
            
            (5)    Includes 23,000 shares issuable upon exercise
                   of options.
            
            
            
   
            
                            PROPOSAL 1
                                 
                      ELECTION OF DIRECTORS
            
            
           GENERAL
            
            The Company's Certificate of Incorporation provides
    for a classified Board of Directors, consisting of three
    classes, each class serving a three-year term on a staggered
    basis.  The Board of Directors is currently comprised of
    five members, of whom two are Class A Directors, one is a
    Class B Director and two are Class C Directors.  At the
    Annual Meeting, two Class C Directors are to be elected to
    serve until the annual meeting of stockholders with respect
    to the fiscal year ending June 30, 2008, and until their
    successors are duly elected and qualified.  Shares of Common
    Stock represented by proxies solicited by the Board of
    Directors will be voted for the nominees hereinafter named
    if authority to do so is not specifically withheld.  If for
    any reason said nominees shall become unavailable for
    election, which is not now anticipated, the proxies will be
    voted for a substitute nominee designated by the Board of 
    Directors.
    
            The Directors of the Company are elected by the
    affirmative vote of the holders of a plurality of the shares
    of Common Stock present in person or represented by proxy at
    the Annual Meeting and entitled to vote.  A plurality means
    that the nominee with the largest number of votes is elected
    as Director. In tabulating the vote, abstentions and broker
    "non-votes" will be disregarded and will have no effect on
    the outcome of the vote. 
           
           THE BOARD OF DIRECTORS RECOMMENDS THAT STOCKHOLDERS
    VOTE FOR THE ELECTION OF THE NOMINEES IDENTIFIED BELOW TO
    THE BOARD OF DIRECTORS.
    
    
    
           NOMINEES
    
            The Board of Directors has designated Messrs. Joseph
    G. Cremonese and Roger B. Knowles, both currently Class C
    Directors, as their nominees for election.
    
            Joseph G. Cremonese (age 69), a Director since
    November 2002, has been a marketing consultant to the
    Company since 1996.  He has been since 1991, President of
    Laboratory Innovation Company, Ltd., which is a vehicle for
    technology transfer and consulting services for companies
    engaged in the production and sale of products for science
    and biotechnology.  Since March 2003, Mr. Cremonese has been
    a director of and consultant to Proteomics, Inc., a producer
    of recombinant proteins for medical research.  Prior to
    1991, he had been employed by Fisher Scientific, a
    distributor and presently the Company's largest customer.
            
            Roger B. Knowles (age 80), a Director since 1965, is
    retired.  During the past five years he has been involved in
    liquidating various real estate and manufacturing concerns. 
         
    
           OTHER DIRECTORS
           
            Messrs. Arthur M. Borden and James S. Segasture are
    Class A Directors whose current terms expire at the annual
    meeting with respect to the fiscal year ending June 30,
    2006.   Mr. Joseph Kesselman is a Class B Director whose
    current term expires at the annual meeting with respect to
    the fiscal year ending June 30, 2007.
    


            Arthur M. Borden, Esq. (age 85), a Director since
    1974, has been counsel to the law firm of Katen Muchin Zavis
    Rosenman (formerly Rosenman & Colin) during the past five
    years.  He is a director of Supreme Industries, Inc., a
    nationwide manufacturer of specialized truck bodies.
    
            James S. Segasture (age 69), a Director since 1991,
    has been a private investor since February 1990.
    
            Joseph I. Kesselman (age 80), a Director since 1961
    and Chairman of the Board since August 29, 2002, has been
    for more than five years a consultant to various
    corporations.  He is a director of Nuclear and Environmental
    Protection Inc., Hopare Holding, S.A. (a Swiss company), and
    Infranor Inc., a developer and manufacturer of servo
    systems. 
           
    
           STOCK OWNERSHIP
    
            The following table sets forth, as of October 27,
    2005, the number of shares of Common Stock beneficially
    owned by (i) each Director of the Company, including the
    nominees for Directors, (ii) each executive officer of the
    Company identified in the Summary Compensation Table under
    "Executive Officers," and (iii) all directors and executive
    officers as a group.
    
     Beneficial Owner           Number             Percentage
     ________________           __________         __________

     Arthur M. Borden           59,540(1)          5.9%

     Joseph G. Cremonese        21,210(2)          2.1%
  
     Joseph I. Kesselman        63,520(3)          6.2%

     Roger B. Knowles           50,595(4)          5.0%

     Robert P. Nichols          27,800(5)          2.7%

     James S. Segasture        187,250(6)         18.8%

     Helena R. Santos           21,000(7)          2.1%

     All current directors and
      executive officers as a 
      group (7 persons)        430,915(8)         38.9%

    
            
            (1)    Includes 23,000 shares issuable upon exercise
                   of options.
            (2)    Includes 15,000 shares owned jointly with his
                   wife and 5,000 shares issuable upon exercise
                   of options.
            (3)    Includes 23,000 shares issuable upon exercise
                   of options and 735 shares of Common Stock
                   owned jointly with his wife.
            (4)    Includes 26,258 shares owned by his wife,
                   1,337 shares owned by a trust of which he is
                   a trustee, beneficial ownership of which is
                   disclaimed by him, and 23,000 shares issuable
                   upon exercise of options.
            (5)    Includes 25,000 shares issuable upon exercise
                   of options.
            (6)    Includes 4,000 shares issuable upon exercise
                   of options and 493 shares owned by his wife.
            (7)    Includes 15,000 shares issuable upon exercise
                   of options.
            (8)    Includes 118,000 shares issuable upon
                   exercise of options.


            
            
                  BOARD COMMITTEES
            
                   Joseph I. Kesselman and James S. Segasture
            have been appointed as the sole members of the Company's 
            Stock Option Committee to serve at the discretion of the 
            Board and to administer the Company's 2002 Stock Option Plan
            ("2002 Plan"). 
            
                   The Board of Directors acts as the Company's
            Audit Committee.
            
            
                  MEETINGS
            
                   During the fiscal year ended June 30, 2005,
            the Board of Directors held five meetings, at each of 
            which all Directors were present except for one director 
            who did not attend one meeting.
            
            
                  DIRECTORS' COMPENSATION AND OPTIONS
            
                   The Company currently pays each non-employee
            Director a quarterly retainer of $750 and a fee of $500 
            for each meeting attended, plus reimbursement for out-of-pocket 
            expenses incurred in connection with attendance at board
            meetings in the amount of $50 or the Director's itemized 
            expenses, whichever is greater.  Mr. Joseph I. Kesselman, as 
            Chairman of the Board, also receives a monthly fee of $750.  
            During fiscal 2005, the fees to non-employee Directors 
            aggregated $36,000.
            
                   Pursuant to the Company's 1992 Stock Option Plan
            ("1992 Plan") options to purchase 3,000 shares of Common 
            Stock at the then fair market value were granted to each 
            director who was on the Board of Directors on the first 
            business day of each March in 1993, 1994, 1995, and 1996, 
            namely Messrs. Borden, Kesselman, Knowles and Segasture.  
            In addition, in December 1997 and through December 2001 
            the Board of Directors granted under the 2002 Plan annually 
            options to purchase 4,000 shares of Common Stock for each of 
            them exercisable at the fair market value on the date of grant. 
            Accordingly, as of June 30, 2005,  the Company had granted 
            under the 1992 Plan to the foregoing four non-employee Directors 
            options to purchase an aggregate of 128,000 shares of Common
            Stock, or options to purchase 32,000 shares of Common Stock 
            for each.  The fair market value per share of Common Stock on the 
            dates of grant ranged from $0.50 for options granted in 1993 to 
            $2.40 in 2001.  As of June 30, 2005, options under the 1992 Plan 
            with respect to 49,000 shares had been exercised by the 
            Directors.  In addition, they had exercised options with respect 
            to 48,000 shares granted to them prior to the adoption of 
            the 1992 Plan.
            
                   Under the Company's 2002 Plan, none of the Directors at 
            the time of its adoption by the Board of Directors (subsequently 
            approved by stockholders) were eligible to receive option grants.  
            Mr. Joseph G. Cremonese who was elected Director at the 2002 
            Annual Meeting of Stockholders, was granted on December 1, 2003 
            an option to purchase 5,000 shares of Common Stock at the fair
            market value of $1.35 per share. 
            
            
       
            
            
            
            
            
                          
            EXECUTIVE OFFICERS
                    
                   The following are the Executive Officers of the Company:
                   
                   Helena R. Santos, CPA (age 41), employed by the Company 
            since 1994, was appointed in August 2002 as President, Chief 
            Executive Officer and Treasurer.  Previously she served as 
            Vice President, Controller from 1997 and Secretary from May 2001.  
            Ms. Santos was an internal auditor with a major defense contractor
            from March 1991 to April 1994.  She had been previously employed in 
            public accounting.
                    
                   Robert P. Nichols (age 44), employed by the Company since 
            February 1998, was appointed in August 2002 as Executive Vice
            President.  He had been Vice President, Engineering from May 2001.
            Prior to joining the Company, he was an Engineer Manager with 
            Bay Side Motion Group, a precision motion equipment manufacturer 
            from January 1996 to February 1998.        
            
                   The executive officers of the Company are elected by the 
            Board of Directors and hold office until their respective 
            successors are elected and qualified or until his or her earlier 
            resignation or removal.  None of the officers need to be Directors, 
            and more than one office may be held by the same person.  There 
            is no arrangement or understanding between any executive officer 
            and any other person regarding election as an officer.  There are 
            no family relationships between any Director and any executive
            officer of the Company.
                   
                   The Company has employment agreements with Ms. Helena R. 
            Santos and Mr. Robert P. Nichols effective through December 31, 2006
            providing for Ms. Santos a base annual salary of $110,000, and for 
            Mr. Nichols a base annual salary of $105,000.  Each agreement 
            authorizes annual bonuses by the Board based upon performance
            criteria and contains noncompetition and confidentiality covenants.
            
                   The following table summarizes all compensation paid by 
            the Company to its then Chief Executive Officer and President and 
            Executive Vice President with respect to each of the three fiscal 
            years ended June 30, 2005, 2004 and 2003.  No other executive 
            officer earned in excess of $100,000 in any of such fiscal periods.
                    SUMMARY COMPENSATION TABLE
                             
                       ANNUAL COMPENSATION
            
                                                        All Other         
                          Fiscal                        Compen-
     Name                 Year    Salary    Bonus       sation       
     ___________________  ______  ______    _____       __________ 
                                                              

     Helena R. Santos (1) 2005   $108,200  $   -        $   -
                          2004   $100,000  $   -        $   -
                          2003   $ 98,500  $   -        $   -
     Robert P. Nichols (2)2005   $103,200  $   -        $   -
                          2004   $ 95,000  $   -        $   -
                          2003   $ 94,000  $   -        $   -
     Lowell A. Kleiman (1)2003   $ 53,300  $   -        $ 19,500
                                             
     (1) Ms. Santos was appointed Chief Executive Officer and President
     on August 29, 2002 following the termination of Mr. Kleiman's
     employment.  His other compensation represents benefits accrued
     upon termination.

     (2) Mr. Nichols was appointed Executive Vice President on August
     29, 2002. 
                                                    
                                                      
                 
            
            RELATED TRANSACTIONS
            
                   Mr. Joseph G. Cremonese, who was elected a
      Class C Director at the Annual Meeting of Stockholders in 
      November 2002 or his affiliate, Laboratory Innovation Company, 
      Ltd., have been providing independent marketing consulting
      services to the Company for approximately nine years.  The 
      services have been rendered since January 1, 2003 pursuant to 
      a consulting agreement which was amended in March 2005.  The
      agreement as amended provides that Mr. Cremonese and his 
      affiliate render, at the request of the Company, through 
      December 31, 2006 marketing consulting services of at least 72
      (originally 80), but not more than 96, days per year at the 
      rate of $500 (originally $450) per day with a monthly cap of 
      $3,000, with the Company's obligation reduced to the extent 
      the consulting services are less than 72 days for the 12 month 
      period.  The agreement contains confidentiality and non-competition 
      covenants.  During fiscal 2005 and fiscal 2004, the Company paid an 
      aggregate of $31,000 and $33,200 respectively for the consulting 
      services.                            
                   
            SECTION 16(A) REPORTING
                          
                   The Company believes that, for the year ended
      June 30, 2005, its officers, directors and 10% stockholders timely 
      complied with all filing requirements of Section 16(a) of the 
      Securities Exchange Act of 1934, as amended.                   
                                             
            
            
                            PROPOSAL 2
                                 
       APPOINTMENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
                                         
                   The Board of Directors, subject to stockholders'
       approval, appointed Nussbaum Yates & Wolpow, P.C. ("NY&W") as 
       independent auditors of the Company for its financial statements 
       for fiscal year ending June 30, 2006.  NY&W has audited the 
       consolidated financial statements of the Company since 1991.  A 
       representative of that firm is expected to be present at the Annual 
       Meeting, and will have an opportunity to make a statement to the 
       stockholders and will be available to respond to appropriate questions.  
       The ratification of the appointment will require the affirmative 
       vote of the holders of a majority of the outstanding shares of Common 
       Stock present in person or represented by proxy at the Annual Meeting 
       and entitled to vote.  Abstentions will be included in determining the 
       number of shares of Common Stock present or represented and entitled 
       to vote for purposes of approval and will have the effect of votes 
       "against" the proposal.  Broker  "non-votes"  will not be counted in 
       determining the number of shares of Common Stock present or represented 
       and entitled to vote to approve the proposal and will therefore not 
       have the effect of votes either "for" or "against".
                          
                  Stockholder ratification of the appointment is not
       required by the Company's Certificate of Incorporation or By-laws or 
       otherwise.  If the stockholders fail to ratify the appointment, the
       Board of Directors will reconsider whether to retain that firm.  
       Even if the appointment is ratified, the Board of Directors in its 
       discretion may direct the appointment of a different independent 
       registered public accounting firm at any time during the year
       if the Board of Directors determines that such a change would be in 
       the best interests of the Company and its stockholders.  
            
                 The following is a description of the fees incurred
       by the Company for services by NY&W during the fiscal years ended 
       June 30, 2005 and 2004:
            
       Audit Fees: The Company incurred fees of approximately $25,200 and 
       $24,550 to NY&W in connection with its audit of the Company's 
       financial statements and review of the Company's interim financial 
       statements included in the Company's Quarterly Reports on Form 10-
       QSB during the fiscal year ended June 30, 2005 and 2004, respectively.
                                                        
       Tax Fees: The Company incurred fees of approximately $4,000 to NY&W 
       for each of the fiscal years ended June 30, 2005 and 2004 in 
       connection with preparation of the corporate tax returns.
            
       Financial Information Systems Design and Implementation Fees: The 
       Company did not engage NY&W during each of the two years to provide
       advice to the Company regarding financial information systems design 
       and implementation.  
            
       Other Fees:  The Company paid $3,600 to NY&W in connection with its 
       review of amendments of the Company's annual and quarterly reports 
       filed under the Securities Exchange Act of 1934 in fiscal 2005.  
       NY&W did not perform other non-audit services in the prior fiscal year.
            
       THE BOARD OF DIRECTORS UNANIMOUSLY RECOMMENDS THAT THE STOCKHOLDERS 
       VOTE FOR THE RATIFICATION OF THE APPOINTMENT OF NUSSBAUM YATES &
       WOLPOW, P.C. AS THE COMPANY'S INDEPENDENT REGISTERED PUBLIC ACCOUNTING 
       FIRM FOR THE FISCAL YEAR ENDING JUNE 30, 2006.
            
                          OTHER MATTERS
            
                  The Board of Directors is not aware of any matters other 
       than those set forth in this proxy statement that will be presented 
       for action at the Annual Meeting; however, if any other matters 
       properly come before the Annual Meeting, the persons named as proxies 
       intend to vote the shares of Common Stock they represent in accordance 
       with their judgment on such matters.
            
            
                      ADDITIONAL INFORMATION
            
                  THE COMPANY'S ANNUAL REPORT TO STOCKHOLDERS FOR THE FISCAL 
       YEAR ENDED JUNE 30, 2005, INCLUDES ITS ANNUAL REPORT ON FORM 10-KSB FOR
       THE YEAR WHICH WAS FILED WITH THE U.S. SECURITIES AND EXCHANGE COMMISSION
       ON SEPTEMBER 28, 2005.  THE ANNUAL REPORT TO STOCKHOLDERS ON FORM 10-KSB 
       IS NOT PART OF THIS PROXY MATERIAL, BUT IS BEING MAILED TO STOCKHOLDERS 
       WITH THIS PROXY SOLICITATION. 
            
                      STOCKHOLDER PROPOSALS
            
                  Proposals of stockholders of the Company intended to be 
       presented at the Company's 2005 Annual Meeting of Stockholders following 
       the year ended June 30, 2006 must be received by the Secretary of the 
       Company for inclusion in the appropriate proxy materials no later 
       than July 2, 2006. 
            
                    EXPENSES AND SOLICITATION
            
             The entire cost of soliciting proxies will be borne by the 
       Company. In addition to the use of the mails, proxies may be solicited 
       by officers, directors and regular employees of the Company 
       personally or by telephone.  No additional compensation will be paid 
       to such persons for any additional solicitations.  The Company will also
       request securities brokers, custodians, nominees and fiduciaries who 
       hold shares of Common Stock of record to forward solicitation material 
       to the beneficial owners of such shares, and will reimburse them for 
       their reasonable out-of-pocket expenses in forwarding such 
       soliciting materials.
            
                                                        
            
                                                              
                                                               
                            By Order of Your Board of Directors,
            
                            /s/Robert P. Nichols
                            ____________________            
                            Robert P. Nichols,
                            Secretary



_______________________________________________________________________
            
Bohemia, New York
October 27, 2005  

             SCIENTIFIC INDUSTRIES, INC.
        PROXY FOR ANNUAL MEETING OF STOCKHOLDERS
                   December 2, 2005

     THIS PROXY IS SOLICITED BY THE BOARD OF DIRECTORS


The undersigned hereby appoints Joseph I. Kesselman and Arthur M. 
Borden, and each of them, with full power of substitution, to vote, 
as a holder of the common stock, par value $0.05 per share 
("Common Stock"), of Scientific Industries, Inc., a Delaware corporation 
(the "Company"), all the shares of Common Stock which the undersigned 
is entitled to vote, through the execution of a proxy with respect to the 
2005 Annual Meeting of Stockholders of the Company (the "Annual Meeting"), 
to be held at the Princeton Club, 15 West 43rd Street, New York, 
New York, on Friday, December 2, 2005 at 10:30 a.m. New York time, and 
any and all adjournments or postponements thereof, and authorizes and 
instructs said proxies to vote in the manner directed below.

The Board of Directors recommends the vote FOR the election of the 
nominees for Class C Directors named below and proposal 2.

1.	Election of Class C Directors:	

JOSEPH G. CREMONESE	ROGER B. KNOWLES

FOR both nominees  (  )   WITHHOLD for both nominees  (  )


If you do not wish your shares voted FOR one of the two nominees, draw 
a line through that person's name above.


2.	Proposal to ratify the appointment of Nussbaum, Yates & 
Wolpow, P.C., as independent auditors of the Company for the fiscal 
year ending June 30, 2006.

FOR   (  )		AGAINST   (  )		ABSTAIN   (  )

3.	In their discretion, the proxies are authorized to vote upon 
such other business as may properly come before such meeting or 
adjournment or postponement thereof.

THIS PROXY IS CONTINUED ON THE REVERSE SIDE, PLEASE VOTE,
SIGN AND DATE ON REVERSE SIDE AND RETURN PROMPTLY.

_____________________________________________________________________


BACK OF CARD



PROPERLY EXECUTED AND RETURNED PROXY CARDS WILL BE VOTED IN THE 
MANNER DIRECTED HEREIN BY THE UNDERSIGNED STOCKHOLDER.  IF NO 
INSTRUCTIONS TO THE CONTRARY ARE MADE, THIS PROXY WILL BE VOTED FOR 
THE ELECTION OF EACH OF THE NAMED NOMINEES AS DIRECTORS AND APPROVAL 
OF PROPOSAL NO. 2 LISTED ON THE REVERSE SIDE OF THIS CARD.

You may revoke this proxy at any time before it is voted by (i) filing 
a revocation with the Secretary of the Company, (ii) submitting a duly 
executed proxy bearing a later date or time than the date or time of 
the proxy being revoked; or (iii) attending the Annual Meeting and 
voting in person. A stockholder's attendance at the Annual 
Meeting will not by itself revoke a proxy given by the stockholder.

                          (Please sign exactly as the name appears 
                          hereon.  Joint owners should each sign.  When 
                          signing as attorney, executor, administrator, 
                          trustee or guardian, please give full title as 
                          such.  If a corporation, please sign with full 
                          corporate name by the president or other 
                          authorized officer.  If a partnership, please 
                          sign in the partnership name by authorized 
                          person.)




Dated:___________,2005				_______________________________
							Signature

PLEASE COMPLETE, SIGN, DATE               __________________________________
AND RETURN THE PROXY CARD                 Signature, if held by joint owners
PROMPTLY USING THE 
ENCLOSED ENVELOPE.